291 related articles for article (PubMed ID: 18597482)
1. A double role for a strictly conserved serine: further insights into the dUTPase catalytic mechanism.
Palmén LG; Becker K; Bülow L; Kvassman JO
Biochemistry; 2008 Jul; 47(30):7863-74. PubMed ID: 18597482
[TBL] [Abstract][Full Text] [Related]
2. Concerted bifunctionality of the dCTP deaminase-dUTPase from Methanocaldococcus jannaschii: a structural and pre-steady state kinetic analysis.
Siggaard JH; Johansson E; Vognsen T; Helt SS; Harris P; Larsen S; Willemoës M
Arch Biochem Biophys; 2009 Oct; 490(1):42-9. PubMed ID: 19683509
[TBL] [Abstract][Full Text] [Related]
3. Structure/function analysis of a dUTPase: catalytic mechanism of a potential chemotherapeutic target.
Harris JM; McIntosh EM; Muscat GE
J Mol Biol; 1999 Apr; 288(2):275-87. PubMed ID: 10329142
[TBL] [Abstract][Full Text] [Related]
4. Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
Kovári J; Barabás O; Varga B; Békési A; Tölgyesi F; Fidy J; Nagy J; Vértessy BG
Proteins; 2008 Apr; 71(1):308-19. PubMed ID: 17932923
[TBL] [Abstract][Full Text] [Related]
5. The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue sheds light on the mechanism and suggests the "basic module" for dimeric d(C/U)TPases.
Moroz OV; Harkiolaki M; Galperin MY; Vagin AA; González-Pacanowska D; Wilson KS
J Mol Biol; 2004 Oct; 342(5):1583-97. PubMed ID: 15364583
[TBL] [Abstract][Full Text] [Related]
6. The strength of dehalogenase-substrate hydrogen bonding correlates with the rate of Meisenheimer intermediate formation.
Dong J; Lu X; Wei Y; Luo L; Dunaway-Mariano D; Carey PR
Biochemistry; 2003 Aug; 42(31):9482-90. PubMed ID: 12899635
[TBL] [Abstract][Full Text] [Related]
7. Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
Chan S; Segelke B; Lekin T; Krupka H; Cho US; Kim MY; So M; Kim CY; Naranjo CM; Rogers YC; Park MS; Waldo GS; Pashkov I; Cascio D; Perry JL; Sawaya MR
J Mol Biol; 2004 Aug; 341(2):503-17. PubMed ID: 15276840
[TBL] [Abstract][Full Text] [Related]
8. Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis.
Helt SS; Thymark M; Harris P; Aagaard C; Dietrich J; Larsen S; Willemoes M
J Mol Biol; 2008 Feb; 376(2):554-69. PubMed ID: 18164314
[TBL] [Abstract][Full Text] [Related]
9. Effect of an Asp80Ala substitution on the binding of dUTP and dUMP to Trypanosoma cruzi dUTPase.
Téllez-Sanz R; Yassin Z; Bernier-Villamor V; Ortiz-Salmerón E; Musso-Buendia JA; Barón C; Ruíz-Pérez LM; González-Pacanowska D; García-Fuentes L
Biochimie; 2007 Aug; 89(8):972-80. PubMed ID: 17459559
[TBL] [Abstract][Full Text] [Related]
10. Structural and functional consequences of substitutions at the tyrosine 55-lysine 104 hydrogen bond in Escherichia coli inorganic pyrophosphatase.
Fabrichniy IP; Kasho VN; Hyytiä T; Salminen T; Halonen P; Dudarenkov VY; Heikinheimo P; Chernyak VY; Goldman A; Lahti R; Cooperman BS; Baykov AA
Biochemistry; 1997 Jun; 36(25):7746-53. PubMed ID: 9201916
[TBL] [Abstract][Full Text] [Related]
11. Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity.
Zhang Y; Swaminathan GJ; Deshpande A; Boix E; Natesh R; Xie Z; Acharya KR; Brew K
Biochemistry; 2003 Nov; 42(46):13512-21. PubMed ID: 14621997
[TBL] [Abstract][Full Text] [Related]
12. The monomeric dUTPase from Epstein-Barr virus mimics trimeric dUTPases.
Tarbouriech N; Buisson M; Seigneurin JM; Cusack S; Burmeister WP
Structure; 2005 Sep; 13(9):1299-310. PubMed ID: 16154087
[TBL] [Abstract][Full Text] [Related]
13. Mutational, structural, and kinetic evidence for a dissociative mechanism in the GDP-mannose mannosyl hydrolase reaction.
Xia Z; Azurmendi HF; Lairson LL; Withers SG; Gabelli SB; Bianchet MA; Amzel LM; Mildvan AS
Biochemistry; 2005 Jun; 44(25):8989-97. PubMed ID: 15966723
[TBL] [Abstract][Full Text] [Related]
14. Complementary truncations of a hydrogen bond to ribose involved in transition-state stabilization by cytidine deaminase.
Carlow DC; Short SA; Wolfenden R
Biochemistry; 1998 Feb; 37(5):1199-203. PubMed ID: 9477944
[TBL] [Abstract][Full Text] [Related]
15. Investigation of a general base mechanism for ester hydrolysis in C-C hydrolase enzymes of the alpha/beta-hydrolase superfamily: a novel mechanism for the serine catalytic triad.
Li JJ; Bugg TD
Org Biomol Chem; 2007 Feb; 5(3):507-13. PubMed ID: 17252134
[TBL] [Abstract][Full Text] [Related]
16. Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius.
Mandrich L; Menchise V; Alterio V; De Simone G; Pedone C; Rossi M; Manco G
Proteins; 2008 Jun; 71(4):1721-31. PubMed ID: 18076040
[TBL] [Abstract][Full Text] [Related]
17. Crystal structure of a dUTPase.
Cedergren-Zeppezauer ES; Larsson G; Nyman PO; Dauter Z; Wilson KS
Nature; 1992 Feb; 355(6362):740-3. PubMed ID: 1311056
[TBL] [Abstract][Full Text] [Related]
18. Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis.
von Bülow R; Schmidt B; Dierks T; von Figura K; Usón I
J Mol Biol; 2001 Jan; 305(2):269-77. PubMed ID: 11124905
[TBL] [Abstract][Full Text] [Related]
19. Molecular mechanism of ADP-ribose hydrolysis by human NUDT5 from structural and kinetic studies.
Zha M; Guo Q; Zhang Y; Yu B; Ou Y; Zhong C; Ding J
J Mol Biol; 2008 Jun; 379(3):568-78. PubMed ID: 18462755
[TBL] [Abstract][Full Text] [Related]
20. Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii.
Huffman JL; Li H; White RH; Tainer JA
J Mol Biol; 2003 Aug; 331(4):885-96. PubMed ID: 12909016
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]