These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
184 related articles for article (PubMed ID: 18591263)
1. Mechanisms of human immunodeficiency virus type 1 concerted integration related to strand transfer inhibition and drug resistance. Zahm JA; Bera S; Pandey KK; Vora A; Stillmock K; Hazuda D; Grandgenett DP Antimicrob Agents Chemother; 2008 Sep; 52(9):3358-68. PubMed ID: 18591263 [TBL] [Abstract][Full Text] [Related]
2. Inhibition of human immunodeficiency virus type 1 concerted integration by strand transfer inhibitors which recognize a transient structural intermediate. Pandey KK; Bera S; Zahm J; Vora A; Stillmock K; Hazuda D; Grandgenett DP J Virol; 2007 Nov; 81(22):12189-99. PubMed ID: 17804497 [TBL] [Abstract][Full Text] [Related]
3. Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations. Fikkert V; Van Maele B; Vercammen J; Hantson A; Van Remoortel B; Michiels M; Gurnari C; Pannecouque C; De Maeyer M; Engelborghs Y; De Clercq E; Debyser Z; Witvrouw M J Virol; 2003 Nov; 77(21):11459-70. PubMed ID: 14557631 [TBL] [Abstract][Full Text] [Related]
4. Mutations in human immunodeficiency virus type 1 integrase confer resistance to the naphthyridine L-870,810 and cross-resistance to the clinical trial drug GS-9137. Hombrouck A; Voet A; Van Remoortel B; Desadeleer C; De Maeyer M; Debyser Z; Witvrouw M Antimicrob Agents Chemother; 2008 Jun; 52(6):2069-78. PubMed ID: 18378713 [TBL] [Abstract][Full Text] [Related]
5. The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral. Garvey EP; Johns BA; Gartland MJ; Foster SA; Miller WH; Ferris RG; Hazen RJ; Underwood MR; Boros EE; Thompson JB; Weatherhead JG; Koble CS; Allen SH; Schaller LT; Sherrill RG; Yoshinaga T; Kobayashi M; Wakasa-Morimoto C; Miki S; Nakahara K; Noshi T; Sato A; Fujiwara T Antimicrob Agents Chemother; 2008 Mar; 52(3):901-8. PubMed ID: 18160521 [TBL] [Abstract][Full Text] [Related]
6. A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase. Hazuda DJ; Anthony NJ; Gomez RP; Jolly SM; Wai JS; Zhuang L; Fisher TE; Embrey M; Guare JP; Egbertson MS; Vacca JP; Huff JR; Felock PJ; Witmer MV; Stillmock KA; Danovich R; Grobler J; Miller MD; Espeseth AS; Jin L; Chen IW; Lin JH; Kassahun K; Ellis JD; Wong BK; Xu W; Pearson PG; Schleif WA; Cortese R; Emini E; Summa V; Holloway MK; Young SD Proc Natl Acad Sci U S A; 2004 Aug; 101(31):11233-8. PubMed ID: 15277684 [TBL] [Abstract][Full Text] [Related]
7. In Vitro antiretroviral properties of S/GSK1349572, a next-generation HIV integrase inhibitor. Kobayashi M; Yoshinaga T; Seki T; Wakasa-Morimoto C; Brown KW; Ferris R; Foster SA; Hazen RJ; Miki S; Suyama-Kagitani A; Kawauchi-Miki S; Taishi T; Kawasuji T; Johns BA; Underwood MR; Garvey EP; Sato A; Fujiwara T Antimicrob Agents Chemother; 2011 Feb; 55(2):813-21. PubMed ID: 21115794 [TBL] [Abstract][Full Text] [Related]
8. Selection and analysis of HIV-1 integrase strand transfer inhibitor resistant mutant viruses. Witmer M; Danovich R Methods; 2009 Apr; 47(4):277-82. PubMed ID: 19286458 [TBL] [Abstract][Full Text] [Related]
9. Human immunodeficiency virus type 1 (HIV-1) integrase: resistance to diketo acid integrase inhibitors impairs HIV-1 replication and integration and confers cross-resistance to L-chicoric acid. Lee DJ; Robinson WE J Virol; 2004 Jun; 78(11):5835-47. PubMed ID: 15140981 [TBL] [Abstract][Full Text] [Related]
10. Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells. Hazuda DJ; Felock P; Witmer M; Wolfe A; Stillmock K; Grobler JA; Espeseth A; Gabryelski L; Schleif W; Blau C; Miller MD Science; 2000 Jan; 287(5453):646-50. PubMed ID: 10649997 [TBL] [Abstract][Full Text] [Related]
11. Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro. Malet I; Delelis O; Valantin MA; Montes B; Soulie C; Wirden M; Tchertanov L; Peytavin G; Reynes J; Mouscadet JF; Katlama C; Calvez V; Marcelin AG Antimicrob Agents Chemother; 2008 Apr; 52(4):1351-8. PubMed ID: 18227187 [TBL] [Abstract][Full Text] [Related]
12. HIV-1 integrase strand transfer inhibitors stabilize an integrase-single blunt-ended DNA complex. Bera S; Pandey KK; Vora AC; Grandgenett DP J Mol Biol; 2011 Jul; 410(5):831-46. PubMed ID: 21295584 [TBL] [Abstract][Full Text] [Related]
13. Dolutegravir-Selected HIV-1 Containing the N155H and R263K Resistance Substitutions Does Not Acquire Additional Compensatory Mutations under Drug Pressure That Lead to Higher-Level Resistance and Increased Replicative Capacity. Anstett K; Fusco R; Cutillas V; Mesplède T; Wainberg MA J Virol; 2015 Oct; 89(20):10482-8. PubMed ID: 26246578 [TBL] [Abstract][Full Text] [Related]
14. Dihydroxythiophenes are novel potent inhibitors of human immunodeficiency virus integrase with a diketo acid-like pharmacophore. Kehlenbeck S; Betz U; Birkmann A; Fast B; Göller AH; Henninger K; Lowinger T; Marrero D; Paessens A; Paulsen D; Pevzner V; Schohe-Loop R; Tsujishita H; Welker R; Kreuter J; Rübsamen-Waigmann H; Dittmer F J Virol; 2006 Jul; 80(14):6883-94. PubMed ID: 16809294 [TBL] [Abstract][Full Text] [Related]
15. Mutations Located outside the Integrase Gene Can Confer Resistance to HIV-1 Integrase Strand Transfer Inhibitors. Malet I; Subra F; Charpentier C; Collin G; Descamps D; Calvez V; Marcelin AG; Delelis O mBio; 2017 Sep; 8(5):. PubMed ID: 28951475 [TBL] [Abstract][Full Text] [Related]
16. Biochemical analysis of HIV-1 integrase variants resistant to strand transfer inhibitors. Dicker IB; Terry B; Lin Z; Li Z; Bollini S; Samanta HK; Gali V; Walker MA; Krystal MR J Biol Chem; 2008 Aug; 283(35):23599-609. PubMed ID: 18577511 [TBL] [Abstract][Full Text] [Related]
17. Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions. Svarovskaia ES; Barr R; Zhang X; Pais GC; Marchand C; Pommier Y; Burke TR; Pathak VK J Virol; 2004 Apr; 78(7):3210-22. PubMed ID: 15016842 [TBL] [Abstract][Full Text] [Related]
18. Mode of interaction of G-quartets with the integrase of human immunodeficiency virus type 1. Cherepanov P; Esté JA; Rando RF; Ojwang JO; Reekmans G; Steinfeld R; David G; De Clercq E; Debyser Z Mol Pharmacol; 1997 Nov; 52(5):771-80. PubMed ID: 9351967 [TBL] [Abstract][Full Text] [Related]
19. Resistance to inhibitors of the human immunodeficiency virus type 1 integration. Hazuda DJ Braz J Infect Dis; 2010; 14(5):513-8. PubMed ID: 21221483 [TBL] [Abstract][Full Text] [Related]
20. Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors. Zhao XZ; Smith SJ; Maskell DP; Métifiot M; Pye VE; Fesen K; Marchand C; Pommier Y; Cherepanov P; Hughes SH; Burke TR J Med Chem; 2017 Sep; 60(17):7315-7332. PubMed ID: 28737946 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]