387 related articles for article (PubMed ID: 18585981)
1. Cholesterol homeostasis by the intestine: lessons from Niemann-Pick C1 Like 1 [NPC1L1).
Davis HR; Basso F; Hoos LM; Tetzloff G; Lally SM; Altmann SW
Atheroscler Suppl; 2008 Sep; 9(2):77-81. PubMed ID: 18585981
[TBL] [Abstract][Full Text] [Related]
2. Niemann-Pick C1 Like 1 (NPC1L1) an intestinal sterol transporter.
Davis HR; Altmann SW
Biochim Biophys Acta; 2009 Jul; 1791(7):679-83. PubMed ID: 19272334
[TBL] [Abstract][Full Text] [Related]
3. Deficiency of Niemann-Pick C1 Like 1 prevents atherosclerosis in ApoE-/- mice.
Davis HR; Hoos LM; Tetzloff G; Maguire M; Zhu LJ; Graziano MP; Altmann SW
Arterioscler Thromb Vasc Biol; 2007 Apr; 27(4):841-9. PubMed ID: 17218600
[TBL] [Abstract][Full Text] [Related]
4. Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption.
Altmann SW; Davis HR; Zhu LJ; Yao X; Hoos LM; Tetzloff G; Iyer SP; Maguire M; Golovko A; Zeng M; Wang L; Murgolo N; Graziano MP
Science; 2004 Feb; 303(5661):1201-4. PubMed ID: 14976318
[TBL] [Abstract][Full Text] [Related]
5. Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.
Davis HR; Zhu LJ; Hoos LM; Tetzloff G; Maguire M; Liu J; Yao X; Iyer SP; Lam MH; Lund EG; Detmers PA; Graziano MP; Altmann SW
J Biol Chem; 2004 Aug; 279(32):33586-92. PubMed ID: 15173162
[TBL] [Abstract][Full Text] [Related]
6. The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1.
Ge L; Wang J; Qi W; Miao HH; Cao J; Qu YX; Li BL; Song BL
Cell Metab; 2008 Jun; 7(6):508-19. PubMed ID: 18522832
[TBL] [Abstract][Full Text] [Related]
7. Niemann-pick C1-like 1 mediates alpha-tocopherol transport.
Narushima K; Takada T; Yamanashi Y; Suzuki H
Mol Pharmacol; 2008 Jul; 74(1):42-9. PubMed ID: 18403720
[TBL] [Abstract][Full Text] [Related]
8. Zetia: inhibition of Niemann-Pick C1 Like 1 (NPC1L1) to reduce intestinal cholesterol absorption and treat hyperlipidemia.
Davis HR; Veltri EP
J Atheroscler Thromb; 2007 Jun; 14(3):99-108. PubMed ID: 17587760
[TBL] [Abstract][Full Text] [Related]
9. Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport.
Jia L; Betters JL; Yu L
Annu Rev Physiol; 2011; 73():239-59. PubMed ID: 20809793
[TBL] [Abstract][Full Text] [Related]
10. Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like 1 only in liver.
Tang W; Jia L; Ma Y; Xie P; Haywood J; Dawson PA; Li J; Yu L
Biochim Biophys Acta; 2011 Sep; 1811(9):549-55. PubMed ID: 21683156
[TBL] [Abstract][Full Text] [Related]
11. Niemann-Pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells.
Yamanashi Y; Takada T; Suzuki H
J Pharmacol Exp Ther; 2007 Feb; 320(2):559-64. PubMed ID: 17135346
[TBL] [Abstract][Full Text] [Related]
12. Ezetimibe inhibits hepatic Niemann-Pick C1-Like 1 to facilitate macrophage reverse cholesterol transport in mice.
Xie P; Jia L; Ma Y; Ou J; Miao H; Wang N; Guo F; Yazdanyar A; Jiang XC; Yu L
Arterioscler Thromb Vasc Biol; 2013 May; 33(5):920-5. PubMed ID: 23471229
[TBL] [Abstract][Full Text] [Related]
13. Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane.
Knöpfel M; Davies JP; Duong PT; Kvaernø L; Carreira EM; Phillips MC; Ioannou YA; Hauser H
Biochim Biophys Acta; 2007 Sep; 1771(9):1140-7. PubMed ID: 17689140
[TBL] [Abstract][Full Text] [Related]
14. Hepatic Niemann-Pick C1-like 1.
Pramfalk C; Jiang ZY; Parini P
Curr Opin Lipidol; 2011 Jun; 22(3):225-30. PubMed ID: 21494140
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of intestinal cholesterol absorption by ezetimibe is a novel therapeutic target for fatty liver.
Yamagishi S; Nakamura K; Matsui T; Sato T; Takeuchi M
Med Hypotheses; 2006; 66(4):844-6. PubMed ID: 16188393
[TBL] [Abstract][Full Text] [Related]
16. In vivo responsiveness to ezetimibe correlates with niemann-pick C1 like-1 (NPC1L1) binding affinity: Comparison of multiple species NPC1L1 orthologs.
Hawes BE; O'neill KA; Yao X; Crona JH; Davis HR; Graziano MP; Altmann SW
Mol Pharmacol; 2007 Jan; 71(1):19-29. PubMed ID: 17005902
[TBL] [Abstract][Full Text] [Related]
17. Use of NBD-cholesterol to identify a minor but NPC1L1-independent cholesterol absorption pathway in mouse intestine.
Adams MR; Konaniah E; Cash JG; Hui DY
Am J Physiol Gastrointest Liver Physiol; 2011 Jan; 300(1):G164-9. PubMed ID: 21071508
[TBL] [Abstract][Full Text] [Related]
18. Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe.
Temel RE; Tang W; Ma Y; Rudel LL; Willingham MC; Ioannou YA; Davies JP; Nilsson LM; Yu L
J Clin Invest; 2007 Jul; 117(7):1968-78. PubMed ID: 17571164
[TBL] [Abstract][Full Text] [Related]
19. Respective contributions of intestinal Niemann-Pick C1-like 1 and scavenger receptor class B type I to cholesterol and tocopherol uptake: in vivo v. in vitro studies.
Reboul E; Soayfane Z; Goncalves A; Cantiello M; Bott R; Nauze M; Tercé F; Collet X; Coméra C
Br J Nutr; 2012 May; 107(9):1296-304. PubMed ID: 21929836
[TBL] [Abstract][Full Text] [Related]
20. Genetic demonstration of intestinal NPC1L1 as a major determinant of hepatic cholesterol and blood atherogenic lipoprotein levels.
Xie P; Zhu H; Jia L; Ma Y; Tang W; Wang Y; Xue B; Shi H; Yu L
Atherosclerosis; 2014 Dec; 237(2):609-17. PubMed ID: 25463095
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]