153 related articles for article (PubMed ID: 18595758)
1. Selectivity-based QSAR approach for screening and evaluation of TRH analogs for TRH-R1 and TRH-R2 receptors subtypes.
Kadam RU; Chavan AG; Monga V; Kaur N; Jain R; Roy N
J Mol Graph Model; 2008 Oct; 27(3):309-20. PubMed ID: 18595758
[TBL] [Abstract][Full Text] [Related]
2. Thyrotropin-releasing hormone (TRH) analogues that exhibit selectivity to TRH receptor subtype 2.
Kaur N; Lu X; Gershengorn MC; Jain R
J Med Chem; 2005 Sep; 48(19):6162-5. PubMed ID: 16162016
[TBL] [Abstract][Full Text] [Related]
3. Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1.
Kaur N; Monga V; Lu X; Gershengorn MC; Jain R
Bioorg Med Chem; 2007 Jan; 15(1):433-43. PubMed ID: 17035026
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, receptor binding, and CNS pharmacological studies of new thyrotropin-releasing hormone (TRH) analogues.
Monga V; Meena CL; Rajput S; Pawar C; Sharma SS; Lu X; Gershengorn MC; Jain R
ChemMedChem; 2011 Mar; 6(3):531-43. PubMed ID: 21302359
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, receptor binding, and activation studies of N(1)-alkyl-L-histidine containing thyrotropin-releasing hormone (TRH) analogues.
Kaur N; Monga V; Josan JS; Lu X; Gershengorn MC; Jain R
Bioorg Med Chem; 2006 Sep; 14(17):5981-8. PubMed ID: 16735122
[TBL] [Abstract][Full Text] [Related]
6. A refined model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Experimental analysis and energy minimization of the complex between TRH and TRH receptor.
Perlman JH; Laakkonen LJ; Guarnieri F; Osman R; Gershengorn MC
Biochemistry; 1996 Jun; 35(24):7643-50. PubMed ID: 8672465
[TBL] [Abstract][Full Text] [Related]
7. Cloning of two thyrotropin-releasing hormone receptor subtypes from a lower vertebrate (Catostomus commersoni): functional expression, gene structure, and evolution.
Harder S; Dammann O; Buck F; Zwiers H; Lederis K; Richter D; Bruhn TO
Gen Comp Endocrinol; 2001 Nov; 124(2):236-45. PubMed ID: 11703088
[TBL] [Abstract][Full Text] [Related]
8. Thyrotropin releasing hormone analogs: a building block approach to the construction of tetracyclic peptidomimetics.
Chu W; Perlman JH; Gershengorn MC; Moeller KD
Bioorg Med Chem Lett; 1998 Nov; 8(21):3093-6. PubMed ID: 9873682
[TBL] [Abstract][Full Text] [Related]
9. Chemistry and biology of thyrotropin-releasing hormone (TRH) and its analogs.
Monga V; Meena CL; Kaur N; Jain R
Curr Med Chem; 2008; 15(26):2718-33. PubMed ID: 18991632
[TBL] [Abstract][Full Text] [Related]
10. Thyrotropin-releasing hormone analogs.
Colson AO; Gershengorn MC
Mini Rev Med Chem; 2006 Feb; 6(2):221-6. PubMed ID: 16472189
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biology of ring-modified l-Histidine containing thyrotropin-releasing hormone (TRH) analogues.
Meena CL; Thakur A; Nandekar PP; Sharma SS; Sangamwar AT; Jain R
Eur J Med Chem; 2016 Mar; 111():72-83. PubMed ID: 26854379
[TBL] [Abstract][Full Text] [Related]
12. Low affinity analogs of thyrotropin-releasing hormone are super-agonists.
Engel S; Neumann S; Kaur N; Monga V; Jain R; Northup J; Gershengorn MC
J Biol Chem; 2006 May; 281(19):13103-13109. PubMed ID: 16551618
[TBL] [Abstract][Full Text] [Related]
13. Combinatorial QSAR modeling of specificity and subtype selectivity of ligands binding to serotonin receptors 5HT1E and 5HT1F.
Wang XS; Tang H; Golbraikh A; Tropsha A
J Chem Inf Model; 2008 May; 48(5):997-1013. PubMed ID: 18470978
[TBL] [Abstract][Full Text] [Related]
14. A model of inverse agonist action at thyrotropin-releasing hormone receptor type 1: role of a conserved tryptophan in helix 6.
Lu X; Huang W; Worthington S; Drabik P; Osman R; Gershengorn MC
Mol Pharmacol; 2004 Nov; 66(5):1192-200. PubMed ID: 15306657
[TBL] [Abstract][Full Text] [Related]
15. Novel thyrotropin-releasing hormone analogs: a patent review.
Khomane KS; Meena CL; Jain R; Bansal AK
Expert Opin Ther Pat; 2011 Nov; 21(11):1673-91. PubMed ID: 22017410
[TBL] [Abstract][Full Text] [Related]
16. Thyrotropin-releasing hormone receptors -- similarities and differences.
Sun Y; Lu X; Gershengorn MC
J Mol Endocrinol; 2003 Apr; 30(2):87-97. PubMed ID: 12683933
[TBL] [Abstract][Full Text] [Related]
17. Agonist-induced conformational changes in thyrotropin-releasing hormone receptor type I: disulfide cross-linking and molecular modeling approaches.
Huang W; Osman R; Gershengorn MC
Biochemistry; 2005 Feb; 44(7):2419-31. PubMed ID: 15709754
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of CNS active thyrotropin-releasing hormone (TRH)-like peptides: Biological evaluation and effect on cognitive impairment induced by cerebral ischemia in mice.
Meena CL; Thakur A; Nandekar PP; Sangamwar AT; Sharma SS; Jain R
Bioorg Med Chem; 2015 Sep; 23(17):5641-53. PubMed ID: 26216015
[TBL] [Abstract][Full Text] [Related]
19. Distribution of the mRNAs encoding the thyrotropin-releasing hormone (TRH) precursor and three TRH receptors in the brain and pituitary of Xenopus laevis: effect of background color adaptation on TRH and TRH receptor gene expression.
Bidaud I; Galas L; Bulant M; Jenks BG; Ouwens DT; Jégou S; Ladram A; Roubos EW; Tonon MC; Nicolas P; Vaudry H
J Comp Neurol; 2004 Sep; 477(1):11-28. PubMed ID: 15281077
[TBL] [Abstract][Full Text] [Related]
20. Thyrotropin-releasing hormone receptor type 1 (TRH-R1), not TRH-R2, primarily mediates taltirelin actions in the CNS of mice.
Thirunarayanan N; Nir EA; Raaka BM; Gershengorn MC
Neuropsychopharmacology; 2013 May; 38(6):950-6. PubMed ID: 23303050
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]