BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

369 related articles for article (PubMed ID: 18642531)

  • 1. Controlling the selectivity and stability of proteins by new strategies in directed evolution: the case of organocatalytic enzymes.
    Reetz MT
    Ernst Schering Found Symp Proc; 2007; (2):321-40. PubMed ID: 18642531
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes.
    Reetz MT; Carballeira JD
    Nat Protoc; 2007; 2(4):891-903. PubMed ID: 17446890
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New Concepts for Increasing the Efficiency in Directed Evolution of Stereoselective Enzymes.
    Sun Z; Wikmark Y; Bäckvall JE; Reetz MT
    Chemistry; 2016 Apr; 22(15):5046-54. PubMed ID: 26914401
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein.
    Reetz MT; Peyralans JJ; Maichele A; Fu Y; Maywald M
    Chem Commun (Camb); 2006 Nov; (41):4318-20. PubMed ID: 17047853
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Laboratory evolution of stereoselective enzymes: a prolific source of catalysts for asymmetric reactions.
    Reetz MT
    Angew Chem Int Ed Engl; 2011 Jan; 50(1):138-74. PubMed ID: 20715024
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Directed evolution of enantioselective enzymes: an unconventional approach to asymmetric catalysis in organic chemistry.
    Reetz MT
    J Org Chem; 2009 Aug; 74(16):5767-78. PubMed ID: 20560561
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Iterative saturation mutagenesis accelerates laboratory evolution of enzyme stereoselectivity: rigorous comparison with traditional methods.
    Reetz MT; Prasad S; Carballeira JD; Gumulya Y; Bocola M
    J Am Chem Soc; 2010 Jul; 132(26):9144-52. PubMed ID: 20536132
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Many pathways in laboratory evolution can lead to improved enzymes: how to escape from local minima.
    Gumulya Y; Sanchis J; Reetz MT
    Chembiochem; 2012 May; 13(7):1060-6. PubMed ID: 22522601
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Controlling the enantioselectivity of enzymes by directed evolution: practical and theoretical ramifications.
    Reetz MT
    Proc Natl Acad Sci U S A; 2004 Apr; 101(16):5716-22. PubMed ID: 15079053
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Shedding light on the efficacy of laboratory evolution based on iterative saturation mutagenesis.
    Reetz MT; Kahakeaw D; Sanchis J
    Mol Biosyst; 2009 Feb; 5(2):115-22. PubMed ID: 19156255
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Manipulating the stereoselectivity of limonene epoxide hydrolase by directed evolution based on iterative saturation mutagenesis.
    Zheng H; Reetz MT
    J Am Chem Soc; 2010 Nov; 132(44):15744-51. PubMed ID: 20958062
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Directed evolution of enzymes for applied biocatalysis.
    Turner NJ
    Trends Biotechnol; 2003 Nov; 21(11):474-8. PubMed ID: 14573359
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Directed evolution of enantioselective enzymes: iterative cycles of CASTing for probing protein-sequence space.
    Reetz MT; Wang LW; Bocola M
    Angew Chem Int Ed Engl; 2006 Feb; 45(8):1236-41. PubMed ID: 16411254
    [No Abstract]   [Full Text] [Related]  

  • 14. Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage.
    Reetz MT; Bocola M; Wang LW; Sanchis J; Cronin A; Arand M; Zou J; Archelas A; Bottalla AL; Naworyta A; Mowbray SL
    J Am Chem Soc; 2009 Jun; 131(21):7334-43. PubMed ID: 19469578
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Addressing the numbers problem in directed evolution.
    Reetz MT; Kahakeaw D; Lohmer R
    Chembiochem; 2008 Jul; 9(11):1797-804. PubMed ID: 18567049
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enantioselective biocatalysis optimized by directed evolution.
    Jaeger KE; Eggert T
    Curr Opin Biotechnol; 2004 Aug; 15(4):305-13. PubMed ID: 15358000
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biomimetic organocatalytic C-C-bond formations.
    Enders D; Hüttl MR; Niemeier O
    Ernst Schering Found Symp Proc; 2007; (2):45-124. PubMed ID: 18642522
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Engineered enzymes for improved organic synthesis.
    Hult K; Berglund P
    Curr Opin Biotechnol; 2003 Aug; 14(4):395-400. PubMed ID: 12943848
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Altering protein specificity: techniques and applications.
    Antikainen NM; Martin SF
    Bioorg Med Chem; 2005 Apr; 13(8):2701-16. PubMed ID: 15781382
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Iterative saturation mutagenesis: a powerful approach to engineer proteins by systematically simulating Darwinian evolution.
    Acevedo-Rocha CG; Hoebenreich S; Reetz MT
    Methods Mol Biol; 2014; 1179():103-28. PubMed ID: 25055773
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.