BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 18661957)

  • 1. Differential enzymatic reductions governing the differential hypoxia-selective cytotoxicities of phenazine 5,10-dioxides.
    Lavaggi ML; Cabrera M; González M; Cerecetto H
    Chem Res Toxicol; 2008 Sep; 21(9):1900-6. PubMed ID: 18661957
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reduction of chromium(VI) to chromium(V) by rat liver cytosolic and microsomal fractions: is DT-diaphorase involved?
    Aiyar J; De Flora S; Wetterhahn KE
    Carcinogenesis; 1992 Jul; 13(7):1159-66. PubMed ID: 1379126
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J; Oleschuk CJ; Guziec F; Guziec L; Fiterman DJ; Monterrosa C; Begleiter A
    Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural modifications on the phenazine N,N'-dioxide-scaffold looking for new selective hypoxic cytotoxins.
    Lavaggi ML; Nieves M; Cabrera M; Olea-Azar C; López de Ceráin A; Monge A; Cerecetto H; González M
    Eur J Med Chem; 2010 Nov; 45(11):5362-9. PubMed ID: 20846761
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reductase-mediated metabolism of motexafin gadolinium (Xcytrin) in rat and human liver subcellular fractions and purified enzyme preparations.
    Mani C; Upadhyay S; Lacy S; Boswell GW; Miles DR
    J Pharm Sci; 2005 Mar; 94(3):559-70. PubMed ID: 15666291
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reductive metabolism of the nitroimidazole-based hypoxia-selective cytotoxin NLCQ-1 (NSC 709257).
    Papadopoulou MV; Ji M; Rao MK; Bloomer WD
    Oncol Res; 2003; 14(1):21-9. PubMed ID: 14552588
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Study of benzo[a]phenazine 7,12-dioxide as selective hypoxic cytotoxin-scaffold. Identification of aerobic-antitumoral activity through DNA fragmentation.
    Lavaggi ML; Cabrera M; Aravena Mde L; Olea-Azar C; López de Ceráin A; Monge A; Pachón G; Cascante M; Bruno AM; Pietrasanta LI; González M; Cerecetto H
    Bioorg Med Chem; 2010 Jun; 18(12):4433-40. PubMed ID: 20471844
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzymology of the reductive bioactivation of SR 4233. A novel benzotriazine di-N-oxide hypoxic cell cytotoxin.
    Walton MI; Workman P
    Biochem Pharmacol; 1990 Jun; 39(11):1735-42. PubMed ID: 2344370
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of trenimon-induced cytotoxicity by DT-diaphorase in isolated rat hepatocytes under aerobic versus hypoxic conditions.
    Silva JM; Rao DN; O'Brien PJ
    Cancer Res; 1992 Jun; 52(11):3015-21. PubMed ID: 1375532
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phenazine 5,10-dioxide derivatives as hypoxic selective cytotoxins: Part II. Structure-activity relationship studies.
    Cerecetto H; González M; Lavaggi ML; Aravena MA; Rigol C; Olea-Azar C; Azqueta A; de Cerain AL; Monge A; Bruno AM
    Med Chem; 2006 Sep; 2(5):511-21. PubMed ID: 17017991
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p-nitrosophenol reduction by liver cytosol from ADH-positive and -negative deermice (Peromyscus maniculatus).
    Dudley BF; Winston GW
    Arch Biochem Biophys; 1995 Feb; 316(2):879-85. PubMed ID: 7532387
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enzymatic and molecular aspects of the antioxidant effect of menadione in hepatic microsomes.
    Tampo Y; Yonaha M
    Arch Biochem Biophys; 1996 Oct; 334(1):163-74. PubMed ID: 8837752
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro biotransformation and investigation of metabolic enzymes possibly responsible for the metabolism of bisdesoxyolaquindox in the liver fractions of rats, chicken, and pigs.
    Liu ZY; Chen DM; Huang LL; Tao YF; Yao M; Yuan ZH
    Toxicology; 2011 Jan; 279(1-3):155-66. PubMed ID: 20955753
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Metabolism of nicousamide in rat and human liver in vitro].
    Sheng L; Hu JP; Chen H; Li Y
    Yao Xue Xue Bao; 2008 Sep; 43(9):912-6. PubMed ID: 19048781
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phenazine 5,10-dioxide derivatives as hypoxic selective cytotoxins.
    Cerecetto H; González M; Lavaggi ML; Azqueta A; López de Cerain A; Monge A
    J Med Chem; 2005 Jan; 48(1):21-3. PubMed ID: 15633996
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Requirement for iron for the production of hydroxyl radicals by rat liver quinone reductase.
    Dicker E; Cederbaum AI
    J Pharmacol Exp Ther; 1993 Sep; 266(3):1282-90. PubMed ID: 7690400
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The metabolism and N-oxide reduction of olaquindox in liver preparations of rats, pigs and chicken.
    Liu ZY; Huang LL; Chen DM; Dai MH; Tao YF; Yuan ZH
    Toxicol Lett; 2010 May; 195(1):51-9. PubMed ID: 20219653
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.
    Keyes SR; Fracasso PM; Heimbrook DC; Rockwell S; Sligar SG; Sartorelli AC
    Cancer Res; 1984 Dec; 44(12 Pt 1):5638-43. PubMed ID: 6437671
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The aliphatic oxidation of salmeterol to alpha-hydroxysalmeterol in human liver microsomes is catalyzed by CYP3A.
    Manchee GR; Eddershaw PJ; Ranshaw LE; Herriott D; Park GR; Bayliss MK; Tarbit MH
    Drug Metab Dispos; 1996 May; 24(5):555-9. PubMed ID: 8723736
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prominent role of DT-diaphorase as a cellular mechanism reducing chromium(VI) and reverting its mutagenicity.
    De Flora S; Morelli A; Basso C; Romano M; Serra D; De Flora A
    Cancer Res; 1985 Jul; 45(7):3188-96. PubMed ID: 4005852
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.