BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 18641359)

  • 1. The PDE4 inhibitor rolipram prevents NF-kappaB binding activity and proinflammatory cytokine release in human chorionic cells.
    Hervé R; Schmitz T; Evain-Brion D; Cabrol D; Leroy MJ; Méhats C
    J Immunol; 2008 Aug; 181(3):2196-202. PubMed ID: 18641359
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evidence for a role of phosphodiesterase 4 in lipopolysaccharide-stimulated prostaglandin E2 production and matrix metalloproteinase-9 activity in human amniochorionic membranes.
    Oger S; Méhats C; Dallot E; Cabrol D; Leroy MJ
    J Immunol; 2005 Jun; 174(12):8082-9. PubMed ID: 15944316
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PDE4 inhibition prevents preterm delivery induced by an intrauterine inflammation.
    Schmitz T; Souil E; Hervé R; Nicco C; Batteux F; Germain G; Cabrol D; Evain-Brion D; Leroy MJ; Méhats C
    J Immunol; 2007 Jan; 178(2):1115-21. PubMed ID: 17202375
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of type 4 cyclic nucleotide phosphodiesterase blocks intracellular TLR signaling in chronic lymphocytic leukemia and normal hematopoietic cells.
    Tan Y; Watkins AA; Freeman BB; Meyers JA; Rifkin IR; Lerner A
    J Immunol; 2015 Jan; 194(1):101-12. PubMed ID: 25416804
    [TBL] [Abstract][Full Text] [Related]  

  • 5. S-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway.
    Gobejishvili L; Avila DV; Barker DF; Ghare S; Henderson D; Brock GN; Kirpich IA; Joshi-Barve S; Mokshagundam SP; McClain CJ; Barve S
    J Pharmacol Exp Ther; 2011 May; 337(2):433-43. PubMed ID: 21266552
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNF alpha generation from human monocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer.
    Souness JE; Griffin M; Maslen C; Ebsworth K; Scott LC; Pollock K; Palfreyman MN; Karlsson JA
    Br J Pharmacol; 1996 Jun; 118(3):649-58. PubMed ID: 8762090
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production.
    Yougbaré I; Boire G; Roy M; Lugnier C; Rouseau E
    Can J Physiol Pharmacol; 2013 May; 91(5):353-61. PubMed ID: 23656347
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rolipram attenuates bile duct ligation-induced liver injury in rats: a potential pathogenic role of PDE4.
    Gobejishvili L; Barve S; Breitkopf-Heinlein K; Li Y; Zhang J; Avila DV; Dooley S; McClain CJ
    J Pharmacol Exp Ther; 2013 Oct; 347(1):80-90. PubMed ID: 23887098
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of rolipram, a selective inhibitor of type 4 phosphodiesterase, on lipopolysaccharide-induced uveitis in rats.
    Chi ZL; Hayasaka S; Zhang XY; Hayasaka Y; Cui HS
    Invest Ophthalmol Vis Sci; 2004 Aug; 45(8):2497-502. PubMed ID: 15277469
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease.
    Gobejishvili L; Barve S; Joshi-Barve S; McClain C
    Am J Physiol Gastrointest Liver Physiol; 2008 Oct; 295(4):G718-24. PubMed ID: 18687753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PDE4 inhibition drives resolution of neutrophilic inflammation by inducing apoptosis in a PKA-PI3K/Akt-dependent and NF-kappaB-independent manner.
    Sousa LP; Lopes F; Silva DM; Tavares LP; Vieira AT; Rezende BM; Carmo AF; Russo RC; Garcia CC; Bonjardim CA; Alessandri AL; Rossi AG; Pinho V; Teixeira MM
    J Leukoc Biol; 2010 May; 87(5):895-904. PubMed ID: 20103769
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Airway relaxant and anti-inflammatory properties of a PDE4 inhibitor with low affinity for the high-affinity rolipram binding site.
    Martin C; Göggel R; Dal Piaz V; Vergelli C; Giovannoni P; Ernst M; Uhlig S
    Naunyn Schmiedebergs Arch Pharmacol; 2002 Apr; 365(4):284-9. PubMed ID: 11919652
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shock.
    Link A; Selejan S; Maack C; Lenz M; Böhm M
    Crit Care; 2008; 12(6):R159. PubMed ID: 19091080
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Action of a Novel PDE4 inhibitor ZL-n-91 on lipopolysaccharide-induced acute lung injury.
    Tang HF; Lu JJ; Tang JF; Zheng X; Liang YQ; Wang XF; Wang YJ; Mao LG; Chen JQ
    Int Immunopharmacol; 2010 Apr; 10(4):406-11. PubMed ID: 20074667
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages.
    Yang JX; Hsieh KC; Chen YL; Lee CK; Conti M; Chuang TH; Wu CP; Jin SC
    Sci Rep; 2017 Apr; 7():46165. PubMed ID: 28383060
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1.
    Korhonen R; Hömmö T; Keränen T; Laavola M; Hämäläinen M; Vuolteenaho K; Lehtimäki L; Kankaanranta H; Moilanen E
    Br J Pharmacol; 2013 Aug; 169(7):1525-36. PubMed ID: 23849041
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro.
    Lappas M; Permezel M; Georgiou HM; Rice GE
    Biol Reprod; 2002 Aug; 67(2):668-73. PubMed ID: 12135912
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of phosphodiesterase-4 in the spinal dorsal horn ameliorates neuropathic pain via cAMP-cytokine-Cx43 signaling in mice.
    Zhang FF; Wang H; Zhou YM; Yu HY; Zhang M; Du X; Wang D; Zhang F; Xu Y; Zhang JG; Zhang HT
    CNS Neurosci Ther; 2022 May; 28(5):749-760. PubMed ID: 35156776
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues.
    Yougbare I; Morin C; Senouvo FY; Sirois C; Albadine R; Lugnier C; Rousseau E
    Am J Physiol Lung Cell Mol Physiol; 2011 Oct; 301(4):L441-50. PubMed ID: 21784969
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of NF-κB by Pyrrolidine Dithiocarbamate Prevents the Inflammatory Response in a Ligature-Induced Peri-Implantitis Model: A Canine Study.
    He CY; Jiang LP; Wang CY; Zhang Y
    Cell Physiol Biochem; 2018; 49(2):610-625. PubMed ID: 30165363
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.