BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 18606182)

  • 1. Different effects of selective dopamine uptake inhibitors, GBR 12909 and WIN 35428, on HIV-1 Tat toxicity in rat fetal midbrain neurons.
    Aksenov MY; Aksenova MV; Silvers JM; Mactutus CF; Booze RM
    Neurotoxicology; 2008 Nov; 29(6):971-7. PubMed ID: 18606182
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HIV-1 Tat protein-induced rapid and reversible decrease in [3H]dopamine uptake: dissociation of [3H]dopamine uptake and [3H]2beta-carbomethoxy-3-beta-(4-fluorophenyl)tropane (WIN 35,428) binding in rat striatal synaptosomes.
    Zhu J; Mactutus CF; Wallace DR; Booze RM
    J Pharmacol Exp Ther; 2009 Jun; 329(3):1071-83. PubMed ID: 19325033
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HIV-1 Tat neurotoxicity in primary cultures of rat midbrain fetal neurons: changes in dopamine transporter binding and immunoreactivity.
    Aksenova MV; Silvers JM; Aksenov MY; Nath A; Ray PD; Mactutus CF; Booze RM
    Neurosci Lett; 2006 Mar; 395(3):235-9. PubMed ID: 16356633
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The human immunodeficiency virus-1-associated protein, Tat1-86, impairs dopamine transporters and interacts with cocaine to reduce nerve terminal function: a no-net-flux microdialysis study.
    Ferris MJ; Frederick-Duus D; Fadel J; Mactutus CF; Booze RM
    Neuroscience; 2009 Apr; 159(4):1292-9. PubMed ID: 19344635
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heteroaromatic analogs of 1-[2-(diphenylmethoxy)ethyl]- and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as high-affinity dopamine reuptake inhibitors.
    Matecka D; Lewis D; Rothman RB; Dersch CM; Wojnicki FH; Glowa JR; DeVries AC; Pert A; Rice KC
    J Med Chem; 1997 Feb; 40(5):705-16. PubMed ID: 9057857
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.
    Dutta AK; Xu C; Reith ME
    J Med Chem; 1998 Aug; 41(17):3293-7. PubMed ID: 9703474
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of novel, potent, and selective dopamine reuptake inhibitors through alteration of the piperazine ring of 1-[2-(diphenylmethoxy)ethyl]-and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909).
    Matecka D; Rothman RB; Radesca L; de Costa BR; Dersch CM; Partilla JS; Pert A; Glowa JR; Wojnicki FH; Rice KC
    J Med Chem; 1996 Nov; 39(24):4704-16. PubMed ID: 8941383
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine.
    Hsin LW; Dersch CM; Baumann MH; Stafford D; Glowa JR; Rothman RB; Jacobson AE; Rice KC
    J Med Chem; 2002 Mar; 45(6):1321-9. PubMed ID: 11882001
    [TBL] [Abstract][Full Text] [Related]  

  • 9. O-526, a piperidine analog of GBR 12909, retains high affinity for the dopamine transporter in monkey caudate-putamen.
    Madras BK; Reith ME; Meltzer PC; Dutta AK
    Eur J Pharmacol; 1994 Apr; 267(2):167-73. PubMed ID: 8050478
    [TBL] [Abstract][Full Text] [Related]  

  • 10. D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.
    Aksenov MY; Aksenova MV; Mactutus CF; Booze RM
    J Neuroimmune Pharmacol; 2012 Sep; 7(3):599-608. PubMed ID: 22552781
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oxygenated analogues of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents.
    Lewis DB; Matecka D; Zhang Y; Hsin LW; Dersch CM; Stafford D; Glowa JR; Rothman RB; Rice KC
    J Med Chem; 1999 Dec; 42(24):5029-42. PubMed ID: 10585212
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutations at tyrosine 88, lysine 92 and tyrosine 470 of human dopamine transporter result in an attenuation of HIV-1 Tat-induced inhibition of dopamine transport.
    Midde NM; Yuan Y; Quizon PM; Sun WL; Huang X; Zhan CG; Zhu J
    J Neuroimmune Pharmacol; 2015 Mar; 10(1):122-35. PubMed ID: 25604666
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and transporter binding properties of bridged piperazine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909).
    Zhang Y; Rothman RB; Dersch CM; de Costa BR; Jacobson AE; Rice KC
    J Med Chem; 2000 Dec; 43(25):4840-9. PubMed ID: 11123994
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Allosteric modulatory effects of SRI-20041 and SRI-30827 on cocaine and HIV-1 Tat protein binding to human dopamine transporter.
    Sun WL; Quizon PM; Yuan Y; Zhang W; Ananthan S; Zhan CG; Zhu J
    Sci Rep; 2017 Jun; 7(1):3694. PubMed ID: 28623359
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs.
    Desai RI; Kopajtic TA; French D; Newman AH; Katz JL
    J Pharmacol Exp Ther; 2005 Oct; 315(1):397-404. PubMed ID: 16014753
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Doses of GBR12909 that suppress cocaine self-administration in non-human primates substantially occupy dopamine transporters as measured by [11C] WIN35,428 PET scans.
    Villemagne VL; Rothman RB; Yokoi F; Rice KC; Matecka D; Dannals RF; Wong DF
    Synapse; 1999 Apr; 32(1):44-50. PubMed ID: 10188637
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HIV-1 transgenic rats display an increase in [(3)H]dopamine uptake in the prefrontal cortex and striatum.
    Zhu J; Yuan Y; Midde NM; Gomez AM; Sun WL; Quizon PM; Zhan CG
    J Neurovirol; 2016 Jun; 22(3):282-92. PubMed ID: 26501780
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cocaine-mediated enhancement of Tat toxicity in rat hippocampal cell cultures: the role of oxidative stress and D1 dopamine receptor.
    Aksenov MY; Aksenova MV; Nath A; Ray PD; Mactutus CF; Booze RM
    Neurotoxicology; 2006 Mar; 27(2):217-28. PubMed ID: 16386305
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neuronal survival and resistance to HIV-1 Tat toxicity in the primary culture of rat fetal neurons.
    Aksenova MV; Aksenov MY; Adams SM; Mactutus CF; Booze RM
    Exp Neurol; 2009 Feb; 215(2):253-63. PubMed ID: 19013459
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rat mesencephalic neuronal cells cultured for different periods as a model of dopamine transporter ontogenesis.
    Valchár M; Hanbauer I
    Mol Neurobiol; 1995; 11(1-3):111-9. PubMed ID: 8561956
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.