These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 18588280)

  • 1. Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors.
    Liou JP; Wu ZY; Kuo CC; Chang CY; Lu PY; Chen CM; Hsieh HP; Chang JY
    J Med Chem; 2008 Jul; 51(14):4351-5. PubMed ID: 18588280
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
    J Med Chem; 2007 Sep; 50(18):4548-52. PubMed ID: 17685504
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents.
    Liou JP; Chang YL; Kuo FM; Chang CW; Tseng HY; Wang CC; Yang YN; Chang JY; Lee SJ; Hsieh HP
    J Med Chem; 2004 Aug; 47(17):4247-57. PubMed ID: 15293996
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors.
    Nien CY; Chen YC; Kuo CC; Hsieh HP; Chang CY; Wu JS; Wu SY; Liou JP; Chang JY
    J Med Chem; 2010 Mar; 53(5):2309-13. PubMed ID: 20148562
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Arylthioindoles, potent inhibitors of tubulin polymerization.
    De Martino G; La Regina G; Coluccia A; Edler MC; Barbera MC; Brancale A; Wilcox E; Hamel E; Artico M; Silvestri R
    J Med Chem; 2004 Dec; 47(25):6120-3. PubMed ID: 15566282
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents.
    Chang JY; Hsieh HP; Chang CY; Hsu KS; Chiang YF; Chen CM; Kuo CC; Liou JP
    J Med Chem; 2006 Nov; 49(23):6656-9. PubMed ID: 17154496
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents.
    Reddy GR; Kuo CC; Tan UK; Coumar MS; Chang CY; Chiang YK; Lai MJ; Yeh JY; Wu SY; Chang JY; Liou JP; Hsieh HP
    J Med Chem; 2008 Dec; 51(24):8163-7. PubMed ID: 19053773
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of 1-(4'-Indolyl and 6'-Quinolinyl) indoles as a new class of potent anticancer agents.
    Lai MJ; Chang JY; Lee HY; Kuo CC; Lin MH; Hsieh HP; Chang CY; Wu JS; Wu SY; Shey KS; Liou JP
    Eur J Med Chem; 2011 Sep; 46(9):3623-9. PubMed ID: 21641700
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of tubulin polymerization by 5,6-dihydroindolo[2,1-alpha]isoquinoline derivatives.
    Goldbrunner M; Loidl G; Polossek T; Mannschreck A; von Angerer E
    J Med Chem; 1997 Oct; 40(22):3524-33. PubMed ID: 9357519
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.
    La Regina G; Edler MC; Brancale A; Kandil S; Coluccia A; Piscitelli F; Hamel E; De Martino G; Matesanz R; Díaz JF; Scovassi AI; Prosperi E; Lavecchia A; Novellino E; Artico M; Silvestri R
    J Med Chem; 2007 Jun; 50(12):2865-74. PubMed ID: 17497841
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stereoselective synthesis of 3,3-diarylacrylonitriles as tubulin polymerization inhibitors.
    Fang Z; Song Y; Sarkar T; Hamel E; Fogler WE; Agoston GE; Fanwick PE; Cushman M
    J Org Chem; 2008 Jun; 73(11):4241-4. PubMed ID: 18447388
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY; Yang MF; Chang CY; Chen CM; Kuo CC; Liou JP
    J Med Chem; 2006 Oct; 49(21):6412-5. PubMed ID: 17034147
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Indole, a core nucleus for potent inhibitors of tubulin polymerization.
    Brancale A; Silvestri R
    Med Res Rev; 2007 Mar; 27(2):209-38. PubMed ID: 16788980
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
    Chiang YK; Kuo CC; Wu YS; Chen CT; Coumar MS; Wu JS; Hsieh HP; Chang CY; Jseng HY; Wu MH; Leou JS; Song JS; Chang JY; Lyu PC; Chao YS; Wu SY
    J Med Chem; 2009 Jul; 52(14):4221-33. PubMed ID: 19507860
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New C5-alkylated indolobenzazepinones acting as inhibitors of tubulin polymerization: cytotoxic and antitumor activities.
    Keller L; Beaumont S; Liu JM; Thoret S; Bignon JS; Wdzieczak-Bakala J; Dauban P; Dodd RH
    J Med Chem; 2008 Jun; 51(12):3414-21. PubMed ID: 18503262
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation.
    Borrel C; Thoret S; Cachet X; Guénard D; Tillequin F; Koch M; Michel S
    Bioorg Med Chem; 2005 Jun; 13(11):3853-64. PubMed ID: 15863010
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents.
    Mahboobi S; Pongratz H; Hufsky H; Hockemeyer J; Frieser M; Lyssenko A; Paper DH; Bürgermeister J; Böhmer FD; Fiebig HH; Burger AM; Baasner S; Beckers T
    J Med Chem; 2001 Dec; 44(26):4535-53. PubMed ID: 11741473
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of analogs of 2-methoxyestradiol with enhanced inhibitory effects on tubulin polymerization and cancer cell growth.
    Cushman M; He HM; Katzenellenbogen JA; Varma RK; Hamel E; Lin CM; Ram S; Sachdeva YP
    J Med Chem; 1997 Jul; 40(15):2323-34. PubMed ID: 9240348
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
    Ouyang X; Piatnitski EL; Pattaropong V; Chen X; He HY; Kiselyov AS; Velankar A; Kawakami J; Labelle M; Smith L; Lohman J; Lee SP; Malikzay A; Fleming J; Gerlak J; Wang Y; Rosler RL; Zhou K; Mitelman S; Camara M; Surguladze D; Doody JF; Tuma MC
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1191-6. PubMed ID: 16377187
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies.
    De Martino G; Edler MC; La Regina G; Coluccia A; Barbera MC; Barrow D; Nicholson RI; Chiosis G; Brancale A; Hamel E; Artico M; Silvestri R
    J Med Chem; 2006 Feb; 49(3):947-54. PubMed ID: 16451061
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.