BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 18645030)

  • 1. The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.
    Raja SM; Chen S; Yue P; Acker TM; Lefkove B; Arbiser JL; Khuri FR; Sun SY
    Mol Cancer Ther; 2008 Jul; 7(7):2212-23. PubMed ID: 18645030
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells.
    Chen S; Liu X; Yue P; Schönthal AH; Khuri FR; Sun SY
    Mol Pharmacol; 2007 Nov; 72(5):1269-79. PubMed ID: 17684158
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation.
    Fan S; Li Y; Yue P; Khuri FR; Sun SY
    Neoplasia; 2010 Apr; 12(4):346-56. PubMed ID: 20360945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells.
    Zou W; Chen S; Liu X; Yue P; Sporn MB; Khuri FR; Sun SY
    Cancer Biol Ther; 2007 Oct; 6(10):1614-20. PubMed ID: 18253090
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
    Elrod HA; Lin YD; Yue P; Wang X; Lonial S; Khuri FR; Sun SY
    Mol Cancer Ther; 2007 Jul; 6(7):2029-38. PubMed ID: 17604333
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Honokiol Enhances TRAIL-Mediated Apoptosis through STAMBPL1-Induced Survivin and c-FLIP Degradation.
    Woo SM; Seo SU; Kubatka P; Min KJ; Kwon TK
    Biomolecules; 2019 Dec; 9(12):. PubMed ID: 31817770
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dissecting the roles of DR4, DR5 and c-FLIP in the regulation of geranylgeranyltransferase I inhibition-mediated augmentation of TRAIL-induced apoptosis.
    Chen S; Fu L; Raja SM; Yue P; Khuri FR; Sun SY
    Mol Cancer; 2010 Jan; 9():23. PubMed ID: 20113484
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells.
    Woo SM; Min KJ; Kwon TK
    Molecules; 2020 Oct; 25(19):. PubMed ID: 33050112
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Involvement of c-FLIP and survivin down-regulation in flexible heteroarotinoid-induced apoptosis and enhancement of TRAIL-initiated apoptosis in lung cancer cells.
    Lin Y; Liu X; Yue P; Benbrook DM; Berlin KD; Khuri FR; Sun SY
    Mol Cancer Ther; 2008 Nov; 7(11):3556-65. PubMed ID: 19001438
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cellular FLICE-inhibitory protein down-regulation contributes to celecoxib-induced apoptosis in human lung cancer cells.
    Liu X; Yue P; Schönthal AH; Khuri FR; Sun SY
    Cancer Res; 2006 Dec; 66(23):11115-9. PubMed ID: 17145853
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metformin sensitizes human bladder cancer cells to TRAIL-induced apoptosis through mTOR/S6K1-mediated downregulation of c-FLIP.
    Zhang T; Wang X; He D; Jin X; Guo P
    Anticancer Drugs; 2014 Sep; 25(8):887-97. PubMed ID: 24714080
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells.
    Wang P; Zhang J; Bellail A; Jiang W; Hugh J; Kneteman NM; Hao C
    Cell Signal; 2007 Nov; 19(11):2237-46. PubMed ID: 17693058
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Codium fragile F2 sensitize colorectal cancer cells to TRAIL-induced apoptosis via c-FLIP ubiquitination.
    Park SH; Kim JL; Jeong S; Kim BR; Na YJ; Jo MJ; Yun HK; Jeong YA; Kim DY; Kim BG; You S; Oh SC; Lee DH
    Biochem Biophys Res Commun; 2019 Jan; 508(1):1-8. PubMed ID: 30409427
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CK2 controls TRAIL and Fas sensitivity by regulating FLIP levels in endometrial carcinoma cells.
    Llobet D; Eritja N; Encinas M; Llecha N; Yeramian A; Pallares J; Sorolla A; Gonzalez-Tallada FJ; Matias-Guiu X; Dolcet X
    Oncogene; 2008 Apr; 27(18):2513-24. PubMed ID: 17982483
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The NEDD8-activating enzyme inhibitor, MLN4924, cooperates with TRAIL to augment apoptosis through facilitating c-FLIP degradation in head and neck cancer cells.
    Zhao L; Yue P; Lonial S; Khuri FR; Sun SY
    Mol Cancer Ther; 2011 Dec; 10(12):2415-25. PubMed ID: 21914854
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Calyculin A causes sensitization to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by ROS-mediated down-regulation of cellular FLICE-inhibiting protein (c-FLIP) and by enhancing death receptor 4 mRNA stabilization.
    Woo SM; Min KJ; Kwon TK
    Apoptosis; 2012 Nov; 17(11):1223-34. PubMed ID: 22911475
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective inhibition of FLICE-like inhibitory protein expression with small interfering RNA oligonucleotides is sufficient to sensitize tumor cells for TRAIL-induced apoptosis.
    Siegmund D; Hadwiger P; Pfizenmaier K; Vornlocher HP; Wajant H
    Mol Med; 2002 Nov; 8(11):725-32. PubMed ID: 12520089
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hyperthermia restores apoptosis induced by death receptors through aggregation-induced c-FLIP cytosolic depletion.
    Morlé A; Garrido C; Micheau O
    Cell Death Dis; 2015 Feb; 6(2):e1633. PubMed ID: 25675293
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Flavopiridol induces cellular FLICE-inhibitory protein degradation by the proteasome and promotes TRAIL-induced early signaling and apoptosis in breast tumor cells.
    Palacios C; Yerbes R; López-Rivas A
    Cancer Res; 2006 Sep; 66(17):8858-69. PubMed ID: 16951203
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.
    Liu X; Yue P; Chen S; Hu L; Lonial S; Khuri FR; Sun SY
    Cancer Res; 2007 May; 67(10):4981-8. PubMed ID: 17510429
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.