These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
212 related articles for article (PubMed ID: 18655141)
1. Structure-activity relationship and metabolic stability studies of backbone cyclization and N-methylation of melanocortin peptides. Linde Y; Ovadia O; Safrai E; Xiang Z; Portillo FP; Shalev DE; Haskell-Luevano C; Hoffman A; Gilon C Biopolymers; 2008; 90(5):671-82. PubMed ID: 18655141 [TBL] [Abstract][Full Text] [Related]
2. Backbone cyclic peptidomimetic melanocortin-4 receptor agonist as a novel orally administrated drug lead for treating obesity. Hess S; Linde Y; Ovadia O; Safrai E; Shalev DE; Swed A; Halbfinger E; Lapidot T; Winkler I; Gabinet Y; Faier A; Yarden D; Xiang Z; Portillo FP; Haskell-Luevano C; Gilon C; Hoffman A J Med Chem; 2008 Feb; 51(4):1026-34. PubMed ID: 18220330 [TBL] [Abstract][Full Text] [Related]
3. Effect of structural and conformation modifications, including backbone cyclization, of hydrophilic hexapeptides on their intestinal permeability and enzymatic stability. Hess S; Ovadia O; Shalev DE; Senderovich H; Qadri B; Yehezkel T; Salitra Y; Sheynis T; Jelinek R; Gilon C; Hoffman A J Med Chem; 2007 Nov; 50(24):6201-11. PubMed ID: 17983214 [TBL] [Abstract][Full Text] [Related]
4. The effect of backbone cyclization on PK/PD properties of bioactive peptide-peptoid hybrids: the melanocortin agonist paradigm. Ovadia O; Linde Y; Haskell-Luevano C; Dirain ML; Sheynis T; Jelinek R; Gilon C; Hoffman A Bioorg Med Chem; 2010 Jan; 18(2):580-9. PubMed ID: 20056544 [TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, structural and functional characterization of novel melanocortin agonists based on the cyclotide kalata B1. Eliasen R; Daly NL; Wulff BS; Andresen TL; Conde-Frieboes KW; Craik DJ J Biol Chem; 2012 Nov; 287(48):40493-501. PubMed ID: 23012369 [TBL] [Abstract][Full Text] [Related]
6. Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation. Qvit N; Kornfeld OS J Vis Exp; 2016 Jan; (107):e53589. PubMed ID: 26863382 [TBL] [Abstract][Full Text] [Related]
7. Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R. Balse-Srinivasan P; Grieco P; Cai M; Trivedi D; Hruby VJ J Med Chem; 2003 Aug; 46(17):3728-33. PubMed ID: 12904077 [TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological activity of NK-1 selective, N-backbone cyclic analogs of the C-terminal hexapeptide of substance P. Byk G; Halle D; Zeltser I; Bitan G; Selinger Z; Gilon C J Med Chem; 1996 Aug; 39(16):3174-8. PubMed ID: 8759639 [TBL] [Abstract][Full Text] [Related]
9. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands. Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118 [TBL] [Abstract][Full Text] [Related]
10. The Melanocortin Receptor System: A Target for Multiple Degenerative Diseases. Cai M; Hruby VJ Curr Protein Pept Sci; 2016; 17(5):488-96. PubMed ID: 26916163 [TBL] [Abstract][Full Text] [Related]
11. De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach. Han G; Haskell-Luevano C; Kendall L; Bonner G; Hadley ME; Cone RD; Hruby VJ J Med Chem; 2004 Mar; 47(6):1514-26. PubMed ID: 14998337 [TBL] [Abstract][Full Text] [Related]
12. Structure-activity relationships of the unique and potent agouti-related protein (AGRP)-melanocortin chimeric Tyr-c[beta-Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 peptide template. Wilczynski A; Wilson KR; Scott JW; Edison AS; Haskell-Luevano C J Med Chem; 2005 Apr; 48(8):3060-75. PubMed ID: 15828845 [TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological activities of new side chain and backbone cyclic bradykinin analogues. Schumann C; Seyfarth L; Greiner G; Paegelow I; Reissmann S J Pept Res; 2002 Aug; 60(2):128-40. PubMed ID: 12102726 [TBL] [Abstract][Full Text] [Related]
14. Multiple N-methylation of MT-II backbone amide bonds leads to melanocortin receptor subtype hMC1R selectivity: pharmacological and conformational studies. Doedens L; Opperer F; Cai M; Beck JG; Dedek M; Palmer E; Hruby VJ; Kessler H J Am Chem Soc; 2010 Jun; 132(23):8115-28. PubMed ID: 20496895 [TBL] [Abstract][Full Text] [Related]
15. Incorporation of a bioactive reverse-turn heterocycle into a peptide template using solid-phase synthesis to probe melanocortin receptor selectivity and ligand conformations by 2D 1H NMR. Singh A; Wilczynski A; Holder JR; Witek RM; Dirain ML; Xiang Z; Edison AS; Haskell-Luevano C J Med Chem; 2011 Mar; 54(5):1379-90. PubMed ID: 21306168 [TBL] [Abstract][Full Text] [Related]