BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

651 related articles for article (PubMed ID: 18593899)

  • 1. The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A.
    Guerrero-Santoro J; Kapetanaki MG; Hsieh CL; Gorbachinsky I; Levine AS; Rapić-Otrin V
    Cancer Res; 2008 Jul; 68(13):5014-22. PubMed ID: 18593899
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites.
    Kapetanaki MG; Guerrero-Santoro J; Bisi DC; Hsieh CL; Rapić-Otrin V; Levine AS
    Proc Natl Acad Sci U S A; 2006 Feb; 103(8):2588-93. PubMed ID: 16473935
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DNA-binding and cullin 4A ubiquitin ligase activity.
    Li J; Wang QE; Zhu Q; El-Mahdy MA; Wani G; Praetorius-Ibba M; Wani AA
    Cancer Res; 2006 Sep; 66(17):8590-7. PubMed ID: 16951172
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Monoubiquitinated histone H2A destabilizes photolesion-containing nucleosomes with concomitant release of UV-damaged DNA-binding protein E3 ligase.
    Lan L; Nakajima S; Kapetanaki MG; Hsieh CL; Fagerburg M; Thickman K; Rodriguez-Collazo P; Leuba SH; Levine AS; Rapić-Otrin V
    J Biol Chem; 2012 Apr; 287(15):12036-49. PubMed ID: 22334663
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex.
    Matsuda N; Azuma K; Saijo M; Iemura S; Hioki Y; Natsume T; Chiba T; Tanaka K; Tanaka K
    DNA Repair (Amst); 2005 May; 4(5):537-45. PubMed ID: 15811626
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair.
    Yeh JI; Levine AS; Du S; Chinte U; Ghodke H; Wang H; Shi H; Hsieh CL; Conway JF; Van Houten B; Rapić-Otrin V
    Proc Natl Acad Sci U S A; 2012 Oct; 109(41):E2737-46. PubMed ID: 22822215
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair.
    Gracheva E; Chitale S; Wilhelm T; Rapp A; Byrne J; Stadler J; Medina R; Cardoso MC; Richly H
    J Cell Biol; 2016 Apr; 213(2):185-200. PubMed ID: 27091446
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cellular concentrations of DDB2 regulate dynamic binding of DDB1 at UV-induced DNA damage.
    Alekseev S; Luijsterburg MS; Pines A; Geverts B; Mari PO; Giglia-Mari G; Lans H; Houtsmuller AB; Mullenders LH; Hoeijmakers JH; Vermeulen W
    Mol Cell Biol; 2008 Dec; 28(24):7402-13. PubMed ID: 18936169
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC.
    Luijsterburg MS; Goedhart J; Moser J; Kool H; Geverts B; Houtsmuller AB; Mullenders LH; Vermeulen W; van Driel R
    J Cell Sci; 2007 Aug; 120(Pt 15):2706-16. PubMed ID: 17635991
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.
    Takedachi A; Saijo M; Tanaka K
    Mol Cell Biol; 2010 Jun; 30(11):2708-23. PubMed ID: 20368362
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Damage-specific DNA binding protein 1 (DDB1): a protein with a wide range of functions.
    Iovine B; Iannella ML; Bevilacqua MA
    Int J Biochem Cell Biol; 2011 Dec; 43(12):1664-7. PubMed ID: 21959250
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognition by XPC.
    El-Mahdy MA; Zhu Q; Wang QE; Wani G; Prætorius-Ibba M; Wani AA
    J Biol Chem; 2006 May; 281(19):13404-13411. PubMed ID: 16527807
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase.
    Yang Y; He S; Wang Q; Li F; Kwak MJ; Chen S; O'Connell D; Zhang T; Pirooz SD; Jeon YH; Chimge NO; Frenkel B; Choi Y; Aldrovandi GM; Oh BH; Yuan Z; Liang C
    Mol Cell; 2016 May; 62(4):507-19. PubMed ID: 27203177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Xeroderma pigmentosum complementation group E protein (XPE/DDB2): purification of various complexes of XPE and analyses of their damaged DNA binding and putative DNA repair properties.
    Kulaksiz G; Reardon JT; Sancar A
    Mol Cell Biol; 2005 Nov; 25(22):9784-92. PubMed ID: 16260596
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The xeroderma pigmentosum group E gene product DDB2 activates nucleotide excision repair by regulating the level of p21Waf1/Cip1.
    Stoyanova T; Yoon T; Kopanja D; Mokyr MB; Raychaudhuri P
    Mol Cell Biol; 2008 Jan; 28(1):177-87. PubMed ID: 17967871
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA.
    Fei J; Kaczmarek N; Luch A; Glas A; Carell T; Naegeli H
    PLoS Biol; 2011 Oct; 9(10):e1001183. PubMed ID: 22039351
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.
    Groisman R; Polanowska J; Kuraoka I; Sawada J; Saijo M; Drapkin R; Kisselev AF; Tanaka K; Nakatani Y
    Cell; 2003 May; 113(3):357-67. PubMed ID: 12732143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage.
    Hu J; McCall CM; Ohta T; Xiong Y
    Nat Cell Biol; 2004 Oct; 6(10):1003-9. PubMed ID: 15448697
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Damage-specific DNA binding protein 1 (DDB1) is involved in ubiquitin-mediated proteolysis of p27Kip1 in response to UV irradiation.
    Iovine B; Iannella ML; Bevilacqua MA
    Biochimie; 2011 May; 93(5):867-75. PubMed ID: 21237244
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome.
    Bondar T; Kalinina A; Khair L; Kopanja D; Nag A; Bagchi S; Raychaudhuri P
    Mol Cell Biol; 2006 Apr; 26(7):2531-9. PubMed ID: 16537899
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.