BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 18655183)

  • 1. Quercetin suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha) through inhibiting protein synthesis.
    Lee DH; Lee YJ
    J Cell Biochem; 2008 Oct; 105(2):546-53. PubMed ID: 18655183
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.
    Park SS; Bae I; Lee YJ
    J Cell Biochem; 2008 Apr; 103(6):1989-98. PubMed ID: 17973296
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells.
    Gupta B; Chiang L; Chae K; Lee DH
    Food Chem; 2013 Dec; 141(3):1841-6. PubMed ID: 23870899
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Quercetin activates an angiogenic pathway, hypoxia inducible factor (HIF)-1-vascular endothelial growth factor, by inhibiting HIF-prolyl hydroxylase: a structural analysis of quercetin for inhibiting HIF-prolyl hydroxylase.
    Jeon H; Kim H; Choi D; Kim D; Park SY; Kim YJ; Kim YM; Jung Y
    Mol Pharmacol; 2007 Jun; 71(6):1676-84. PubMed ID: 17377063
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The flavonoid quercetin induces hypoxia-inducible factor-1alpha (HIF-1alpha) and inhibits cell proliferation by depleting intracellular iron.
    Triantafyllou A; Liakos P; Tsakalof A; Chachami G; Paraskeva E; Molyvdas PA; Georgatsou E; Simos G; Bonanou S
    Free Radic Res; 2007 Mar; 41(3):342-56. PubMed ID: 17364964
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor.
    Wang M; Kirk JS; Venkataraman S; Domann FE; Zhang HJ; Schafer FQ; Flanagan SW; Weydert CJ; Spitz DR; Buettner GR; Oberley LW
    Oncogene; 2005 Dec; 24(55):8154-66. PubMed ID: 16170370
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A group of novel HIF-1α inhibitors, glyceollins, blocks HIF-1α synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding.
    Lee SH; Jee JG; Bae JS; Liu KH; Lee YM
    J Cell Physiol; 2015 Apr; 230(4):853-62. PubMed ID: 25204544
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1α.
    Shan JZ; Xuan YY; Zhang Q; Huang JJ
    J Zhejiang Univ Sci B; 2016 Sep; 17(9):672-82. PubMed ID: 27604859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression.
    Luwor RB; Lu Y; Li X; Mendelsohn J; Fan Z
    Oncogene; 2005 Jun; 24(27):4433-41. PubMed ID: 15806152
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.
    Chen MC; Lee CF; Huang WH; Chou TC
    Biochem Pharmacol; 2013 May; 85(9):1278-87. PubMed ID: 23416116
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.
    Merighi S; Benini A; Mirandola P; Gessi S; Varani K; Simioni C; Leung E; Maclennan S; Baraldi PG; Borea PA
    Mol Pharmacol; 2007 Aug; 72(2):395-406. PubMed ID: 17488804
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway.
    Tan C; de Noronha RG; Roecker AJ; Pyrzynska B; Khwaja F; Zhang Z; Zhang H; Teng Q; Nicholson AC; Giannakakou P; Zhou W; Olson JJ; Pereira MM; Nicolaou KC; Van Meir EG
    Cancer Res; 2005 Jan; 65(2):605-12. PubMed ID: 15695405
    [TBL] [Abstract][Full Text] [Related]  

  • 14. KNK437, abrogates hypoxia-induced radioresistance by dual targeting of the AKT and HIF-1α survival pathways.
    Oommen D; Prise KM
    Biochem Biophys Res Commun; 2012 May; 421(3):538-43. PubMed ID: 22521642
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The antioxidant quercetin inhibits cellular proliferation via HIF-1-dependent induction of p21WAF.
    Bach A; Bender-Sigel J; Schrenk D; Flügel D; Kietzmann T
    Antioxid Redox Signal; 2010 Aug; 13(4):437-48. PubMed ID: 19958256
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Does endogenous fatty acid metabolism allow cancer cells to sense hypoxia and mediate hypoxic vasodilatation? Characterization of a novel molecular connection between fatty acid synthase (FAS) and hypoxia-inducible factor-1alpha (HIF-1alpha)-related expression of vascular endothelial growth factor (VEGF) in cancer cells overexpressing her-2/neu oncogene.
    Menendez JA; Vellon L; Oza BP; Lupu R
    J Cell Biochem; 2005 Apr; 94(5):857-63. PubMed ID: 15669079
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Hypoxia induced HIF-1 accumulation and VEGF expression in gastric epithelial mucosa cell: involvement of ERK1/2 and PI3K/Akt].
    Liu L; Ning X; Han S; Zhang H; Sun L; Shi Y; Sun S; Guo C; Yin F; Qiao T; Wu K; Fan D
    Mol Biol (Mosk); 2008; 42(3):459-69. PubMed ID: 18702304
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells.
    Cho SY; Lee HJ; Jeong SJ; Lee HJ; Kim HS; Chen CY; Lee EO; Kim SH
    J Pineal Res; 2011 Aug; 51(1):87-93. PubMed ID: 21392092
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cardiac glycosides suppress the maintenance of stemness and malignancy via inhibiting HIF-1α in human glioma stem cells.
    Lee DH; Cheul Oh S; Giles AJ; Jung J; Gilbert MR; Park DM
    Oncotarget; 2017 Jun; 8(25):40233-40245. PubMed ID: 28410215
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hypoxic stress simultaneously stimulates vascular endothelial growth factor via hypoxia-inducible factor-1α and inhibits stromal cell-derived factor-1 in human endometrial stromal cells.
    Tsuzuki T; Okada H; Cho H; Tsuji S; Nishigaki A; Yasuda K; Kanzaki H
    Hum Reprod; 2012 Feb; 27(2):523-30. PubMed ID: 22128293
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.