409 related articles for article (PubMed ID: 18621733)
1. Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain.
Manna D; Bhardwaj N; Vora MS; Stahelin RV; Lu H; Cho W
J Biol Chem; 2008 Sep; 283(38):26047-58. PubMed ID: 18621733
[TBL] [Abstract][Full Text] [Related]
2. The C2 domains of classical PKCs are specific PtdIns(4,5)P2-sensing domains with different affinities for membrane binding.
Guerrero-Valero M; Marín-Vicente C; Gómez-Fernández JC; Corbalán-García S
J Mol Biol; 2007 Aug; 371(3):608-21. PubMed ID: 17586528
[TBL] [Abstract][Full Text] [Related]
3. The C2 domain of PKCalpha is a Ca2+ -dependent PtdIns(4,5)P2 sensing domain: a new insight into an old pathway.
Sánchez-Bautista S; Marín-Vicente C; Gómez-Fernández JC; Corbalán-García S
J Mol Biol; 2006 Oct; 362(5):901-14. PubMed ID: 16949603
[TBL] [Abstract][Full Text] [Related]
4. Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.
Corbin JA; Evans JH; Landgraf KE; Falke JJ
Biochemistry; 2007 Apr; 46(14):4322-36. PubMed ID: 17367165
[TBL] [Abstract][Full Text] [Related]
5. Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.
Guerrero-Valero M; Ferrer-Orta C; Querol-Audí J; Marin-Vicente C; Fita I; Gómez-Fernández JC; Verdaguer N; Corbalán-García S
Proc Natl Acad Sci U S A; 2009 Apr; 106(16):6603-7. PubMed ID: 19346474
[TBL] [Abstract][Full Text] [Related]
6. Membrane docking geometry and target lipid stoichiometry of membrane-bound PKCα C2 domain: a combined molecular dynamics and experimental study.
Lai CL; Landgraf KE; Voth GA; Falke JJ
J Mol Biol; 2010 Sep; 402(2):301-10. PubMed ID: 20659476
[TBL] [Abstract][Full Text] [Related]
7. Mechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domains.
Manna D; Albanese A; Park WS; Cho W
J Biol Chem; 2007 Nov; 282(44):32093-105. PubMed ID: 17823121
[TBL] [Abstract][Full Text] [Related]
8. The PtdIns(4,5)P2 ligand itself influences the localization of PKCalpha in the plasma membrane of intact living cells.
Marín-Vicente C; Nicolás FE; Gómez-Fernández JC; Corbalán-García S
J Mol Biol; 2008 Apr; 377(4):1038-52. PubMed ID: 18304574
[TBL] [Abstract][Full Text] [Related]
9. The origin of C1A-C2 interdomain interactions in protein kinase Calpha.
Stahelin RV; Wang J; Blatner NR; Rafter JD; Murray D; Cho W
J Biol Chem; 2005 Oct; 280(43):36452-63. PubMed ID: 16079140
[TBL] [Abstract][Full Text] [Related]
10. Role of the lysine-rich cluster of the C2 domain in the phosphatidylserine-dependent activation of PKCalpha.
Rodríguez-Alfaro JA; Gomez-Fernandez JC; Corbalan-Garcia S
J Mol Biol; 2004 Jan; 335(4):1117-29. PubMed ID: 14698304
[TBL] [Abstract][Full Text] [Related]
11. Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study.
Landgraf KE; Malmberg NJ; Falke JJ
Biochemistry; 2008 Aug; 47(32):8301-16. PubMed ID: 18610985
[TBL] [Abstract][Full Text] [Related]
12. Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain.
Evans JH; Murray D; Leslie CC; Falke JJ
Mol Biol Cell; 2006 Jan; 17(1):56-66. PubMed ID: 16236797
[TBL] [Abstract][Full Text] [Related]
13. The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane.
Ivetac I; Munday AD; Kisseleva MV; Zhang XM; Luff S; Tiganis T; Whisstock JC; Rowe T; Majerus PW; Mitchell CA
Mol Biol Cell; 2005 May; 16(5):2218-33. PubMed ID: 15716355
[TBL] [Abstract][Full Text] [Related]
14. A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains.
Rameh LE; Arvidsson Ak; Carraway KL; Couvillon AD; Rathbun G; Crompton A; VanRenterghem B; Czech MP; Ravichandran KS; Burakoff SJ; Wang DS; Chen CS; Cantley LC
J Biol Chem; 1997 Aug; 272(35):22059-66. PubMed ID: 9268346
[TBL] [Abstract][Full Text] [Related]
15. Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-α.
Ziemba BP; Li J; Landgraf KE; Knight JD; Voth GA; Falke JJ
Biochemistry; 2014 Mar; 53(10):1697-713. PubMed ID: 24559055
[TBL] [Abstract][Full Text] [Related]
16. ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P
Ghai R; Du X; Wang H; Dong J; Ferguson C; Brown AJ; Parton RG; Wu JW; Yang H
Nat Commun; 2017 Oct; 8(1):757. PubMed ID: 28970484
[TBL] [Abstract][Full Text] [Related]
17. The ATP-dependent membrane localization of protein kinase Calpha is regulated by Ca2+ influx and phosphatidylinositol 4,5-bisphosphate in differentiated PC12 cells.
Marín-Vicente C; Gómez-Fernández JC; Corbalán-García S
Mol Biol Cell; 2005 Jun; 16(6):2848-61. PubMed ID: 15814842
[TBL] [Abstract][Full Text] [Related]
18. Membrane activity of the phospholipase C-delta1 pleckstrin homology (PH) domain.
Flesch FM; Yu JW; Lemmon MA; Burger KN
Biochem J; 2005 Jul; 389(Pt 2):435-41. PubMed ID: 15755258
[TBL] [Abstract][Full Text] [Related]
19. PI(4,5)P
Sohn M; Korzeniowski M; Zewe JP; Wills RC; Hammond GRV; Humpolickova J; Vrzal L; Chalupska D; Veverka V; Fairn GD; Boura E; Balla T
J Cell Biol; 2018 May; 217(5):1797-1813. PubMed ID: 29472386
[TBL] [Abstract][Full Text] [Related]
20. The C2 domains of Rabphilin3A specifically bind phosphatidylinositol 4,5-bisphosphate containing vesicles in a Ca2+-dependent manner. In vitro characteristics and possible significance.
Chung SH; Song WJ; Kim K; Bednarski JJ; Chen J; Prestwich GD; Holz RW
J Biol Chem; 1998 Apr; 273(17):10240-8. PubMed ID: 9553075
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]