These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 18631251)

  • 1. Transgenic overexpression of insulin receptor substrate 1 in hepatocytes enhances hepatocellular proliferation in young mice only.
    Mohr L; Banerjee K; Kleinschmidt M; Bartolomé Rodríguez MM; Wands JR
    Hepatol Res; 2008 Dec; 38(12):1233-40. PubMed ID: 18631251
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ethanol inhibits hepatocyte proliferation in insulin receptor substrate 1 transgenic mice.
    Mohr L; Tanaka S; Wands JR
    Gastroenterology; 1998 Dec; 115(6):1558-65. PubMed ID: 9834285
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liver.
    Longato L; de la Monte S; Kuzushita N; Horimoto M; Rogers AB; Slagle BL; Wands JR
    Hepatology; 2009 Jun; 49(6):1935-43. PubMed ID: 19475691
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling.
    Cousin SP; Hügl SR; Myers MG; White MF; Reifel-Miller A; Rhodes CJ
    Biochem J; 1999 Dec; 344 Pt 3(Pt 3):649-58. PubMed ID: 10585851
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insulin receptor substrate 1 overexpression in human hepatocellular carcinoma cells prevents transforming growth factor beta1-induced apoptosis.
    Tanaka S; Wands JR
    Cancer Res; 1996 Aug; 56(15):3391-4. PubMed ID: 8758899
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules.
    Tanaka S; Ito T; Wands JR
    J Biol Chem; 1996 Jun; 271(24):14610-6. PubMed ID: 8662827
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of human insulin receptor substrate 1 induces cellular transformation with activation of mitogen-activated protein kinases.
    Ito T; Sasaki Y; Wands JR
    Mol Cell Biol; 1996 Mar; 16(3):943-51. PubMed ID: 8622697
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
    Welsh N; Makeeva N; Welsh M
    Mol Med; 2002 Nov; 8(11):695-704. PubMed ID: 12520086
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutive over-expression of the insulin receptor substrate-1 causes functional up-regulation of Fas receptor.
    Wiedmann M; Tamaki S; Silberman R; de la Monte SM; Cousens L; Wands JR
    J Hepatol; 2003 Jun; 38(6):803-10. PubMed ID: 12763374
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin receptor substrate-4 signaling in quiescent rat hepatocytes and in regenerating rat liver.
    Escribano O; Fernández-Moreno MD; Zueco JA; Menor C; Fueyo J; Ropero RM; Diaz-Laviada I; Román ID; Guijarro LG
    Hepatology; 2003 Jun; 37(6):1461-9. PubMed ID: 12774026
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Multiple signaling pathways mediate interleukin-4-induced 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene expression in human breast cancer cells.
    Gingras S; Côté S; Simard J
    Mol Endocrinol; 2000 Feb; 14(2):229-40. PubMed ID: 10674396
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Upregulation of the insulin receptor and type I insulin-like growth factor receptor are early events in hepatocarcinogenesis.
    Aleem E; Nehrbass D; Klimek F; Mayer D; Bannasch P
    Toxicol Pathol; 2011 Apr; 39(3):524-43. PubMed ID: 21411721
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
    Annerén C; Welsh M
    Mol Med; 2002 Nov; 8(11):705-13. PubMed ID: 12520087
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cells.
    Radhakrishnan Y; Busby WH; Shen X; Maile LA; Clemmons DR
    J Biol Chem; 2010 May; 285(21):15682-95. PubMed ID: 20207740
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeted hepatic overexpression of human IRS-1: postnatal effects in the developing mouse.
    Giannone PJ; Abu Dayyeh BK; Bienieki TC; Wands JR; Gruppuso PA
    Biochim Biophys Acta; 2004 May; 1672(2):112-9. PubMed ID: 15110093
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations.
    Gahr S; Merger M; Bollheimer LC; Hammerschmied CG; Schölmerich J; Hügl SR
    J Mol Endocrinol; 2002 Apr; 28(2):99-110. PubMed ID: 11932207
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
    Lingohr MK; Dickson LM; McCuaig JF; Hugl SR; Twardzik DR; Rhodes CJ
    Diabetes; 2002 Apr; 51(4):966-76. PubMed ID: 11916914
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insulin receptor substrate-1 is the predominant signaling molecule activated by insulin-like growth factor-I, insulin, and interleukin-4 in estrogen receptor-positive human breast cancer cells.
    Jackson JG; White MF; Yee D
    J Biol Chem; 1998 Apr; 273(16):9994-10003. PubMed ID: 9545345
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Growth factor-specific regulation of insulin receptor substrate-1 expression in MCF-7 breast carcinoma cells: effects on the insulin-like growth factor signaling pathway.
    Lassarre C; Ricort JM
    Endocrinology; 2003 Nov; 144(11):4811-9. PubMed ID: 12960057
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin signaling through insulin receptor substrate 1 and 2 in normal liver development.
    Khamzina L; Gruppuso PA; Wands JR
    Gastroenterology; 2003 Aug; 125(2):572-85. PubMed ID: 12891559
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.