339 related articles for article (PubMed ID: 18632984)
1. Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex.
Guirouilh-Barbat J; Redon C; Pommier Y
Mol Biol Cell; 2008 Sep; 19(9):3969-81. PubMed ID: 18632984
[TBL] [Abstract][Full Text] [Related]
2. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
Ewald B; Sampath D; Plunkett W
Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
[TBL] [Abstract][Full Text] [Related]
3. Zalypsis (PM00104) is a potent inducer of gamma-H2AX foci and reveals the importance of the C ring of trabectedin for transcription-coupled repair inhibition.
Guirouilh-Barbat J; Antony S; Pommier Y
Mol Cancer Ther; 2009 Jul; 8(7):2007-14. PubMed ID: 19584237
[TBL] [Abstract][Full Text] [Related]
4. Induction of glutathione-dependent DNA double-strand breaks by the novel anticancer drug brostallicin.
Guirouilh-Barbat J; Zhang YW; Pommier Y
Mol Cancer Ther; 2009 Jul; 8(7):1985-94. PubMed ID: 19584235
[TBL] [Abstract][Full Text] [Related]
5. Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus.
Hollingworth R; Horniblow RD; Forrest C; Stewart GS; Grand RJ
J Virol; 2017 Nov; 91(22):. PubMed ID: 28855246
[TBL] [Abstract][Full Text] [Related]
6. Von Hippel-Lindau-coupled and transcription-coupled nucleotide excision repair-dependent degradation of RNA polymerase II in response to trabectedin.
Aune GJ; Takagi K; Sordet O; Guirouilh-Barbat J; Antony S; Bohr VA; Pommier Y
Clin Cancer Res; 2008 Oct; 14(20):6449-55. PubMed ID: 18927284
[TBL] [Abstract][Full Text] [Related]
7. The Mre11/Rad50/Nbs1 complex interacts with the mismatch repair system and contributes to temozolomide-induced G2 arrest and cytotoxicity.
Mirzoeva OK; Kawaguchi T; Pieper RO
Mol Cancer Ther; 2006 Nov; 5(11):2757-66. PubMed ID: 17121922
[TBL] [Abstract][Full Text] [Related]
8. Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.
Wang Q; Goldstein M; Alexander P; Wakeman TP; Sun T; Feng J; Lou Z; Kastan MB; Wang XF
EMBO J; 2014 Apr; 33(8):862-77. PubMed ID: 24534091
[TBL] [Abstract][Full Text] [Related]
9. Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair.
Park S; Kang JM; Kim SJ; Kim H; Hong S; Lee YJ; Kim SJ
Cell Mol Life Sci; 2015 Feb; 72(3):583-596. PubMed ID: 25063542
[TBL] [Abstract][Full Text] [Related]
10. MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.
Yuan J; Chen J
J Biol Chem; 2010 Jan; 285(2):1097-104. PubMed ID: 19910469
[TBL] [Abstract][Full Text] [Related]
11. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
[TBL] [Abstract][Full Text] [Related]
12. Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
He J; Shi LZ; Truong LN; Lu CS; Razavian N; Li Y; Negrete A; Shiloach J; Berns MW; Wu X
J Biol Chem; 2012 Sep; 287(38):31747-56. PubMed ID: 22833675
[TBL] [Abstract][Full Text] [Related]
13. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
[TBL] [Abstract][Full Text] [Related]
14. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.
Cerosaletti K; Concannon P
J Biol Chem; 2004 Sep; 279(37):38813-9. PubMed ID: 15234984
[TBL] [Abstract][Full Text] [Related]
15. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
Williams RS; Williams JS; Tainer JA
Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
[TBL] [Abstract][Full Text] [Related]
16. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks.
Helmink BA; Bredemeyer AL; Lee BS; Huang CY; Sharma GG; Walker LM; Bednarski JJ; Lee WL; Pandita TK; Bassing CH; Sleckman BP
J Exp Med; 2009 Mar; 206(3):669-79. PubMed ID: 19221393
[TBL] [Abstract][Full Text] [Related]
17. Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.
Jazayeri A; Balestrini A; Garner E; Haber JE; Costanzo V
EMBO J; 2008 Jul; 27(14):1953-62. PubMed ID: 18596698
[TBL] [Abstract][Full Text] [Related]
18. Deubiquitinase USP2 stabilizes the MRE11-RAD50-NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1.
Kim H; Kim D; Choi H; Shin G; Lee JK
J Biol Chem; 2023 Jan; 299(1):102752. PubMed ID: 36436562
[TBL] [Abstract][Full Text] [Related]
19. The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM.
Paull TT; Lee JH
Cell Cycle; 2005 Jun; 4(6):737-40. PubMed ID: 15908798
[TBL] [Abstract][Full Text] [Related]
20. NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein.
Zhou H; Kawamura K; Yanagihara H; Kobayashi J; Zhang-Akiyama QM
J Radiat Res; 2017 Jul; 58(4):487-494. PubMed ID: 28369484
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]