These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 18590687)

  • 1. The double life of Irs.
    Haeusler RA; Accili D
    Cell Metab; 2008 Jul; 8(1):7-9. PubMed ID: 18590687
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.
    Kubota N; Kubota T; Itoh S; Kumagai H; Kozono H; Takamoto I; Mineyama T; Ogata H; Tokuyama K; Ohsugi M; Sasako T; Moroi M; Sugi K; Kakuta S; Iwakura Y; Noda T; Ohnishi S; Nagai R; Tobe K; Terauchi Y; Ueki K; Kadowaki T
    Cell Metab; 2008 Jul; 8(1):49-64. PubMed ID: 18590692
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin receptor substrates 1 and 2 but not Shc can activate the insulin receptor independent of insulin and induce proliferation in CHO-IR cells.
    Niessen M; Jaschinski F; Item F; McNamara MP; Spinas GA; Trüb T
    Exp Cell Res; 2007 Feb; 313(4):805-15. PubMed ID: 17222824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice.
    Simmgen M; Knauf C; Lopez M; Choudhury AI; Charalambous M; Cantley J; Bedford DC; Claret M; Iglesias MA; Heffron H; Cani PD; Vidal-Puig A; Burcelin R; Withers DJ
    Diabetologia; 2006 Mar; 49(3):552-61. PubMed ID: 16404553
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling.
    Guo S; Dunn SL; White MF
    Mol Endocrinol; 2006 Dec; 20(12):3389-99. PubMed ID: 16916938
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Divergent Roles of IRS (Insulin Receptor Substrate) 1 and 2 in Liver and Skeletal Muscle.
    Eckstein SS; Weigert C; Lehmann R
    Curr Med Chem; 2017; 24(17):1827-1852. PubMed ID: 28462703
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation.
    Dong XC; Copps KD; Guo S; Li Y; Kollipara R; DePinho RA; White MF
    Cell Metab; 2008 Jul; 8(1):65-76. PubMed ID: 18590693
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3.
    Kawaguchi T; Yoshida T; Harada M; Hisamoto T; Nagao Y; Ide T; Taniguchi E; Kumemura H; Hanada S; Maeyama M; Baba S; Koga H; Kumashiro R; Ueno T; Ogata H; Yoshimura A; Sata M
    Am J Pathol; 2004 Nov; 165(5):1499-508. PubMed ID: 15509521
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth.
    Dong X; Park S; Lin X; Copps K; Yi X; White MF
    J Clin Invest; 2006 Jan; 116(1):101-14. PubMed ID: 16374520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice.
    Yamauchi T; Tobe K; Tamemoto H; Ueki K; Kaburagi Y; Yamamoto-Honda R; Takahashi Y; Yoshizawa F; Aizawa S; Akanuma Y; Sonenberg N; Yazaki Y; Kadowaki T
    Mol Cell Biol; 1996 Jun; 16(6):3074-84. PubMed ID: 8649419
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.
    Rui L; Yuan M; Frantz D; Shoelson S; White MF
    J Biol Chem; 2002 Nov; 277(44):42394-8. PubMed ID: 12228220
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin.
    Besse-Patin A; Jeromson S; Levesque-Damphousse P; Secco B; Laplante M; Estall JL
    Proc Natl Acad Sci U S A; 2019 Mar; 116(10):4285-4290. PubMed ID: 30770439
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects.
    Rametta R; Mozzi E; Dongiovanni P; Motta BM; Milano M; Roviaro G; Fargion S; Valenti L
    Int J Obes (Lond); 2013 Jul; 37(7):986-92. PubMed ID: 23147115
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Both insulin signaling defects in the liver and obesity contribute to insulin resistance and cause diabetes in Irs2(-/-) mice.
    Suzuki R; Tobe K; Aoyama M; Inoue A; Sakamoto K; Yamauchi T; Kamon J; Kubota N; Terauchi Y; Yoshimatsu H; Matsuhisa M; Nagasaka S; Ogata H; Tokuyama K; Nagai R; Kadowaki T
    J Biol Chem; 2004 Jun; 279(24):25039-49. PubMed ID: 15028732
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes.
    Valverde AM; Burks DJ; Fabregat I; Fisher TL; Carretero J; White MF; Benito M
    Diabetes; 2003 Sep; 52(9):2239-48. PubMed ID: 12941762
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Mig-6 in hepatic glucose metabolism.
    Yoo JY; Kim TH; Kong S; Lee JH; Choi W; Kim KS; Kim HJ; Jeong JW; Ku BJ
    J Diabetes; 2016 Jan; 8(1):86-97. PubMed ID: 25594850
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.
    Withers DJ; Burks DJ; Towery HH; Altamuro SL; Flint CL; White MF
    Nat Genet; 1999 Sep; 23(1):32-40. PubMed ID: 10471495
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells.
    Brüning JC; Winnay J; Cheatham B; Kahn CR
    Mol Cell Biol; 1997 Mar; 17(3):1513-21. PubMed ID: 9032279
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling.
    Canettieri G; Koo SH; Berdeaux R; Heredia J; Hedrick S; Zhang X; Montminy M
    Cell Metab; 2005 Nov; 2(5):331-8. PubMed ID: 16271533
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential.
    Giovannone B; Scaldaferri ML; Federici M; Porzio O; Lauro D; Fusco A; Sbraccia P; Borboni P; Lauro R; Sesti G
    Diabetes Metab Res Rev; 2000; 16(6):434-41. PubMed ID: 11114102
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.