BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 18586679)

  • 1. Interleukin-3 (IL-3)-induced c-fos activation is modulated by Gab2-calcineurin interaction.
    Pyarajan S; Matejovic G; Pratt JC; Baksh S; Burakoff SJ
    J Biol Chem; 2008 Aug; 283(35):23505-9. PubMed ID: 18586679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of a leukemia-associated gain-of-function mutation of SHP-2 phosphatase on interleukin-3 signaling.
    Yu WM; Daino H; Chen J; Bunting KD; Qu CK
    J Biol Chem; 2006 Mar; 281(9):5426-34. PubMed ID: 16371368
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit.
    Sun J; Pedersen M; Rönnstrand L
    J Biol Chem; 2008 Oct; 283(41):27444-27451. PubMed ID: 18697750
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G-CSF-induced tyrosine phosphorylation of Gab2 is Lyn kinase dependent and associated with enhanced Akt and differentiative, not proliferative, responses.
    Zhu QS; Robinson LJ; Roginskaya V; Corey SJ
    Blood; 2004 May; 103(9):3305-12. PubMed ID: 14656892
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells.
    Caron C; Spring K; Laramée M; Chabot C; Cloutier M; Gu H; Royal I
    Cell Signal; 2009 Jun; 21(6):943-53. PubMed ID: 19233262
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Defibrotide Stimulates Angiogenesis and Protects Endothelial Cells from Calcineurin Inhibitor-Induced Apoptosis via Upregulation of AKT/Bcl-xL.
    Wang X; Pan B; Hashimoto Y; Ohkawara H; Xu K; Zeng L; Ikezoe T
    Thromb Haemost; 2018 Jan; 118(1):161-173. PubMed ID: 29304536
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The docking molecule gab2 is induced by lymphocyte activation and is involved in signaling by interleukin-2 and interleukin-15 but not other common gamma chain-using cytokines.
    Gadina M; Sudarshan C; Visconti R; Zhou YJ; Gu H; Neel BG; O'Shea JJ
    J Biol Chem; 2000 Sep; 275(35):26959-66. PubMed ID: 10849428
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells.
    Podar K; Mostoslavsky G; Sattler M; Tai YT; Hayashi T; Catley LP; Hideshima T; Mulligan RC; Chauhan D; Anderson KC
    J Biol Chem; 2004 May; 279(20):21658-65. PubMed ID: 15010462
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.
    Yamasaki S; Nishida K; Hibi M; Sakuma M; Shiina R; Takeuchi A; Ohnishi H; Hirano T; Saito T
    J Biol Chem; 2001 Nov; 276(48):45175-83. PubMed ID: 11572860
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death.
    Tosello V; Saccomani V; Yu J; Bordin F; Amadori A; Piovan E
    Oncotarget; 2016 Jul; 7(29):45715-45729. PubMed ID: 27304189
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter.
    Nyga R; Pecquet C; Harir N; Gu H; Dhennin-Duthille I; Régnier A; Gouilleux-Gruart V; Lassoued K; Gouilleux F
    Biochem J; 2005 Aug; 390(Pt 1):359-66. PubMed ID: 15833084
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation.
    Arnaud M; Crouin C; Deon C; Loyaux D; Bertoglio J
    J Immunol; 2004 Sep; 173(6):3962-71. PubMed ID: 15356145
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors.
    Nishida K; Yoshida Y; Itoh M; Fukada T; Ohtani T; Shirogane T; Atsumi T; Takahashi-Tezuka M; Ishihara K; Hibi M; Hirano T
    Blood; 1999 Mar; 93(6):1809-16. PubMed ID: 10068651
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells.
    Xie ZH; Ambudkar I; Siraganian RP
    J Immunol; 2002 May; 168(9):4682-91. PubMed ID: 11971018
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Signalling mechanisms and the role of calcineurin in erythropoiesis.
    Magócsi M; Apáti A; Gáti R; Kolonics A
    Immunol Lett; 1999 May; 68(1):187-95. PubMed ID: 10397175
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2.
    Lynch DK; Daly RJ
    EMBO J; 2002 Jan; 21(1-2):72-82. PubMed ID: 11782427
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.
    Shi Y; Hsu JH; Hu L; Gera J; Lichtenstein A
    J Biol Chem; 2002 May; 277(18):15712-20. PubMed ID: 11872747
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase.
    Liu Y; Jenkins B; Shin JL; Rohrschneider LR
    Mol Cell Biol; 2001 May; 21(9):3047-56. PubMed ID: 11287610
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death.
    Kim MJ; Jo DG; Hong GS; Kim BJ; Lai M; Cho DH; Kim KW; Bandyopadhyay A; Hong YM; Kim DH; Cho C; Liu JO; Snyder SH; Jung YK
    Proc Natl Acad Sci U S A; 2002 Jul; 99(15):9870-5. PubMed ID: 12114545
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphoinositide 3-kinase-dependent regulation of interleukin-3-induced proliferation: involvement of mitogen-activated protein kinases, SHP2 and Gab2.
    Craddock BL; Hobbs J; Edmead CE; Welham MJ
    J Biol Chem; 2001 Jun; 276(26):24274-83. PubMed ID: 11335710
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.