145 related articles for article (PubMed ID: 18635748)
1. Phenylalanine 169 in the second extracellular loop of the human histamine H4 receptor is responsible for the difference in agonist binding between human and mouse H4 receptors.
Lim HD; Jongejan A; Bakker RA; Haaksma E; de Esch IJ; Leurs R
J Pharmacol Exp Ther; 2008 Oct; 327(1):88-96. PubMed ID: 18635748
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological characterization of the new histamine H4 receptor agonist VUF 8430.
Lim HD; Adami M; Guaita E; Werfel T; Smits RA; de Esch IJ; Bakker RA; Gutzmer R; Coruzzi G; Leurs R
Br J Pharmacol; 2009 May; 157(1):34-43. PubMed ID: 19413569
[TBL] [Abstract][Full Text] [Related]
3. Delineation of agonist binding to the human histamine H4 receptor using mutational analysis, homology modeling, and ab initio calculations.
Jongejan A; Lim HD; Smits RA; de Esch IJ; Haaksma E; Leurs R
J Chem Inf Model; 2008 Jul; 48(7):1455-63. PubMed ID: 18553960
[TBL] [Abstract][Full Text] [Related]
4. Molecular modeling and site-specific mutagenesis of the histamine-binding site of the histamine H4 receptor.
Shin N; Coates E; Murgolo NJ; Morse KL; Bayne M; Strader CD; Monsma FJ
Mol Pharmacol; 2002 Jul; 62(1):38-47. PubMed ID: 12065753
[TBL] [Abstract][Full Text] [Related]
5. Role of the second and third extracellular loops of the histamine H(4) receptor in receptor activation.
Brunskole I; Strasser A; Seifert R; Buschauer A
Naunyn Schmiedebergs Arch Pharmacol; 2011 Sep; 384(3):301-17. PubMed ID: 21800093
[TBL] [Abstract][Full Text] [Related]
6. Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
Lim HD; van Rijn RM; Ling P; Bakker RA; Thurmond RL; Leurs R
J Pharmacol Exp Ther; 2005 Sep; 314(3):1310-21. PubMed ID: 15947036
[TBL] [Abstract][Full Text] [Related]
7. Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist.
Lim HD; Smits RA; Bakker RA; van Dam CM; de Esch IJ; Leurs R
J Med Chem; 2006 Nov; 49(23):6650-1. PubMed ID: 17154494
[TBL] [Abstract][Full Text] [Related]
8. Agonist-biased signaling at the histamine H4 receptor: JNJ7777120 recruits β-arrestin without activating G proteins.
Rosethorne EM; Charlton SJ
Mol Pharmacol; 2011 Apr; 79(4):749-57. PubMed ID: 21134907
[TBL] [Abstract][Full Text] [Related]
9. Paradoxical stimulatory effects of the "standard" histamine H4-receptor antagonist JNJ7777120: the H4 receptor joins the club of 7 transmembrane domain receptors exhibiting functional selectivity.
Seifert R; Schneider EH; Dove S; Brunskole I; Neumann D; Strasser A; Buschauer A
Mol Pharmacol; 2011 Apr; 79(4):631-8. PubMed ID: 21266488
[TBL] [Abstract][Full Text] [Related]
10. Binding mode analysis and enrichment studies on homology models of the human histamine H4 receptor.
Kiss R; Noszál B; Rácz A; Falus A; Eros D; Keseru GM
Eur J Med Chem; 2008 May; 43(5):1059-70. PubMed ID: 17900762
[TBL] [Abstract][Full Text] [Related]
11. Molecular cloning of monkey histamine H4 receptor.
Oda T; Matsumoto S; Matsumoto M; Takasaki J; Kamohara M; Soga T; Hiyama H; Kobori M; Katoh M
J Pharmacol Sci; 2005 Jul; 98(3):319-22. PubMed ID: 15968139
[TBL] [Abstract][Full Text] [Related]
12. Molecular determinants of ligand binding to H4R species variants.
Lim HD; de Graaf C; Jiang W; Sadek P; McGovern PM; Istyastono EP; Bakker RA; de Esch IJ; Thurmond RL; Leurs R
Mol Pharmacol; 2010 May; 77(5):734-43. PubMed ID: 20103609
[TBL] [Abstract][Full Text] [Related]
13. Molecular determinants of selective agonist and antagonist binding to the histamine H₄ receptor.
Istyastono EP; de Graaf C; de Esch IJ; Leurs R
Curr Top Med Chem; 2011; 11(6):661-79. PubMed ID: 21261593
[TBL] [Abstract][Full Text] [Related]
14. Expression and functional properties of canine, rat, and murine histamine H₄ receptors in Sf9 insect cells.
Schnell D; Brunskole I; Ladova K; Schneider EH; Igel P; Dove S; Buschauer A; Seifert R
Naunyn Schmiedebergs Arch Pharmacol; 2011 May; 383(5):457-70. PubMed ID: 21359967
[TBL] [Abstract][Full Text] [Related]
15. Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.
Liu C; Wilson SJ; Kuei C; Lovenberg TW
J Pharmacol Exp Ther; 2001 Oct; 299(1):121-30. PubMed ID: 11561071
[TBL] [Abstract][Full Text] [Related]
16. Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 98(3.36) of the human histamine H₄ receptor.
Nijmeijer S; Engelhardt H; Schultes S; van de Stolpe AC; Lusink V; de Graaf C; Wijtmans M; Haaksma EE; de Esch IJ; Stachurski K; Vischer HF; Leurs R
Br J Pharmacol; 2013 Sep; 170(1):89-100. PubMed ID: 23347159
[TBL] [Abstract][Full Text] [Related]
17. Effects of histamine H4 receptor ligands in a mouse model of gastric ulceration.
Adami M; Pozzoli C; Menozzi A; Bertini S; Passeri B; Cantoni AM; Smits R; de Esch I; Leurs R; Coruzzi G
Pharmacology; 2012; 89(5-6):287-94. PubMed ID: 22538763
[TBL] [Abstract][Full Text] [Related]
18. Activation mechanism of the human histamine H4 receptor--an explicit membrane molecular dynamics simulation study.
Jójárt B; Kiss R; Viskolcz B; Keseru GM
J Chem Inf Model; 2008 Jun; 48(6):1199-210. PubMed ID: 18572901
[TBL] [Abstract][Full Text] [Related]
19. Molecular determinants for the high constitutive activity of the human histamine H4 receptor: functional studies on orthologues and mutants.
Wifling D; Löffel K; Nordemann U; Strasser A; Bernhardt G; Dove S; Seifert R; Buschauer A
Br J Pharmacol; 2015 Feb; 172(3):785-98. PubMed ID: 24903527
[TBL] [Abstract][Full Text] [Related]
20. Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics.
Wittmann HJ; Strasser A
Bioorg Med Chem Lett; 2015 Mar; 25(6):1259-68. PubMed ID: 25677665
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]