BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 18598945)

  • 1. Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer.
    Barbash O; Zamfirova P; Lin DI; Chen X; Yang K; Nakagawa H; Lu F; Rustgi AK; Diehl JA
    Cancer Cell; 2008 Jul; 14(1):68-78. PubMed ID: 18598945
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3ɛ.
    Barbash O; Lee EK; Diehl JA
    Oncogene; 2011 Apr; 30(17):1995-2002. PubMed ID: 21242966
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation.
    Vaites LP; Lee EK; Lian Z; Barbash O; Roy D; Wasik M; Klein-Szanto AJ; Rustgi AK; Diehl JA
    Mol Cell Biol; 2011 Nov; 31(22):4513-23. PubMed ID: 21911473
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex.
    Lin DI; Barbash O; Kumar KG; Weber JD; Harper JW; Klein-Szanto AJ; Rustgi A; Fuchs SY; Diehl JA
    Mol Cell; 2006 Nov; 24(3):355-66. PubMed ID: 17081987
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SCF(Fbx4/alphaB-crystallin) E3 ligase: when one is not enough.
    Barbash O; Diehl JA
    Cell Cycle; 2008 Oct; 7(19):2983-6. PubMed ID: 18818515
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1.
    Benzeno S; Lu F; Guo M; Barbash O; Zhang F; Herman JG; Klein PS; Rustgi A; Diehl JA
    Oncogene; 2006 Oct; 25(47):6291-303. PubMed ID: 16732330
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells.
    Wei S; Yang HC; Chuang HC; Yang J; Kulp SK; Lu PJ; Lai MD; Chen CS
    J Biol Chem; 2008 Sep; 283(39):26759-70. PubMed ID: 18650423
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FBX4 mediates rapid cyclin D1 proteolysis upon DNA damage in immortalized esophageal epithelial cells.
    Liu J; Yang H; Cheung PY; Tsao SW; Lv L; Cheung ALM
    Biochem Biophys Res Commun; 2021 May; 554():76-82. PubMed ID: 33784509
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation.
    Barbash O; Egan E; Pontano LL; Kosak J; Diehl JA
    Oncogene; 2009 Dec; 28(49):4317-25. PubMed ID: 19767775
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligase.
    Li Y; Hao B
    J Biol Chem; 2010 Apr; 285(18):13896-906. PubMed ID: 20181953
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinase-inactive glycogen synthase kinase 3beta promotes Wnt signaling and mammary tumorigenesis.
    Farago M; Dominguez I; Landesman-Bollag E; Xu X; Rosner A; Cardiff RD; Seldin DC
    Cancer Res; 2005 Jul; 65(13):5792-801. PubMed ID: 15994955
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The E3 Ubiquitin Ligase SCF(Cyclin F) Transmits AKT Signaling to the Cell-Cycle Machinery.
    Choudhury R; Bonacci T; Wang X; Truong A; Arceci A; Zhang Y; Mills CA; Kernan JL; Liu P; Emanuele MJ
    Cell Rep; 2017 Sep; 20(13):3212-3222. PubMed ID: 28954236
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alternative splicing variants of human Fbx4 disturb cyclin D1 proteolysis in human cancer.
    Chu X; Zhang T; Wang J; Li M; Zhang X; Tu J; Sun S; Chen X; Lu F
    Biochem Biophys Res Commun; 2014 Apr; 447(1):158-64. PubMed ID: 24704453
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GSK3-SCF(FBXW7) targets JunB for degradation in G2 to preserve chromatid cohesion before anaphase.
    Pérez-Benavente B; García JL; Rodríguez MS; Pineda-Lucena A; Piechaczyk M; Font de Mora J; Farràs R
    Oncogene; 2013 Apr; 32(17):2189-99. PubMed ID: 22710716
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase.
    Aggarwal P; Vaites LP; Kim JK; Mellert H; Gurung B; Nakagawa H; Herlyn M; Hua X; Rustgi AK; McMahon SB; Diehl JA
    Cancer Cell; 2010 Oct; 18(4):329-40. PubMed ID: 20951943
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels.
    Yang K; Guo Y; Stacey WC; Harwalkar J; Fretthold J; Hitomi M; Stacey DW
    BMC Cell Biol; 2006 Aug; 7():33. PubMed ID: 16942622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
    Hao B; Oehlmann S; Sowa ME; Harper JW; Pavletich NP
    Mol Cell; 2007 Apr; 26(1):131-43. PubMed ID: 17434132
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6.
    Laman H; Funes JM; Ye H; Henderson S; Galinanes-Garcia L; Hara E; Knowles P; McDonald N; Boshoff C
    EMBO J; 2005 Sep; 24(17):3104-16. PubMed ID: 16096642
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA damage-dependent cyclin D1 proteolysis: GSK3beta holds the smoking gun.
    Pontano LL; Diehl JA
    Cell Cycle; 2009 Mar; 8(6):824-7. PubMed ID: 19221502
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclin D1 over-expression correlates with beta-catenin activation, but not with H-ras mutations, and phosphorylation of Akt, GSK3 beta and ERK1/2 in mouse hepatic carcinogenesis.
    Gotoh J; Obata M; Yoshie M; Kasai S; Ogawa K
    Carcinogenesis; 2003 Mar; 24(3):435-42. PubMed ID: 12663502
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.