BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

538 related articles for article (PubMed ID: 18639543)

  • 1. A quassinoid 6alpha-tigloyloxychaparrinone inhibits hypoxia-inducible factor-1 pathway by inhibition of eukaryotic translation initiation factor 4E phosphorylation.
    Jin X; Jin HR; Lee D; Lee JH; Kim SK; Lee JJ
    Eur J Pharmacol; 2008 Sep; 592(1-3):41-7. PubMed ID: 18639543
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy.
    García-Maceira P; Mateo J
    Oncogene; 2009 Jan; 28(3):313-24. PubMed ID: 18978810
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A hypoxia-driven vascular endothelial growth factor/Flt1 autocrine loop interacts with hypoxia-inducible factor-1alpha through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 pathway in neuroblastoma.
    Das B; Yeger H; Tsuchida R; Torkin R; Gee MF; Thorner PS; Shibuya M; Malkin D; Baruchel S
    Cancer Res; 2005 Aug; 65(16):7267-75. PubMed ID: 16103078
    [TBL] [Abstract][Full Text] [Related]  

  • 4. YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia.
    Sun HL; Liu YN; Huang YT; Pan SL; Huang DY; Guh JH; Lee FY; Kuo SC; Teng CM
    Oncogene; 2007 Jun; 26(27):3941-51. PubMed ID: 17213816
    [TBL] [Abstract][Full Text] [Related]  

  • 5. trans-3,4,5'-Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells.
    Cao Z; Fang J; Xia C; Shi X; Jiang BH
    Clin Cancer Res; 2004 Aug; 10(15):5253-63. PubMed ID: 15297429
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.
    Merighi S; Benini A; Mirandola P; Gessi S; Varani K; Simioni C; Leung E; Maclennan S; Baraldi PG; Borea PA
    Mol Pharmacol; 2007 Aug; 72(2):395-406. PubMed ID: 17488804
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Adenosine modulates vascular endothelial growth factor expression via hypoxia-inducible factor-1 in human glioblastoma cells.
    Merighi S; Benini A; Mirandola P; Gessi S; Varani K; Leung E; Maclennan S; Borea PA
    Biochem Pharmacol; 2006 Jun; 72(1):19-31. PubMed ID: 16682012
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Relationship between hypoxia-inducible factor-1alpha expression and extracellular signal-regulated kinase in hypoxic-ischemic cortical neurons].
    Zhang L; Qu Y; Zhang X; Yang C; Mao M; Mu D
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2009 Aug; 23(8):954-8. PubMed ID: 19728613
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The requirement of extracellular signal-related protein kinase pathway in the activation of hypoxia inducible factor 1 alpha in the developing rat brain after hypoxia-ischemia.
    Li L; Xiong Y; Qu Y; Mao M; Mu W; Wang H; Mu D
    Acta Neuropathol; 2008 Mar; 115(3):297-303. PubMed ID: 18210138
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combination strategy targeting the hypoxia inducible factor-1 alpha with mammalian target of rapamycin and histone deacetylase inhibitors.
    Verheul HM; Salumbides B; Van Erp K; Hammers H; Qian DZ; Sanni T; Atadja P; Pili R
    Clin Cancer Res; 2008 Jun; 14(11):3589-97. PubMed ID: 18519793
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways.
    Mi C; Ma J; Wang KS; Zuo HX; Wang Z; Li MY; Piao LX; Xu GH; Li X; Quan ZS; Jin X
    J Ethnopharmacol; 2017 May; 203():27-38. PubMed ID: 28341244
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isoflurane preconditioning activates HIF-1alpha, iNOS and Erk1/2 and protects against oxygen-glucose deprivation neuronal injury.
    Li QF; Zhu YS; Jiang H
    Brain Res; 2008 Dec; 1245():26-35. PubMed ID: 18930717
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling.
    Wang Y; Zhao Q; Ma S; Yang F; Gong Y; Ke C
    IUBMB Life; 2007 Nov; 59(11):717-21. PubMed ID: 17968710
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Therapeutic strategy targeting the mTOR-HIF-1alpha-VEGF pathway in ovarian clear cell adenocarcinoma.
    Miyazawa M; Yasuda M; Fujita M; Kajiwara H; Hirabayashi K; Takekoshi S; Hirasawa T; Murakami M; Ogane N; Kiguchi K; Ishiwata I; Mikami M; Osamura RY
    Pathol Int; 2009 Jan; 59(1):19-27. PubMed ID: 19121088
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Celastrol inhibits the HIF-1α pathway by inhibition of mTOR/p70S6K/eIF4E and ERK1/2 phosphorylation in human hepatoma cells.
    Ma J; Han LZ; Liang H; Mi C; Shi H; Lee JJ; Jin X
    Oncol Rep; 2014 Jul; 32(1):235-42. PubMed ID: 24859482
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ascochlorin inhibits growth factor-induced HIF-1α activation and tumor-angiogenesis through the suppression of EGFR/ERK/p70S6K signaling pathway in human cervical carcinoma cells.
    Jeong JH; Jeong YJ; Cho HJ; Shin JM; Kang JH; Park KK; Park YY; Chung IK; Chang HW; Magae J
    J Cell Biochem; 2012 Apr; 113(4):1302-13. PubMed ID: 22109717
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer.
    Lee BL; Kim WH; Jung J; Cho SJ; Park JW; Kim J; Chung HY; Chang MS; Nam SY
    Carcinogenesis; 2008 Jan; 29(1):44-51. PubMed ID: 17984117
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α.
    Ma J; Zi Jiang Y; Shi H; Mi C; Li J; Xing Nan J; Wu X; Joon Lee J; Jin X
    Eur J Pharmacol; 2014 Jan; 723():46-54. PubMed ID: 24333213
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation by NSC 644221.
    Creighton-Gutteridge M; Cardellina JH; Stephen AG; Rapisarda A; Uranchimeg B; Hite K; Denny WA; Shoemaker RH; Melillo G
    Clin Cancer Res; 2007 Feb; 13(3):1010-8. PubMed ID: 17289897
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of ERK and calcium in the hypoxia-induced activation of HIF-1.
    Mottet D; Michel G; Renard P; Ninane N; Raes M; Michiels C
    J Cell Physiol; 2003 Jan; 194(1):30-44. PubMed ID: 12447987
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.