BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

594 related articles for article (PubMed ID: 18646811)

  • 1. Small-angle X-ray scattering studies on structures of an estrogen-related receptor alpha ligand binding domain and its complexes with ligands and coactivators.
    Jin KS; Park JK; Yoon J; Rho Y; Kim JH; Kim EE; Ree M
    J Phys Chem B; 2008 Aug; 112(32):9603-12. PubMed ID: 18646811
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of ligand binding on the association properties and conformation in solution of retinoic acid receptors RXR and RAR.
    Egea PF; Rochel N; Birck C; Vachette P; Timmins PA; Moras D
    J Mol Biol; 2001 Mar; 307(2):557-76. PubMed ID: 11254382
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
    Nascimento AS; Dias SM; Nunes FM; Aparício R; Ambrosio AL; Bleicher L; Figueira AC; Santos MA; de Oliveira Neto M; Fischer H; Togashi M; Craievich AF; Garratt RC; Baxter JD; Webb P; Polikarpov I
    J Mol Biol; 2006 Jul; 360(3):586-98. PubMed ID: 16781732
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.
    Nolte RT; Wisely GB; Westin S; Cobb JE; Lambert MH; Kurokawa R; Rosenfeld MG; Willson TM; Glass CK; Milburn MV
    Nature; 1998 Sep; 395(6698):137-43. PubMed ID: 9744270
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of the rat alpha 1 thyroid hormone receptor ligand binding domain in Escherichia coli and the use of a ligand-induced conformation change as a method for its purification to homogeneity.
    Apriletti JW; Baxter JD; Lau KH; West BL
    Protein Expr Purif; 1995 Jun; 6(3):363-70. PubMed ID: 7663174
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and in vitro biological evaluation of small molecule inhibitors of estrogen receptor alpha coactivator binding.
    Rodriguez AL; Tamrazi A; Collins ML; Katzenellenbogen JA
    J Med Chem; 2004 Jan; 47(3):600-11. PubMed ID: 14736241
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide.
    Vanhooke JL; Benning MM; Bauer CB; Pike JW; DeLuca HF
    Biochemistry; 2004 Apr; 43(14):4101-10. PubMed ID: 15065852
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Conformational dynamics of the estrogen receptor alpha: molecular dynamics simulations of the influence of binding site structure on protein dynamics.
    Celik L; Lund JD; Schiøtt B
    Biochemistry; 2007 Feb; 46(7):1743-58. PubMed ID: 17249692
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exploring the binding site structure of the PPAR gamma ligand-binding domain by computational solvent mapping.
    Sheu SH; Kaya T; Waxman DJ; Vajda S
    Biochemistry; 2005 Feb; 44(4):1193-209. PubMed ID: 15667213
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Three-dimensional model of the ligand binding domain of the nuclear receptor for 1alpha,25-dihydroxy-vitamin D(3).
    Norman AW; Adams D; Collins ED; Okamura WH; Fletterick RJ
    J Cell Biochem; 1999 Sep; 74(3):323-33. PubMed ID: 10412035
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression, purification, and initial structural characterization of rat orphan nuclear receptor NOR-1 LBD domain.
    Razzera G; Vernal J; Portugal RV; Calgaro MR; Fernandez P; Zakin MM; Polikarpov I; Terenzi H
    Protein Expr Purif; 2004 Oct; 37(2):443-9. PubMed ID: 15358368
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence for ligand-independent transcriptional activation of the human estrogen-related receptor alpha (ERRalpha): crystal structure of ERRalpha ligand binding domain in complex with peroxisome proliferator-activated receptor coactivator-1alpha.
    Kallen J; Schlaeppi JM; Bitsch F; Filipuzzi I; Schilb A; Riou V; Graham A; Strauss A; Geiser M; Fournier B
    J Biol Chem; 2004 Nov; 279(47):49330-7. PubMed ID: 15337744
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
    Shiau AK; Barstad D; Radek JT; Meyers MJ; Nettles KW; Katzenellenbogen BS; Katzenellenbogen JA; Agard DA; Greene GL
    Nat Struct Biol; 2002 May; 9(5):359-64. PubMed ID: 11953755
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Monitoring ligand modulation of protein-protein interactions by mass spectrometry: estrogen receptor alpha-SRC1.
    Bovet C; Ruff M; Eiler S; Granger F; Wenzel R; Nazabal A; Moras D; Zenobi R
    Anal Chem; 2008 Oct; 80(20):7833-9. PubMed ID: 18778086
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Solution X-ray scattering reveals a novel structure of calmodulin complexed with a binding domain peptide from the HIV-1 matrix protein p17.
    Izumi Y; Watanabe H; Watanabe N; Aoyama A; Jinbo Y; Hayashi N
    Biochemistry; 2008 Jul; 47(27):7158-66. PubMed ID: 18553937
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RARbeta ligand-binding domain bound to an SRC-1 co-activator peptide: purification, crystallization and preliminary X-ray diffraction analysis.
    Kammerer S; Germain P; Flaig R; Peluso-Iltis C; Mitschler A; Rochel N; Gronemeyer H; Moras D
    Acta Crystallogr D Biol Crystallogr; 2004 Nov; 60(Pt 11):2048-50. PubMed ID: 15502323
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity.
    Solomon IH; Hager JM; Safi R; McDonnell DP; Redinbo MR; Ortlund EA
    J Mol Biol; 2005 Dec; 354(5):1091-102. PubMed ID: 16289203
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular dynamics simulation of the ligand binding domain of farnesoid X receptor. Insights into helix-12 stability and coactivator peptide stabilization in response to agonist binding.
    Costantino G; Entrena-Guadix A; Macchiarulo A; Gioiello A; Pellicciari R
    J Med Chem; 2005 May; 48(9):3251-9. PubMed ID: 15857131
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rational discovery of a novel interface for a coactivator in the peroxisome proliferator-activated receptor gamma: theoretical implications of impairment in type 2 diabetes mellitus.
    Shiraki T; Kodama TS; Jingami H; Kamiya N
    Proteins; 2005 Feb; 58(2):418-25. PubMed ID: 15558556
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ab initio quantum mechanical study of the binding energies of human estrogen receptor alpha with its ligands: an application of fragment molecular orbital method.
    Fukuzawa K; Kitaura K; Uebayasi M; Nakata K; Kaminuma T; Nakano T
    J Comput Chem; 2005 Jan; 26(1):1-10. PubMed ID: 15521089
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.