These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 18599816)

  • 1. Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636.
    Bhowruth V; Brown AK; Besra GS
    Microbiology (Reading); 2008 Jul; 154(Pt 7):1866-1875. PubMed ID: 18599816
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Flavonoid inhibitors as novel antimycobacterial agents targeting Rv0636, a putative dehydratase enzyme involved in Mycobacterium tuberculosis fatty acid synthase II.
    Brown AK; Papaemmanouil A; Bhowruth V; Bhatt A; Dover LG; Besra GS
    Microbiology (Reading); 2007 Oct; 153(Pt 10):3314-3322. PubMed ID: 17906131
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crucial components of Mycobacterium type II fatty acid biosynthesis (Fas-II) and their inhibitors.
    Duan X; Xiang X; Xie J
    FEMS Microbiol Lett; 2014 Nov; 360(2):87-99. PubMed ID: 25227413
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of the dehydratase component of the mycobacterial mycolic acid-synthesizing fatty acid synthase-II complex.
    Brown AK; Bhatt A; Singh A; Saparia E; Evans AF; Besra GS
    Microbiology (Reading); 2007 Dec; 153(Pt 12):4166-4173. PubMed ID: 18048930
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antimycobacterial Activity and Mechanism of Action of NAS-91.
    Gratraud P; Surolia N; Besra GS; Surolia A; Kremer L
    Antimicrob Agents Chemother; 2008 Mar; 52(3):1162-6. PubMed ID: 18086849
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms of Resistance Associated with the Inhibition of the Dehydration Step of Type II Fatty Acid Synthase in
    Grzegorzewicz AE; Gee C; Das S; Liu J; Belardinelli JM; Jones V; McNeil MR; Lee RE; Jackson M
    ACS Infect Dis; 2020 Feb; 6(2):195-204. PubMed ID: 31775512
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutations in the essential FAS II β-hydroxyacyl ACP dehydratase complex confer resistance to thiacetazone in Mycobacterium tuberculosis and Mycobacterium kansasii.
    Belardinelli JM; Morbidoni HR
    Mol Microbiol; 2012 Nov; 86(3):568-79. PubMed ID: 22994892
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis.
    Parrish NM; Kuhajda FP; Heine HS; Bishai WR; Dick JD
    J Antimicrob Chemother; 1999 Feb; 43(2):219-26. PubMed ID: 11252327
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Flavonoids as Novel Efflux Pump Inhibitors and Antimicrobials Against Both Environmental and Pathogenic Intracellular Mycobacterial Species.
    Solnier J; Martin L; Bhakta S; Bucar F
    Molecules; 2020 Feb; 25(3):. PubMed ID: 32046221
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Molecular Genetics of Mycolic Acid Biosynthesis.
    PaweŁczyk J; Kremer L
    Microbiol Spectr; 2014 Aug; 2(4):MGM2-0003-2013. PubMed ID: 26104214
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acetylene-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme.
    Senior SJ; Illarionov PA; Gurcha SS; Campbell IB; Schaeffer ML; Minnikin DE; Besra GS
    Bioorg Med Chem Lett; 2004 Jan; 14(2):373-6. PubMed ID: 14698162
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis.
    Sacco E; Covarrubias AS; O'Hare HM; Carroll P; Eynard N; Jones TA; Parish T; Daffé M; Bäckbro K; Quémard A
    Proc Natl Acad Sci U S A; 2007 Sep; 104(37):14628-33. PubMed ID: 17804795
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cloning, sequencing and characterization of a fatty acid synthase-encoding gene from Mycobacterium tuberculosis var. bovis BCG.
    Fernandes ND; Kolattukudy PE
    Gene; 1996 Apr; 170(1):95-9. PubMed ID: 8621098
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening.
    Faïon L; Djaout K; Frita R; Pintiala C; Cantrelle FX; Moune M; Vandeputte A; Bourbiaux K; Piveteau C; Herledan A; Biela A; Leroux F; Kremer L; Blaise M; Tanina A; Wintjens R; Hanoulle X; Déprez B; Willand N; Baulard AR; Flipo M
    Eur J Med Chem; 2020 Aug; 200():112440. PubMed ID: 32505086
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis.
    Guzman JD; Gupta A; Evangelopoulos D; Basavannacharya C; Pabon LC; Plazas EA; Muñoz DR; Delgado WA; Cuca LE; Ribon W; Gibbons S; Bhakta S
    J Antimicrob Chemother; 2010 Oct; 65(10):2101-7. PubMed ID: 20719764
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residue.
    Veyron-Churlet R; Molle V; Taylor RC; Brown AK; Besra GS; Zanella-Cléon I; Fütterer K; Kremer L
    J Biol Chem; 2009 Mar; 284(10):6414-24. PubMed ID: 19074144
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules.
    Zhang W; Liu LL; Lun S; Wang SS; Xiao S; Gunosewoyo H; Yang F; Tang J; Bishai WR; Yu LF
    Eur J Med Chem; 2021 Mar; 213():113202. PubMed ID: 33516983
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, antitubercular activity and mechanism of resistance of highly effective thiacetazone analogues.
    Coxon GD; Craig D; Corrales RM; Vialla E; Gannoun-Zaki L; Kremer L
    PLoS One; 2013; 8(1):e53162. PubMed ID: 23301038
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lack of Specificity of Phenotypic Screens for Inhibitors of the Mycobacterium tuberculosis FAS-II System.
    Grzegorzewicz AE; Lelièvre J; Esquivias J; Angala B; Liu J; Lee RE; McNeil MR; Jackson M
    Antimicrob Agents Chemother; 2020 Dec; 65(1):. PubMed ID: 33139282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antimycobacterial activity of UDP-galactopyranose mutase inhibitors.
    Borrelli S; Zandberg WF; Mohan S; Ko M; Martinez-Gutierrez F; Partha SK; Sanders DA; Av-Gay Y; Pinto BM
    Int J Antimicrob Agents; 2010 Oct; 36(4):364-8. PubMed ID: 20678902
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.