BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

381 related articles for article (PubMed ID: 18583988)

  • 21. Specific association of mouse MDC1/NFBD1 with NBS1 at sites of DNA-damage.
    Lee AC; Fernandez-Capetillo O; Pisupati V; Jackson SP; Nussenzweig A
    Cell Cycle; 2005 Jan; 4(1):177-82. PubMed ID: 15611643
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
    Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
    J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.
    So S; Davis AJ; Chen DJ
    J Cell Biol; 2009 Dec; 187(7):977-90. PubMed ID: 20026654
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The Mre11/Rad50/Nbs1 complex interacts with the mismatch repair system and contributes to temozolomide-induced G2 arrest and cytotoxicity.
    Mirzoeva OK; Kawaguchi T; Pieper RO
    Mol Cancer Ther; 2006 Nov; 5(11):2757-66. PubMed ID: 17121922
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins.
    Cervelli T; Palacios JA; Zentilin L; Mano M; Schwartz RA; Weitzman MD; Giacca M
    J Cell Sci; 2008 Feb; 121(Pt 3):349-57. PubMed ID: 18216333
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
    Jungmichel S; Clapperton JA; Lloyd J; Hari FJ; Spycher C; Pavic L; Li J; Haire LF; Bonalli M; Larsen DH; Lukas C; Lukas J; MacMillan D; Nielsen ML; Stucki M; Smerdon SJ
    Nucleic Acids Res; 2012 May; 40(9):3913-28. PubMed ID: 22234878
    [TBL] [Abstract][Full Text] [Related]  

  • 27. NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation.
    Anand R; Jasrotia A; Bundschuh D; Howard SM; Ranjha L; Stucki M; Cejka P
    EMBO J; 2019 Apr; 38(7):. PubMed ID: 30787182
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Functional analysis of FHA and BRCT domains of NBS1 in chromatin association and DNA damage responses.
    Zhao S; Renthal W; Lee EY
    Nucleic Acids Res; 2002 Nov; 30(22):4815-22. PubMed ID: 12433983
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel.
    Garner KM; Eastman A
    BMC Cancer; 2011 May; 11():206:1-13. PubMed ID: 21619594
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
    Agyeman A; Mazumdar T; Houghton JA
    Oncotarget; 2012 Aug; 3(8):854-68. PubMed ID: 23097684
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair.
    Robert F; Hardy S; Nagy Z; Baldeyron C; Murr R; Déry U; Masson JY; Papadopoulo D; Herceg Z; Tora L
    Mol Cell Biol; 2006 Jan; 26(2):402-12. PubMed ID: 16382133
    [TBL] [Abstract][Full Text] [Related]  

  • 32. MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends.
    Sharma S; Anand R; Zhang X; Francia S; Michelini F; Galbiati A; Williams H; Ronato DA; Masson JY; Rothenberg E; Cejka P; d'Adda di Fagagna F
    Cell Rep; 2021 Jan; 34(1):108565. PubMed ID: 33406426
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
    He J; Shi LZ; Truong LN; Lu CS; Razavian N; Li Y; Negrete A; Shiloach J; Berns MW; Wu X
    J Biol Chem; 2012 Sep; 287(38):31747-56. PubMed ID: 22833675
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair.
    Korsholm LM; Gál Z; Lin L; Quevedo O; Ahmad DA; Dulina E; Luo Y; Bartek J; Larsen DH
    Nucleic Acids Res; 2019 Sep; 47(15):8019-8035. PubMed ID: 31184714
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Deletion of NAD(P)H:quinone oxidoreductase 1 represses Mre11-Rad50-Nbs1 complex protein expression in cisplatin-induced nephrotoxicity.
    Kim YJ; Kim TW; Park SR; Kim HT; Jung DY; Ryu SY; Jung JY
    Toxicol Lett; 2016 Jan; 243():22-30. PubMed ID: 26723870
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 53BP1 promotes ATM activity through direct interactions with the MRN complex.
    Lee JH; Goodarzi AA; Jeggo PA; Paull TT
    EMBO J; 2010 Feb; 29(3):574-85. PubMed ID: 20010693
    [TBL] [Abstract][Full Text] [Related]  

  • 37. ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks.
    Lee KY; Im JS; Shibata E; Dutta A
    Mol Cell; 2017 Oct; 68(1):61-75.e5. PubMed ID: 28943310
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin.
    Folk WP; Kumari A; Iwasaki T; Pyndiah S; Johnson JC; Cassimere EK; Abdulovic-Cui AL; Sakamuro D
    J Biol Chem; 2019 Apr; 294(14):5700-5719. PubMed ID: 30733337
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Chromatin-associated MRN complex protects highly transcribing genes from genomic instability.
    Salifou K; Burnard C; Basavarajaiah P; Grasso G; Helsmoortel M; Mac V; Depierre D; Franckhauser C; Beyne E; Contreras X; Dejardin J; Rouquier S; Cuvier O; Kiernan R
    Sci Adv; 2021 May; 7(21):. PubMed ID: 34020942
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex.
    Chailleux C; Tyteca S; Papin C; Boudsocq F; Puget N; Courilleau C; Grigoriev M; Canitrot Y; Trouche D
    Biochem J; 2010 Feb; 426(3):365-71. PubMed ID: 20070254
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 20.