BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

103 related articles for article (PubMed ID: 18623169)

  • 1. Subtype selective kainic acid receptor agonists: discovery and approaches to rational design.
    Bunch L; Krogsgaard-Larsen P
    Med Res Rev; 2009 Jan; 29(1):3-28. PubMed ID: 18623169
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stereostructure-activity studies on agonists at the AMPA and kainate subtypes of ionotropic glutamate receptors.
    Johansen TN; Greenwood JR; Frydenvang K; Madsen U; Krogsgaard-Larsen P
    Chirality; 2003 Feb; 15(2):167-79. PubMed ID: 12520509
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine.
    Frydenvang K; Lash LL; Naur P; Postila PA; Pickering DS; Smith CM; Gajhede M; Sasaki M; Sakai R; Pentikaïnen OT; Swanson GT; Kastrup JS
    J Biol Chem; 2009 May; 284(21):14219-29. PubMed ID: 19297335
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Divergent pharmacological activity of novel marine-derived excitatory amino acids on glutamate receptors.
    Sanders JM; Ito K; Settimo L; Pentikäinen OT; Shoji M; Sasaki M; Johnson MS; Sakai R; Swanson GT
    J Pharmacol Exp Ther; 2005 Sep; 314(3):1068-78. PubMed ID: 15914675
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, total synthesis, and biological evaluation of neodysiherbaine A derivative as potential probes.
    Sasaki M; Tsubone K; Shoji M; Oikawa M; Shimamoto K; Sakai R
    Bioorg Med Chem Lett; 2006 Nov; 16(22):5784-7. PubMed ID: 16949819
    [TBL] [Abstract][Full Text] [Related]  

  • 6. (S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology.
    Brehm L; Greenwood JR; Hansen KB; Nielsen B; Egebjerg J; Stensbøl TB; Bräuner-Osborne H; Sløk FA; Kronborg TT; Krogsgaard-Larsen P
    J Med Chem; 2003 Apr; 46(8):1350-8. PubMed ID: 12672235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kainate receptor agonists and antagonists mediate tolerance to kainic acid and reduce high-affinity GTPase activity in young, but not aged, rat hippocampus.
    Hesp BR; Wrightson T; Mullaney I; Kerr DS
    J Neurochem; 2004 Jul; 90(1):70-9. PubMed ID: 15198668
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ligands for ionotropic glutamate receptors.
    Swanson GT; Sakai R
    Prog Mol Subcell Biol; 2009; 46():123-57. PubMed ID: 19184587
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7.
    Sagot E; Pickering DS; Pu X; Umberti M; Stensbøl TB; Nielsen B; Chapelet M; Bolte J; Gefflaut T; Bunch L
    J Med Chem; 2008 Jul; 51(14):4093-103. PubMed ID: 18578478
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacological characterization of (4R)-alkyl glutamate analogues at the ionotropic glutamate receptors--focus on subtypes iGlu(5-7).
    Bunch L; Gefflaut T; Alaux S; Sagot E; Nielsen B; Pickering DS
    Eur J Pharmacol; 2009 May; 609(1-3):1-4. PubMed ID: 19285062
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploring kainate receptor pharmacology using molecular dynamics simulations.
    Postila PA; Swanson GT; Pentikäinen OT
    Neuropharmacology; 2010 Feb; 58(2):515-27. PubMed ID: 19737573
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
    Hald H; Naur P; Pickering DS; Sprogøe D; Madsen U; Timmermann DB; Ahring PK; Liljefors T; Schousboe A; Egebjerg J; Gajhede M; Kastrup JS
    J Biol Chem; 2007 Aug; 282(35):25726-36. PubMed ID: 17581823
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine.
    Lash-Van Wyhe LL; Postila PA; Tsubone K; Sasaki M; Pentikäinen OT; Sakai R; Swanson GT
    Neuropharmacology; 2010 Mar; 58(3):640-9. PubMed ID: 19962997
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (-)-dysiherbaine.
    Cohen JL; Limon A; Miledi R; Chamberlin AR
    Bioorg Med Chem Lett; 2006 Apr; 16(8):2189-94. PubMed ID: 16455241
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Electrophysiological effects of kainic acid on vasopressin-enhanced green fluorescent protein and oxytocin-monomeric red fluorescent protein 1 neurones isolated from the supraoptic nucleus in transgenic rats.
    Ohkubo J; Ohbuchi T; Yoshimura M; Maruyama T; Ishikura T; Matsuura T; Suzuki H; Ueta Y
    J Neuroendocrinol; 2014 Jan; 26(1):43-51. PubMed ID: 24341559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Determination of binding site residues responsible for the subunit selectivity of novel marine-derived compounds on kainate receptors.
    Sanders JM; Pentikäinen OT; Settimo L; Pentikäinen U; Shoji M; Sasaki M; Sakai R; Johnson MS; Swanson GT
    Mol Pharmacol; 2006 Jun; 69(6):1849-60. PubMed ID: 16537793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Total synthesis and biological evaluation of neodysiherbaine A and analogues.
    Shoji M; Akiyama N; Tsubone K; Lash LL; Sanders JM; Swanson GT; Sakai R; Shimamoto K; Oikawa M; Sasaki M
    J Org Chem; 2006 Jul; 71(14):5208-20. PubMed ID: 16808508
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization.
    Clausen RP; Naur P; Kristensen AS; Greenwood JR; Strange M; Bräuner-Osborne H; Jensen AA; Nielsen AS; Geneser U; Ringgaard LM; Nielsen B; Pickering DS; Brehm L; Gajhede M; Krogsgaard-Larsen P; Kastrup JS
    J Med Chem; 2009 Aug; 52(15):4911-22. PubMed ID: 19588945
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rational design and enantioselective synthesis of (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid - a novel inhibitor at human glutamate transporter subtypes 1, 2, and 3.
    Bunch L; Nielsen B; Jensen AA; Bräuner-Osborne H
    J Med Chem; 2006 Jan; 49(1):172-8. PubMed ID: 16392801
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enantioselective Synthesis of (-)-Dysiherbaine.
    Do H; Kang CW; Cho JH; Gilbertson SR
    Org Lett; 2015 Aug; 17(16):3972-4. PubMed ID: 26258884
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.