278 related articles for article (PubMed ID: 18651729)
1. Design, synthesis and biological evaluation of glutathione peptidomimetics as components of anti-Parkinson prodrugs.
More SS; Vince R
J Med Chem; 2008 Aug; 51(15):4581-8. PubMed ID: 18651729
[TBL] [Abstract][Full Text] [Related]
2. Large amino acid transporter 1 (LAT1) prodrugs of valproic acid: new prodrug design ideas for central nervous system delivery.
Peura L; Malmioja K; Laine K; Leppänen J; Gynther M; Isotalo A; Rautio J
Mol Pharm; 2011 Oct; 8(5):1857-66. PubMed ID: 21770378
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of L-dopa amide derivatives as potential prodrugs for the treatment of Parkinson's disease.
Zhou T; Hider RC; Jenner P; Campbell B; Hobbs CJ; Rose S; Jairaj M; Tayarani-Binazir KA; Syme A
Eur J Med Chem; 2010 Sep; 45(9):4035-42. PubMed ID: 20646792
[TBL] [Abstract][Full Text] [Related]
4. Glucose promoiety enables glucose transporter mediated brain uptake of ketoprofen and indomethacin prodrugs in rats.
Gynther M; Ropponen J; Laine K; Leppänen J; Haapakoski P; Peura L; Järvinen T; Rautio J
J Med Chem; 2009 May; 52(10):3348-53. PubMed ID: 19402664
[TBL] [Abstract][Full Text] [Related]
5. Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides.
Liederer BM; Fuchs T; Vander Velde D; Siahaan TJ; Borchardt RT
J Med Chem; 2006 Feb; 49(4):1261-70. PubMed ID: 16480263
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and in vitro studies on a potential dopamine prodrug.
Giannola LI; De Caro V; Giandalia G; Siragusa MG; Lamartina L
Pharmazie; 2008 Oct; 63(10):704-10. PubMed ID: 18972830
[TBL] [Abstract][Full Text] [Related]
7. Syntheses of cyclic prodrugs of RGD peptidomimetics with various macrocyclic ring sizes: evaluation of physicochemical, transport and antithrombic properties.
He HT; Xu CR; Song X; Siahaan TJ
J Pept Res; 2003 Jun; 61(6):331-42. PubMed ID: 12753380
[TBL] [Abstract][Full Text] [Related]
8. Targeting the delivery of glycan-based paclitaxel prodrugs to cancer cells via glucose transporters.
Lin YS; Tungpradit R; Sinchaikul S; An FM; Liu DZ; Phutrakul S; Chen ST
J Med Chem; 2008 Dec; 51(23):7428-41. PubMed ID: 19053781
[TBL] [Abstract][Full Text] [Related]
9. Prodrug design for brain delivery of small- and medium-sized neuropeptides.
Prokai-Tatrai K; Prokai L
Methods Mol Biol; 2011; 789():313-36. PubMed ID: 21922418
[TBL] [Abstract][Full Text] [Related]
10. Polycyclic cage structures as carrier molecules for neuroprotective non-steroidal anti-inflammatory drugs.
Prins LH; du Preez JL; van Dyk S; Malan SF
Eur J Med Chem; 2009 Jun; 44(6):2577-82. PubMed ID: 19233517
[TBL] [Abstract][Full Text] [Related]
11. Dipeptidomimetic ketomethylene isosteres as pro-moieties for drug transport via the human intestinal di-/tripeptide transporter hPEPT1: design, synthesis, stability, and biological investigations.
Våbenø J; Nielsen CU; Ingebrigtsen T; Lejon T; Steffansen B; Luthman K
J Med Chem; 2004 Sep; 47(19):4755-65. PubMed ID: 15341490
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and evaluation of novel prodrugs of caspase inhibitors.
Charrier JD; Durrant SJ; Studley J; Lawes L; Weber P
Bioorg Med Chem Lett; 2012 Jan; 22(1):485-8. PubMed ID: 22104150
[TBL] [Abstract][Full Text] [Related]
13. Application of a novel design paradigm to generate general nonpeptide combinatorial templates mimicking beta-turns: synthesis of ligands for melanocortin receptors.
Webb TR; Jiang L; Sviridov S; Venegas RE; Vlaskina AV; McGrath D; Tucker J; Wang J; Deschenes A; Li R
J Comb Chem; 2007; 9(4):704-10. PubMed ID: 17429950
[TBL] [Abstract][Full Text] [Related]
14. Metabolism evaluation of biomimetic prodrugs by in vitro models and mass spectrometry.
Lalanne M; Khoury H; Deroussent A; Bosquet N; Benech H; Clayette P; Couvreur P; Vassal G; Paci A; Andrieux K
Int J Pharm; 2009 Sep; 379(2):235-43. PubMed ID: 19467308
[TBL] [Abstract][Full Text] [Related]
15. Orally active oxime derivatives of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one. Synthesis and pharmacological activity.
Venhuis BJ; Dijkstra D; Wustrow D; Meltzer LT; Wise LD; Johnson SJ; Wikström HV
J Med Chem; 2003 Sep; 46(19):4136-40. PubMed ID: 12954065
[TBL] [Abstract][Full Text] [Related]
16. [Research of oral prodrugs: opportunities and challenges].
Cao F; Ping QN; Chen J
Yao Xue Xue Bao; 2008 Apr; 43(4):343-9. PubMed ID: 18664193
[TBL] [Abstract][Full Text] [Related]
17. [Synthesis of prodrugs of tacrine hydrochloride and evaluation of the stability and biodistribution in mice].
Jiang Y; Zhang Y; Zhang ZR
Yao Xue Xue Bao; 2003 Dec; 38(12):962-5. PubMed ID: 15040096
[TBL] [Abstract][Full Text] [Related]
18. Lipophilic pyrazinoic acid amide and ester prodrugs stability, activation and activity against M. tuberculosis.
Simões MF; Valente E; Gómez MJ; Anes E; Constantino L
Eur J Pharm Sci; 2009 Jun; 37(3-4):257-63. PubMed ID: 19491013
[TBL] [Abstract][Full Text] [Related]
19. Potential prodrugs of non-steroidal anti-inflammatory agents for targeted drug delivery to the CNS.
Perioli L; Ambrogi V; Bernardini C; Grandolini G; Ricci M; Giovagnoli S; Rossi C
Eur J Med Chem; 2004 Aug; 39(8):715-27. PubMed ID: 15276305
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and in vitro biological evaluation of mannose-containing prodrugs derived from clinically used HIV-protease inhibitors with improved transepithelial transport.
Roche D; Greiner J; Aubertin AM; Vierling P
Bioconjug Chem; 2006; 17(6):1568-81. PubMed ID: 17105238
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]