These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1312 related articles for article (PubMed ID: 18587408)

  • 1. Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase.
    Faghihi MA; Modarresi F; Khalil AM; Wood DE; Sahagan BG; Morgan TE; Finch CE; St Laurent G; Kenny PJ; Wahlestedt C
    Nat Med; 2008 Jul; 14(7):723-30. PubMed ID: 18587408
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Attenuated ability of BACE1 to cleave the amyloid precursor protein via silencing long noncoding RNA BACE1‑AS expression.
    Liu T; Huang Y; Chen J; Chi H; Yu Z; Wang J; Chen C
    Mol Med Rep; 2014 Sep; 10(3):1275-81. PubMed ID: 24970022
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence for natural antisense transcript-mediated inhibition of microRNA function.
    Faghihi MA; Zhang M; Huang J; Modarresi F; Van der Brug MP; Nalls MA; Cookson MR; St-Laurent G; Wahlestedt C
    Genome Biol; 2010; 11(5):R56. PubMed ID: 20507594
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered amyloid-beta metabolism and deposition in genomic-based beta-secretase transgenic mice.
    Chiocco MJ; Kulnane LS; Younkin L; Younkin S; Evin G; Lamb BT
    J Biol Chem; 2004 Dec; 279(50):52535-42. PubMed ID: 15452128
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BACE1-AS prevents BACE1 mRNA degradation through the sequestration of BACE1-targeting miRNAs.
    Zeng T; Ni H; Yu Y; Zhang M; Wu M; Wang Q; Wang L; Xu S; Xu Z; Xu C; Xiong J; Jiang J; Luo Y; Wang Y; Liu H
    J Chem Neuroanat; 2019 Jul; 98():87-96. PubMed ID: 30959172
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.
    Jo DG; Arumugam TV; Woo HN; Park JS; Tang SC; Mughal M; Hyun DH; Park JH; Choi YH; Gwon AR; Camandola S; Cheng A; Cai H; Song W; Markesbery WR; Mattson MP
    Neurobiol Aging; 2010 Jun; 31(6):917-25. PubMed ID: 18687504
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulatory RNA goes awry in Alzheimer's disease.
    St George-Hyslop P; Haass C
    Nat Med; 2008 Jul; 14(7):711-2. PubMed ID: 18607365
    [No Abstract]   [Full Text] [Related]  

  • 9. Increased BACE1-AS long noncoding RNA and β-amyloid levels in heart failure.
    Greco S; Zaccagnini G; Fuschi P; Voellenkle C; Carrara M; Sadeghi I; Bearzi C; Maimone B; Castelvecchio S; Stellos K; Gaetano C; Menicanti L; Martelli F
    Cardiovasc Res; 2017 Apr; 113(5):453-463. PubMed ID: 28158647
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.
    Kurkinen KM; Marttinen M; Turner L; Natunen T; Mäkinen P; Haapalinna F; Sarajärvi T; Gabbouj S; Kurki M; Paananen J; Koivisto AM; Rauramaa T; Leinonen V; Tanila H; Soininen H; Lucas FR; Haapasalo A; Hiltunen M
    J Cell Sci; 2016 Jun; 129(11):2224-38. PubMed ID: 27084579
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.
    O'Connor T; Sadleir KR; Maus E; Velliquette RA; Zhao J; Cole SL; Eimer WA; Hitt B; Bembinster LA; Lammich S; Lichtenthaler SF; Hébert SS; De Strooper B; Haass C; Bennett DA; Vassar R
    Neuron; 2008 Dec; 60(6):988-1009. PubMed ID: 19109907
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The effect of BACE1-AS on β-amyloid generation by regulating BACE1 mRNA expression.
    Li F; Wang Y; Yang H; Xu Y; Zhou X; Zhang X; Xie Z; Bi J
    BMC Mol Biol; 2019 Oct; 20(1):23. PubMed ID: 31570097
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BACE1 in Alzheimer's disease.
    Sathya M; Premkumar P; Karthick C; Moorthi P; Jayachandran KS; Anusuyadevi M
    Clin Chim Acta; 2012 Dec; 414():171-8. PubMed ID: 22926063
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells.
    Marwarha G; Raza S; Prasanthi JR; Ghribi O
    PLoS One; 2013; 8(8):e70773. PubMed ID: 23951005
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.
    Marwarha G; Rostad S; Lilek J; Kleinjan M; Schommer J; Ghribi O
    J Alzheimers Dis; 2017; 57(3):907-925. PubMed ID: 28304295
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
    Chen LM; Lin ZY; Zhu YG; Lin N; Zhang J; Pan XD; Chen XC
    Eur J Pharmacol; 2012 Jan; 675(1-3):15-21. PubMed ID: 22166376
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The β-Secretase Enzyme BACE1: A Biochemical Enigma for Alzheimer's Disease.
    Shah H; Patel A; Parikh V; Nagani A; Bhimani B; Shah U; Bambharoliya T
    CNS Neurol Disord Drug Targets; 2020; 19(3):184-194. PubMed ID: 32452328
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models.
    Bahn G; Park JS; Yun UJ; Lee YJ; Choi Y; Park JS; Baek SH; Choi BY; Cho YS; Kim HK; Han J; Sul JH; Baik SH; Lim J; Wakabayashi N; Bae SH; Han JW; Arumugam TV; Mattson MP; Jo DG
    Proc Natl Acad Sci U S A; 2019 Jun; 116(25):12516-12523. PubMed ID: 31164420
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 66.