BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 18641004)

  • 1. Telomere shortening is correlated with the DNA damage response and telomeric protein down-regulation in colorectal preneoplastic lesions.
    Raynaud CM; Jang SJ; Nuciforo P; Lantuejoul S; Brambilla E; Mounier N; Olaussen KA; André F; Morat L; Sabatier L; Soria JC
    Ann Oncol; 2008 Nov; 19(11):1875-81. PubMed ID: 18641004
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Telomere maintenance and DNA damage responses during lung carcinogenesis.
    Lantuejoul S; Raynaud C; Salameire D; Gazzeri S; Moro-Sibilot D; Soria JC; Brambilla C; Brambilla E
    Clin Cancer Res; 2010 Jun; 16(11):2979-88. PubMed ID: 20404006
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.
    Celli GB; de Lange T
    Nat Cell Biol; 2005 Jul; 7(7):712-8. PubMed ID: 15968270
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric cancer.
    Hu H; Zhang Y; Zou M; Yang S; Liang XQ
    J Cancer Res Clin Oncol; 2010 Sep; 136(9):1407-14. PubMed ID: 20127252
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells.
    Kishi S; Lu KP
    J Biol Chem; 2002 Mar; 277(9):7420-9. PubMed ID: 11744712
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.
    Martínez P; Flores JM; Blasco MA
    J Cell Biol; 2012 Apr; 197(2):283-300. PubMed ID: 22508511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons.
    Zhang P; Furukawa K; Opresko PL; Xu X; Bohr VA; Mattson MP
    J Neurochem; 2006 Apr; 97(2):567-81. PubMed ID: 16539655
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The shelterin protein TRF2 inhibits Chk2 activity at telomeres in the absence of DNA damage.
    Buscemi G; Zannini L; Fontanella E; Lecis D; Lisanti S; Delia D
    Curr Biol; 2009 May; 19(10):874-9. PubMed ID: 19375317
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
    Denchi EL; de Lange T
    Nature; 2007 Aug; 448(7157):1068-71. PubMed ID: 17687332
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response.
    Jullien L; Mestre M; Roux P; Gire V
    Nucleic Acids Res; 2013 Jan; 41(2):900-11. PubMed ID: 23193277
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Down-regulation of TRF1, TRF2 and TIN2 genes is important to maintain telomeric DNA for gastric cancers.
    Yamada M; Tsuji N; Nakamura M; Moriai R; Kobayashi D; Yagihashi A; Watanabe N
    Anticancer Res; 2002; 22(6A):3303-7. PubMed ID: 12530079
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation.
    Risques RA; Lai LA; Himmetoglu C; Ebaee A; Li L; Feng Z; Bronner MP; Al-Lahham B; Kowdley KV; Lindor KD; Rabinovitch PS; Brentnall TA
    Cancer Res; 2011 Mar; 71(5):1669-79. PubMed ID: 21363920
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA damage signaling is activated during cancer progression in human colorectal carcinoma.
    Oka K; Tanaka T; Enoki T; Yoshimura K; Ohshima M; Kubo M; Murakami T; Gondou T; Minami Y; Takemoto Y; Harada E; Tsushimi T; Li TS; Traganos F; Darzynkiewicz Z; Hamano K
    Cancer Biol Ther; 2010 Feb; 9(3):246-52. PubMed ID: 20023412
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Up-regulation of telomere-binding proteins, TRF1, TRF2, and TIN2 is related to telomere shortening during human multistep hepatocarcinogenesis.
    Oh BK; Kim YJ; Park C; Park YN
    Am J Pathol; 2005 Jan; 166(1):73-80. PubMed ID: 15632001
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA damage repair and telomere length in normal breast, preneoplastic lesions, and invasive cancer.
    Raynaud CM; Hernandez J; Llorca FP; Nuciforo P; Mathieu MC; Commo F; Delaloge S; Sabatier L; André F; Soria JC
    Am J Clin Oncol; 2010 Aug; 33(4):341-5. PubMed ID: 19884805
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect.
    Salvati E; Leonetti C; Rizzo A; Scarsella M; Mottolese M; Galati R; Sperduti I; Stevens MF; D'Incalci M; Blasco M; Chiorino G; Bauwens S; Horard B; Gilson E; Stoppacciaro A; Zupi G; Biroccio A
    J Clin Invest; 2007 Nov; 117(11):3236-47. PubMed ID: 17932567
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA damage drives an activin a-dependent induction of cyclooxygenase-2 in premalignant cells and lesions.
    Fordyce C; Fessenden T; Pickering C; Jung J; Singla V; Berman H; Tlsty T
    Cancer Prev Res (Phila); 2010 Feb; 3(2):190-201. PubMed ID: 20028875
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TRF2 promotes multidrug resistance in gastric cancer cells.
    Ning H; Li T; Zhao L; Li T; Li J; Liu J; Liu Z; Fan D
    Cancer Biol Ther; 2006 Aug; 5(8):950-6. PubMed ID: 16760674
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control.
    Wu Y; Xiao S; Zhu XD
    Nat Struct Mol Biol; 2007 Sep; 14(9):832-40. PubMed ID: 17694070
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA damage-induced phosphorylation of the human telomere-associated protein TRF2.
    Tanaka H; Mendonca MS; Bradshaw PS; Hoelz DJ; Malkas LH; Meyn MS; Gilley D
    Proc Natl Acad Sci U S A; 2005 Oct; 102(43):15539-44. PubMed ID: 16223874
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.