153 related articles for article (PubMed ID: 18608754)
1. Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Campylobacter jejuni.
Musso-Buendía JA; Vidal AE; Kasinthan G; Nguyen C; Carrero-Lérida J; Ruiz-Pérez LM; Wilson K; Johansson NG; Gilbert IH; González-Pacanowska D
J Enzyme Inhib Med Chem; 2009 Feb; 24(1):111-6. PubMed ID: 18608754
[TBL] [Abstract][Full Text] [Related]
2. Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Leishmania major.
Hidalgo-Zarco F; Camacho AG; Bernier-Villamor V; Nord J; Ruiz-Pérez LM; González-Pacanowska D
Protein Sci; 2001 Jul; 10(7):1426-33. PubMed ID: 11420444
[TBL] [Abstract][Full Text] [Related]
3. The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue sheds light on the mechanism and suggests the "basic module" for dimeric d(C/U)TPases.
Moroz OV; Harkiolaki M; Galperin MY; Vagin AA; González-Pacanowska D; Wilson KS
J Mol Biol; 2004 Oct; 342(5):1583-97. PubMed ID: 15364583
[TBL] [Abstract][Full Text] [Related]
4. The crystal structure of the Leishmania major deoxyuridine triphosphate nucleotidohydrolase in complex with nucleotide analogues, dUMP, and deoxyuridine.
Hemsworth GR; Moroz OV; Fogg MJ; Scott B; Bosch-Navarrete C; González-Pacanowska D; Wilson KS
J Biol Chem; 2011 May; 286(18):16470-81. PubMed ID: 21454646
[TBL] [Abstract][Full Text] [Related]
5. Kinetic and thermodynamic characterization of dUTP hydrolysis by Plasmodium falciparum dUTPase.
Quesada-Soriano I; Leal I; Casas-Solvas JM; Vargas-Berenguel A; Barón C; Ruiz-Pérez LM; González-Pacanowska D; García-Fuentes L
Biochim Biophys Acta; 2008 Sep; 1784(9):1347-55. PubMed ID: 18586121
[TBL] [Abstract][Full Text] [Related]
6. Depletion of dimeric all-alpha dUTPase induces DNA strand breaks and impairs cell cycle progression in Trypanosoma brucei.
Castillo-Acosta VM; Estévez AM; Vidal AE; Ruiz-Perez LM; González-Pacanowska D
Int J Biochem Cell Biol; 2008; 40(12):2901-13. PubMed ID: 18656547
[TBL] [Abstract][Full Text] [Related]
7. Structure/function analysis of a dUTPase: catalytic mechanism of a potential chemotherapeutic target.
Harris JM; McIntosh EM; Muscat GE
J Mol Biol; 1999 Apr; 288(2):275-87. PubMed ID: 10329142
[TBL] [Abstract][Full Text] [Related]
8. Properties of Leishmania major dUTP nucleotidohydrolase, a distinct nucleotide-hydrolysing enzyme in kinetoplastids.
Camacho A; Hidalgo-Zarco F; Bernier-Villamor V; Ruiz-Pérez LM; González-Pacanowska D
Biochem J; 2000 Feb; 346 Pt 1(Pt 1):163-8. PubMed ID: 10657253
[TBL] [Abstract][Full Text] [Related]
9. Kinetic properties and specificity of trimeric Plasmodium falciparum and human dUTPases.
Quesada-Soriano I; Casas-Solvas JM; Recio E; Ruiz-Pérez LM; Vargas-Berenguel A; González-Pacanowska D; García-Fuentes L
Biochimie; 2010 Feb; 92(2):178-86. PubMed ID: 19879316
[TBL] [Abstract][Full Text] [Related]
10. Synthesis of 2'-deoxyuridine 5'-(alpha,beta-imido) triphosphate: a substrate analogue and potent inhibitor of dUTPase.
Persson T; Larsson G; Nyman PO
Bioorg Med Chem; 1996 Apr; 4(4):553-6. PubMed ID: 8735843
[TBL] [Abstract][Full Text] [Related]
11. dUTPase from the retrovirus equine infectious anemia virus: specificity, turnover and inhibition.
Nord J; Larsson G; Kvassman JO; Rosengren AM; Nyman PO
FEBS Lett; 1997 Sep; 414(2):271-4. PubMed ID: 9315700
[TBL] [Abstract][Full Text] [Related]
12. Kinetic characterization of dUTPase from Escherichia coli.
Larsson G; Nyman PO; Kvassman JO
J Biol Chem; 1996 Sep; 271(39):24010-6. PubMed ID: 8798636
[TBL] [Abstract][Full Text] [Related]
13. Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
Kovári J; Barabás O; Varga B; Békési A; Tölgyesi F; Fidy J; Nagy J; Vértessy BG
Proteins; 2008 Apr; 71(1):308-19. PubMed ID: 17932923
[TBL] [Abstract][Full Text] [Related]
14. Kinetic properties and stereospecificity of the monomeric dUTPase from herpes simplex virus type 1.
Bergman AC; Nyman PO; Larsson G
FEBS Lett; 1998 Dec; 441(2):327-30. PubMed ID: 9883909
[TBL] [Abstract][Full Text] [Related]
15. A double role for a strictly conserved serine: further insights into the dUTPase catalytic mechanism.
Palmén LG; Becker K; Bülow L; Kvassman JO
Biochemistry; 2008 Jul; 47(30):7863-74. PubMed ID: 18597482
[TBL] [Abstract][Full Text] [Related]
16. Deinococcus radiodurans DR2231 is a two-metal-ion mechanism hydrolase with exclusive activity on dUTP.
Mota CS; Gonçalves AM; de Sanctis D
FEBS J; 2016 Dec; 283(23):4274-4290. PubMed ID: 27739259
[TBL] [Abstract][Full Text] [Related]
17. Characterization of deoxyuridine 5'-triphosphate nucleotidohydrolase from Trypanosoma cruzi.
Bernier-Villamor V; Camacho A; Hidalgo-Zarco F; Pérez J; Ruiz-Pérez LM; González-Pacanowska D
FEBS Lett; 2002 Aug; 526(1-3):147-50. PubMed ID: 12208522
[TBL] [Abstract][Full Text] [Related]
18. Trypanosomal dUTPases as potential targets for drug design.
Hidalgo-Zarco F; González-Pazanowska D
Curr Protein Pept Sci; 2001 Dec; 2(4):389-97. PubMed ID: 12374098
[TBL] [Abstract][Full Text] [Related]
19. Pyrimidine requirements in deoxyuridine triphosphate nucleotidohydrolase deficient Trypanosoma brucei mutants.
Castillo-Acosta VM; Aguilar-Pereyra F; García-Caballero D; Vidal AE; Ruiz-Pérez LM; González-Pacanowska D
Mol Biochem Parasitol; 2013 Jan; 187(1):9-13. PubMed ID: 23201394
[TBL] [Abstract][Full Text] [Related]
20. Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits.
Mol CD; Harris JM; McIntosh EM; Tainer JA
Structure; 1996 Sep; 4(9):1077-92. PubMed ID: 8805593
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]