BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 18636744)

  • 1. Identification of tyrosine 972 as a novel site of Jak2 tyrosine kinase phosphorylation and its role in Jak2 activation.
    McDoom I; Ma X; Kirabo A; Lee KY; Ostrov DA; Sayeski PP
    Biochemistry; 2008 Aug; 47(32):8326-34. PubMed ID: 18636744
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of Y372 is critical for Jak2 tyrosine kinase activation.
    Sayyah J; Gnanasambandan K; Kamarajugadda S; Tsuda S; Caldwell-Busby J; Sayeski PP
    Cell Signal; 2011 Nov; 23(11):1806-15. PubMed ID: 21726629
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation.
    Xie S; Wang Y; Liu J; Sun T; Wilson MB; Smithgall TE; Arlinghaus RB
    Oncogene; 2001 Sep; 20(43):6188-95. PubMed ID: 11593427
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop.
    Feng J; Witthuhn BA; Matsuda T; Kohlhuber F; Kerr IM; Ihle JN
    Mol Cell Biol; 1997 May; 17(5):2497-501. PubMed ID: 9111318
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tyrosines 868, 966, and 972 in the kinase domain of JAK2 are autophosphorylated and required for maximal JAK2 kinase activity.
    Argetsinger LS; Stuckey JA; Robertson SA; Koleva RI; Cline JM; Marto JA; Myers MG; Carter-Su C
    Mol Endocrinol; 2010 May; 24(5):1062-76. PubMed ID: 20304997
    [TBL] [Abstract][Full Text] [Related]  

  • 6. JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functions.
    Rider L; Shatrova A; Feener EP; Webb L; Diakonova M
    J Biol Chem; 2007 Oct; 282(42):30985-96. PubMed ID: 17726028
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Three Tyrosine Residues in the Erythropoietin Receptor Are Essential for Janus Kinase 2 V617F Mutant-induced Tumorigenesis.
    Ueda F; Tago K; Tamura H; Funakoshi-Tago M
    J Biol Chem; 2017 Feb; 292(5):1826-1846. PubMed ID: 27998978
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2.
    VanderKuur J; Allevato G; Billestrup N; Norstedt G; Carter-Su C
    J Biol Chem; 1995 Mar; 270(13):7587-93. PubMed ID: 7535773
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling.
    Rui L; Mathews LS; Hotta K; Gustafson TA; Carter-Su C
    Mol Cell Biol; 1997 Nov; 17(11):6633-44. PubMed ID: 9343427
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Specific dephosphorylation of Janus Kinase 2 by protein tyrosine phosphatases.
    Li J; Liu X; Chu H; Fu X; Li T; Hu L; Xing S; Li G; Gu J; Zhao ZJ
    Proteomics; 2015 Jan; 15(1):68-76. PubMed ID: 25354842
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation.
    Hammarén HM; Ungureanu D; Grisouard J; Skoda RC; Hubbard SR; Silvennoinen O
    Proc Natl Acad Sci U S A; 2015 Apr; 112(15):4642-7. PubMed ID: 25825724
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase.
    Yi W; Kim SO; Jiang J; Park SH; Kraft AS; Waxman DJ; Frank SJ
    Mol Endocrinol; 1996 Nov; 10(11):1425-43. PubMed ID: 8923468
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase.
    Yamauchi T; Kaburagi Y; Ueki K; Tsuji Y; Stark GR; Kerr IM; Tsushima T; Akanuma Y; Komuro I; Tobe K; Yazaki Y; Kadowaki T
    J Biol Chem; 1998 Jun; 273(25):15719-26. PubMed ID: 9624169
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tyrosine phosphorylation of the Janus kinase 2 activation loop is essential for a high-activity catalytic state but dispensable for a basal catalytic state.
    Chatti K; Farrar WL; Duhé RJ
    Biochemistry; 2004 Apr; 43(14):4272-83. PubMed ID: 15065871
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Akt activation through the phosphorylation of erythropoietin receptor at tyrosine 479 is required for myeloproliferative disorder-associated JAK2 V617F mutant-induced cellular transformation.
    Kamishimoto J; Tago K; Kasahara T; Funakoshi-Tago M
    Cell Signal; 2011 May; 23(5):849-56. PubMed ID: 21255641
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tyrosine 813 is a site of JAK2 autophosphorylation critical for activation of JAK2 by SH2-B beta.
    Kurzer JH; Argetsinger LS; Zhou YJ; Kouadio JL; O'Shea JJ; Carter-Su C
    Mol Cell Biol; 2004 May; 24(10):4557-70. PubMed ID: 15121872
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity.
    Argetsinger LS; Kouadio JL; Steen H; Stensballe A; Jensen ON; Carter-Su C
    Mol Cell Biol; 2004 Jun; 24(11):4955-67. PubMed ID: 15143187
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Growth hormone-dependent phosphorylation of tyrosine 333 and/or 338 of the growth hormone receptor.
    VanderKuur JA; Wang X; Zhang L; Allevato G; Billestrup N; Carter-Su C
    J Biol Chem; 1995 Sep; 270(37):21738-44. PubMed ID: 7545168
    [TBL] [Abstract][Full Text] [Related]  

  • 19. JAK2 tyrosine kinase phosphorylates and is negatively regulated by centrosomal protein Ninein.
    Jay J; Hammer A; Nestor-Kalinoski A; Diakonova M
    Mol Cell Biol; 2015 Jan; 35(1):111-31. PubMed ID: 25332239
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of JAK2 protein expression by chronic, pulsatile GH administration in vivo: a possible mechanism for ligand enhancement of signal transduction.
    Zhou Y; Wang X; Hadley J; Corey SJ; Vasilatos-Younken R
    Gen Comp Endocrinol; 2005 Nov; 144(2):128-39. PubMed ID: 15993410
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.