292 related articles for article (PubMed ID: 18582474)
1. Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites.
Xu C; Wu L; Cui G; Botuyan MV; Chen J; Mer G
J Mol Biol; 2008 Aug; 381(2):361-72. PubMed ID: 18582474
[TBL] [Abstract][Full Text] [Related]
2. A divalent FHA/BRCT-binding mechanism couples the MRE11-RAD50-NBS1 complex to damaged chromatin.
Hari FJ; Spycher C; Jungmichel S; Pavic L; Stucki M
EMBO Rep; 2010 May; 11(5):387-92. PubMed ID: 20224574
[TBL] [Abstract][Full Text] [Related]
3. MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks.
Wu L; Luo K; Lou Z; Chen J
Proc Natl Acad Sci U S A; 2008 Aug; 105(32):11200-5. PubMed ID: 18678890
[TBL] [Abstract][Full Text] [Related]
4. Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage.
Chapman JR; Jackson SP
EMBO Rep; 2008 Aug; 9(8):795-801. PubMed ID: 18583988
[TBL] [Abstract][Full Text] [Related]
5. Mdc1 modulates the interaction between TopBP1 and the MRN complex during DNA damage checkpoint responses.
Choi SH; Yoo HY
Biochem Biophys Res Commun; 2016 Oct; 479(1):5-11. PubMed ID: 27590578
[TBL] [Abstract][Full Text] [Related]
6. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin.
Melander F; Bekker-Jensen S; Falck J; Bartek J; Mailand N; Lukas J
J Cell Biol; 2008 Apr; 181(2):213-26. PubMed ID: 18411307
[TBL] [Abstract][Full Text] [Related]
7. Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Williams RS; Dodson GE; Limbo O; Yamada Y; Williams JS; Guenther G; Classen S; Glover JN; Iwasaki H; Russell P; Tainer JA
Cell; 2009 Oct; 139(1):87-99. PubMed ID: 19804755
[TBL] [Abstract][Full Text] [Related]
8. Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.
Rodriguez M; Yu X; Chen J; Songyang Z
J Biol Chem; 2003 Dec; 278(52):52914-8. PubMed ID: 14578343
[TBL] [Abstract][Full Text] [Related]
9. A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage.
Lloyd J; Chapman JR; Clapperton JA; Haire LF; Hartsuiker E; Li J; Carr AM; Jackson SP; Smerdon SJ
Cell; 2009 Oct; 139(1):100-11. PubMed ID: 19804756
[TBL] [Abstract][Full Text] [Related]
10. Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation.
Mendez G; Cilli D; Berardinelli F; Viganotti M; Ascenzi P; Tanzarella C; Antoccia A; di Masi A
IUBMB Life; 2012 Oct; 64(10):853-61. PubMed ID: 22941933
[TBL] [Abstract][Full Text] [Related]
11. Comparison of the structures and peptide binding specificities of the BRCT domains of MDC1 and BRCA1.
Campbell SJ; Edwards RA; Glover JN
Structure; 2010 Feb; 18(2):167-76. PubMed ID: 20159462
[TBL] [Abstract][Full Text] [Related]
12. MDC1 is required for the intra-S-phase DNA damage checkpoint.
Goldberg M; Stucki M; Falck J; D'Amours D; Rahman D; Pappin D; Bartek J; Jackson SP
Nature; 2003 Feb; 421(6926):952-6. PubMed ID: 12607003
[TBL] [Abstract][Full Text] [Related]
13. Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin.
Spycher C; Miller ES; Townsend K; Pavic L; Morrice NA; Janscak P; Stewart GS; Stucki M
J Cell Biol; 2008 Apr; 181(2):227-40. PubMed ID: 18411308
[TBL] [Abstract][Full Text] [Related]
14. MDC1 is a mediator of the mammalian DNA damage checkpoint.
Stewart GS; Wang B; Bignell CR; Taylor AM; Elledge SJ
Nature; 2003 Feb; 421(6926):961-6. PubMed ID: 12607005
[TBL] [Abstract][Full Text] [Related]
15. Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail.
Lee MS; Edwards RA; Thede GL; Glover JN
J Biol Chem; 2005 Sep; 280(37):32053-6. PubMed ID: 16049003
[TBL] [Abstract][Full Text] [Related]
16. MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner.
Strauss C; Halevy T; Macarov M; Argaman L; Goldberg M
DNA Repair (Amst); 2011 Aug; 10(8):806-14. PubMed ID: 21622030
[TBL] [Abstract][Full Text] [Related]
17. Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage.
Lee JH; Xu B; Lee CH; Ahn JY; Song MS; Lee H; Canman CE; Lee JS; Kastan MB; Lim DS
Mol Cancer Res; 2003 Jul; 1(9):674-81. PubMed ID: 12861053
[TBL] [Abstract][Full Text] [Related]
18. Interactions between BRCT repeats and phosphoproteins: tangled up in two.
Glover JN; Williams RS; Lee MS
Trends Biochem Sci; 2004 Nov; 29(11):579-85. PubMed ID: 15501676
[TBL] [Abstract][Full Text] [Related]
19. Functional analysis of FHA and BRCT domains of NBS1 in chromatin association and DNA damage responses.
Zhao S; Renthal W; Lee EY
Nucleic Acids Res; 2002 Nov; 30(22):4815-22. PubMed ID: 12433983
[TBL] [Abstract][Full Text] [Related]
20. Dimerization Mediated by a Divergent Forkhead-associated Domain Is Essential for the DNA Damage and Spindle Functions of Fission Yeast Mdb1.
Luo S; Xin X; Du LL; Ye K; Wei Y
J Biol Chem; 2015 Aug; 290(34):21054-21066. PubMed ID: 26160178
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]