These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
152 related articles for article (PubMed ID: 18644784)
1. Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter. Ozvegy-Laczka C; Laczkó R; Hegedus C; Litman T; Várady G; Goda K; Hegedus T; Dokholyan NV; Sorrentino BP; Váradi A; Sarkadi B J Biol Chem; 2008 Sep; 283(38):26059-70. PubMed ID: 18644784 [TBL] [Abstract][Full Text] [Related]
2. Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2. Henriksen U; Fog JU; Litman T; Gether U J Biol Chem; 2005 Nov; 280(44):36926-34. PubMed ID: 16107343 [TBL] [Abstract][Full Text] [Related]
3. Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface. Ozvegy-Laczka C; Várady G; Köblös G; Ujhelly O; Cervenak J; Schuetz JD; Sorrentino BP; Koomen GJ; Váradi A; Német K; Sarkadi B J Biol Chem; 2005 Feb; 280(6):4219-27. PubMed ID: 15557326 [TBL] [Abstract][Full Text] [Related]
4. Oligomerization of the human ABC transporter ABCG2: evaluation of the native protein and chimeric dimers. Bhatia A; Schäfer HJ; Hrycyna CA Biochemistry; 2005 Aug; 44(32):10893-904. PubMed ID: 16086592 [TBL] [Abstract][Full Text] [Related]
5. Intramolecular disulfide bond is a critical check point determining degradative fates of ATP-binding cassette (ABC) transporter ABCG2 protein. Wakabayashi K; Nakagawa H; Tamura A; Koshiba S; Hoshijima K; Komada M; Ishikawa T J Biol Chem; 2007 Sep; 282(38):27841-6. PubMed ID: 17686774 [TBL] [Abstract][Full Text] [Related]
6. Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2. Polgar O; Ierano C; Tamaki A; Stanley B; Ward Y; Xia D; Tarasova N; Robey RW; Bates SE Biochemistry; 2010 Mar; 49(10):2235-45. PubMed ID: 20088606 [TBL] [Abstract][Full Text] [Related]
7. Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2. Shukla S; Robey RW; Bates SE; Ambudkar SV Drug Metab Dispos; 2009 Feb; 37(2):359-65. PubMed ID: 18971320 [TBL] [Abstract][Full Text] [Related]
8. Identification of cysteine residues critically involved in homodimer formation and protein expression of human ATP-binding cassette transporter ABCG2: a new approach using the flp recombinase system. Wakabayashi K; Nakagawa H; Adachi T; Kii I; Kobatake E; Kudo A; Ishikawa T J Exp Ther Oncol; 2006; 5(3):205-22. PubMed ID: 16528971 [TBL] [Abstract][Full Text] [Related]
9. Effect of cysteine mutagenesis on the function and disulfide bond formation of human ABCG2. Liu Y; Yang Y; Qi J; Peng H; Zhang JT J Pharmacol Exp Ther; 2008 Jul; 326(1):33-40. PubMed ID: 18430864 [TBL] [Abstract][Full Text] [Related]
10. The nature of amino acid 482 of human ABCG2 affects substrate transport and ATP hydrolysis but not substrate binding. Ejendal KF; Diop NK; Schweiger LC; Hrycyna CA Protein Sci; 2006 Jul; 15(7):1597-607. PubMed ID: 16815914 [TBL] [Abstract][Full Text] [Related]
11. Identification of proline residues in or near the transmembrane helices of the human breast cancer resistance protein (BCRP/ABCG2) that are important for transport activity and substrate specificity. Ni Z; Bikadi Z; Shuster DL; Zhao C; Rosenberg MF; Mao Q Biochemistry; 2011 Sep; 50(37):8057-66. PubMed ID: 21854076 [TBL] [Abstract][Full Text] [Related]
12. Endocytosis of ABCG2 drug transporter caused by binding of 5D3 antibody: trafficking mechanisms and intracellular fate. Studzian M; Bartosz G; Pulaski L Biochim Biophys Acta; 2015 Aug; 1853(8):1759-71. PubMed ID: 25918011 [TBL] [Abstract][Full Text] [Related]
13. Mutational studies of G553 in TM5 of ABCG2: a residue potentially involved in dimerization. Polgar O; Ozvegy-Laczka C; Robey RW; Morisaki K; Okada M; Tamaki A; Koblos G; Elkind NB; Ward Y; Dean M; Sarkadi B; Bates SE Biochemistry; 2006 Apr; 45(16):5251-60. PubMed ID: 16618113 [TBL] [Abstract][Full Text] [Related]
14. Role of Cys-603 in dimer/oligomer formation of the breast cancer resistance protein BCRP/ABCG2. Kage K; Fujita T; Sugimoto Y Cancer Sci; 2005 Dec; 96(12):866-72. PubMed ID: 16367905 [TBL] [Abstract][Full Text] [Related]
15. Oligomerization domain of the multidrug resistance-associated transporter ABCG2 and its dominant inhibitory activity. Xu J; Peng H; Chen Q; Liu Y; Dong Z; Zhang JT Cancer Res; 2007 May; 67(9):4373-81. PubMed ID: 17483351 [TBL] [Abstract][Full Text] [Related]
16. Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2. Xu J; Liu Y; Yang Y; Bates S; Zhang JT J Biol Chem; 2004 May; 279(19):19781-9. PubMed ID: 15001581 [TBL] [Abstract][Full Text] [Related]
17. Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter. Telbisz Á; Hegedüs C; Özvegy-Laczka C; Goda K; Várady G; Takáts Z; Szabó E; Sorrentino BP; Váradi A; Sarkadi B Eur J Pharm Sci; 2012 Jan; 45(1-2):101-9. PubMed ID: 22115866 [TBL] [Abstract][Full Text] [Related]
18. Regulation of the function of the human ABCG2 multidrug transporter by cholesterol and bile acids: effects of mutations in potential substrate and steroid binding sites. Telbisz Á; Hegedüs C; Váradi A; Sarkadi B; Özvegy-Laczka C Drug Metab Dispos; 2014 Apr; 42(4):575-85. PubMed ID: 24384916 [TBL] [Abstract][Full Text] [Related]
19. Multidrug resistance in cancer chemotherapy and xenobiotic protection mediated by the half ATP-binding cassette transporter ABCG2. Han B; Zhang JT Curr Med Chem Anticancer Agents; 2004 Jan; 4(1):31-42. PubMed ID: 14754410 [TBL] [Abstract][Full Text] [Related]
20. Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation. Ozvegy C; Váradi A; Sarkadi B J Biol Chem; 2002 Dec; 277(50):47980-90. PubMed ID: 12374800 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]