These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 18606684)

  • 1. Characterization of Ig gene somatic hypermutation in the absence of activation-induced cytidine deaminase.
    Longo NS; Satorius CL; Plebani A; Durandy A; Lipsky PE
    J Immunol; 2008 Jul; 181(2):1299-306. PubMed ID: 18606684
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.
    Longo NS; Lugar PL; Yavuz S; Zhang W; Krijger PH; Russ DE; Jima DD; Dave SS; Grammer AC; Lipsky PE
    Blood; 2009 Apr; 113(16):3706-15. PubMed ID: 19023113
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.
    Schrader CE; Linehan EK; Ucher AJ; Bertocci B; Stavnezer J
    DNA Repair (Amst); 2013 Dec; 12(12):1087-93. PubMed ID: 24084171
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of somatic hypermutations in the IgM switch region in human B cells.
    Horiuchi K; Imai K; Mitsui-Sekinaka K; Yeh TW; Ochs HD; Durandy A; Nonoyama S
    J Allergy Clin Immunol; 2014 Aug; 134(2):411-9. PubMed ID: 24836470
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Somatic hypermutation of VkappaJkappa rearrangements: targeting of RGYW motifs on both DNA strands and preferential selection of mutated codons within RGYW motifs.
    Foster SJ; Dörner T; Lipsky PE
    Eur J Immunol; 1999 Dec; 29(12):4011-21. PubMed ID: 10602011
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process.
    Rogozin IB; Diaz M
    J Immunol; 2004 Mar; 172(6):3382-4. PubMed ID: 15004135
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pathophysiology of B-cell intrinsic immunoglobulin class switch recombination deficiencies.
    Durandy A; Taubenheim N; Peron S; Fischer A
    Adv Immunol; 2007; 94():275-306. PubMed ID: 17560278
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ongoing somatic hypermutation of the rearranged VH but not of the V-lambda gene in EBV-transformed rheumatoid factor-producing lymphoblastoid cell line.
    Chezar I; Lobel-Lavi L; Steinitz M; Laskov R
    Mol Immunol; 2008 Nov; 46(1):80-90. PubMed ID: 18718665
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of 6912 unselected somatic hypermutations in human VDJ rearrangements reveals lack of strand specificity and correlation between phase II substitution rates and distance to the nearest 3' activation-induced cytidine deaminase target.
    Ohm-Laursen L; Barington T
    J Immunol; 2007 Apr; 178(7):4322-34. PubMed ID: 17371989
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Uracil DNA glycosylase disruption blocks Ig gene conversion and induces transition mutations.
    Saribasak H; Saribasak NN; Ipek FM; Ellwart JW; Arakawa H; Buerstedde JM
    J Immunol; 2006 Jan; 176(1):365-71. PubMed ID: 16365429
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Somatic hypermutation targeting to intrinsic hotspots of immunoglobulin genes in follicular lymphoma and multiple myeloma.
    Belessi C; Stamatopoulos K; Stavroyianni N; Zoi K; Papadaki T; Kosmas C
    Leukemia; 2001 Nov; 15(11):1772-8. PubMed ID: 11681420
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome.
    Della Mina E; Jackson KJL; Crawford AJI; Faulks ML; Pathmanandavel K; Acquarola N; O'Sullivan M; Kerre T; Naesens L; Claes K; Goodnow CC; Haerynck F; Kracker S; Meyts I; D'Orsogna LJ; Ma CS; Tangye SG
    J Clin Immunol; 2024 Feb; 44(3):66. PubMed ID: 38363477
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.
    Masuda K; Ouchida R; Takeuchi A; Saito T; Koseki H; Kawamura K; Tagawa M; Tokuhisa T; Azuma T; O-Wang J
    Proc Natl Acad Sci U S A; 2005 Sep; 102(39):13986-91. PubMed ID: 16172387
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells.
    Komori A; Xu Z; Wu X; Zan H; Casali P
    Mol Immunol; 2006 Apr; 43(11):1817-26. PubMed ID: 16412510
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Competitive repair pathways in immunoglobulin gene hypermutation.
    Reynaud CA; Delbos F; Faili A; Guéranger Q; Aoufouchi S; Weill JC
    Philos Trans R Soc Lond B Biol Sci; 2009 Mar; 364(1517):613-9. PubMed ID: 19010770
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.
    Cantaert T; Schickel JN; Bannock JM; Ng YS; Massad C; Delmotte FR; Yamakawa N; Glauzy S; Chamberlain N; Kinnunen T; Menard L; Lavoie A; Walter JE; Notarangelo LD; Bruneau J; Al-Herz W; Kilic SS; Ochs HD; Cunningham-Rundles C; van der Burg M; Kuijpers TW; Kracker S; Kaneko H; Sekinaka Y; Nonoyama S; Durandy A; Meffre E
    J Clin Invest; 2016 Nov; 126(11):4289-4302. PubMed ID: 27701145
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions.
    Li S; Zhao Y; Wang JY
    Mol Immunol; 2013 Mar; 53(3):214-7. PubMed ID: 22960197
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes.
    Mayorov VI; Rogozin IB; Adkison LR; Frahm C; Kunkel TA; Pavlov YI
    BMC Immunol; 2005 Jun; 6():10. PubMed ID: 15949042
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of strand biased 'G'.C hypermutation in human immunoglobulin V(lambda) gene segments suggests that both DNA strands are targets for deamination by activation-induced cytidine deaminase.
    Boursier L; Su W; Spencer J
    Mol Immunol; 2004 Mar; 40(17):1273-8. PubMed ID: 15128044
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation-induced cytidine deaminase-mediated hypermutation in the DT40 cell line.
    Arakawa H; Buerstedde JM
    Philos Trans R Soc Lond B Biol Sci; 2009 Mar; 364(1517):639-44. PubMed ID: 19008193
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.