129 related articles for article (PubMed ID: 18590959)
1. Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.
Khim SK; Bauman J; Evans J; Freeman B; King B; Kirkland T; Kochanny M; Lentz D; Liang A; Mendoza L; Phillips G; Tseng JL; Wei RG; Ye H; Yu L; Parkinson J; Guilford WJ
Bioorg Med Chem Lett; 2008 Jul; 18(14):3895-8. PubMed ID: 18590959
[TBL] [Abstract][Full Text] [Related]
2. Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase.
Ye B; Bauman J; Chen M; Davey D; Khim SK; King B; Kirkland T; Kochanny M; Liang A; Lentz D; May K; Mendoza L; Phillips G; Selchau V; Schlyer S; Tseng JL; Wei RG; Ye H; Parkinson J; Guilford WJ
Bioorg Med Chem Lett; 2008 Jul; 18(14):3891-4. PubMed ID: 18586492
[TBL] [Abstract][Full Text] [Related]
3. Activation and inhibition of leukotriene A4 hydrolase aminopeptidase activity by diphenyl ether and derivatives.
Jiang X; Zhou L; Wei D; Meng H; Liu Y; Lai L
Bioorg Med Chem Lett; 2008 Dec; 18(24):6549-52. PubMed ID: 18952425
[TBL] [Abstract][Full Text] [Related]
4. Identification and optimization of N3,N6-diaryl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamines as a novel class of ACK1 inhibitors.
Kopecky DJ; Hao X; Chen Y; Fu J; Jiao X; Jaen JC; Cardozo MG; Liu J; Wang Z; Walker NP; Wesche H; Li S; Farrelly E; Xiao SH; Kayser F
Bioorg Med Chem Lett; 2008 Dec; 18(24):6352-6. PubMed ID: 18993068
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase.
Pecic S; Deng SX; Morisseau C; Hammock BD; Landry DW
Bioorg Med Chem Lett; 2012 Jan; 22(1):601-5. PubMed ID: 22079754
[TBL] [Abstract][Full Text] [Related]
6. Discovery of novel leukotriene A4 hydrolase inhibitors based on piperidine and piperazine scaffolds.
Sandanayaka V; Mamat B; Bhagat N; Bedell L; Halldorsdottir G; Sigthorsdottir H; Andrésson T; Kiselyov A; Gurney M; Singh J
Bioorg Med Chem Lett; 2010 May; 20(9):2851-4. PubMed ID: 20371179
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of N-mercaptoacylproline and N-mercaptoacylthiazolidine-4-carboxylic acid derivatives as leukotriene A4 hydrolase inhibitors.
Enomoto H; Morikawa Y; Miyake Y; Tsuji F; Mizuchi M; Suhara H; Fujimura K; Horiuchi M; Ban M
Bioorg Med Chem Lett; 2008 Aug; 18(16):4529-32. PubMed ID: 18674901
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase.
Jones PD; Tsai HJ; Do ZN; Morisseau C; Hammock BD
Bioorg Med Chem Lett; 2006 Oct; 16(19):5212-6. PubMed ID: 16870439
[TBL] [Abstract][Full Text] [Related]
9. Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Grice CA; Tays KL; Savall BM; Wei J; Butler CR; Axe FU; Bembenek SD; Fourie AM; Dunford PJ; Lundeen K; Coles F; Xue X; Riley JP; Williams KN; Karlsson L; Edwards JP
J Med Chem; 2008 Jul; 51(14):4150-69. PubMed ID: 18588282
[TBL] [Abstract][Full Text] [Related]
10. Discovery of dual target inhibitors against cyclooxygenases and leukotriene A4 hydrolyase.
Chen Z; Wu Y; Liu Y; Yang S; Chen Y; Lai L
J Med Chem; 2011 May; 54(10):3650-60. PubMed ID: 21542630
[TBL] [Abstract][Full Text] [Related]
11. Unsymmetrical non-adamantyl N,N'-diaryl urea and amide inhibitors of soluble expoxide hydrolase.
Anandan SK; Webb HK; Do ZN; Gless RD
Bioorg Med Chem Lett; 2009 Aug; 19(15):4259-63. PubMed ID: 19520575
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase.
Penning TD; Chandrakumar NS; Desai BN; Djuric SW; Gasiecki AF; Malecha JW; Miyashiro JM; Russell MA; Askonas LJ; Gierse JK; Harding EI; Highkin MK; Kachur JF; Kim SH; Villani-Price D; Pyla EY; Ghoreishi-Haack NS; Smith WG
Bioorg Med Chem Lett; 2003 Mar; 13(6):1137-9. PubMed ID: 12643929
[TBL] [Abstract][Full Text] [Related]
13. Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase.
Penning TD; Chandrakumar NS; Desai BN; Djuric SW; Gasiecki AF; Liang CD; Miyashiro JM; Russell MA; Askonas LJ; Gierse JK; Harding EI; Highkin MK; Kachur JF; Kim SH; Villani-Price D; Pyla EY; Ghoreishi-Haack NS; Smith WG
Bioorg Med Chem Lett; 2002 Dec; 12(23):3383-6. PubMed ID: 12419366
[TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of substituted nicotinamides as inhibitors of soluble epoxide hydrolase.
Taylor SJ; Soleymanzadeh F; Eldrup AB; Farrow NA; Muegge I; Kukulka A; Kabcenell AK; De Lombaert S
Bioorg Med Chem Lett; 2009 Oct; 19(20):5864-8. PubMed ID: 19758802
[TBL] [Abstract][Full Text] [Related]
15. Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors.
Calışkan B; Banoglu E
Expert Opin Drug Discov; 2013 Jan; 8(1):49-63. PubMed ID: 23095029
[TBL] [Abstract][Full Text] [Related]
16. Thermodynamic properties of leukotriene A
Wittmann SK; Kalinowsky L; Kramer JS; Bloecher R; Knapp S; Steinhilber D; Pogoryelov D; Proschak E; Heering J
Bioorg Med Chem; 2016 Nov; 24(21):5243-5248. PubMed ID: 27651294
[TBL] [Abstract][Full Text] [Related]
17. The identification of pyrazolo[1,5-a]pyridines as potent p38 kinase inhibitors.
Cheung M; Harris PA; Badiang JG; Peckham GE; Chamberlain SD; Alberti MJ; Jung DK; Harris SS; Bramson NH; Epperly AH; Stimpson SA; Peel MR
Bioorg Med Chem Lett; 2008 Oct; 18(20):5428-30. PubMed ID: 18818075
[TBL] [Abstract][Full Text] [Related]
18. Azabenzthiazole inhibitors of leukotriene A₄ hydrolase.
Tanis VM; Bacani GM; Blevitt JM; Chrovian CC; Crawford S; De Leon A; Fourie AM; Gomez L; Grice CA; Herman K; Kearney AM; Landry-Bayle AM; Lee-Dutra A; Nelson J; Riley JP; Santillán A; Wiener JJ; Xue X; Young AL
Bioorg Med Chem Lett; 2012 Dec; 22(24):7504-11. PubMed ID: 23127888
[TBL] [Abstract][Full Text] [Related]
19. Salicylate-urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities.
Kasagami T; Kim IH; Tsai HJ; Nishi K; Hammock BD; Morisseau C
Bioorg Med Chem Lett; 2009 Mar; 19(6):1784-9. PubMed ID: 19216074
[TBL] [Abstract][Full Text] [Related]
20. Development of selective tight-binding inhibitors of leukotriene A4 hydrolase.
Yuan W; Munoz B; Wong CH; Haeggström JZ; Wetterholm A; Samuelsson B
J Med Chem; 1993 Jan; 36(2):211-20. PubMed ID: 8423594
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
