446 related articles for article (PubMed ID: 18664504)
1. Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.
Scamuffa N; Basak A; Lalou C; Wargnier A; Marcinkiewicz J; Siegfried G; Chrétien M; Calvo F; Seidah NG; Khatib AM
Gut; 2008 Nov; 57(11):1573-82. PubMed ID: 18664504
[TBL] [Abstract][Full Text] [Related]
2. Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin.
Guillemot J; Canuel M; Essalmani R; Prat A; Seidah NG
Hepatology; 2013 Jun; 57(6):2514-24. PubMed ID: 23390091
[TBL] [Abstract][Full Text] [Related]
3. Activation and inactivation of the iron hormone hepcidin: Biochemical characterization of prohepcidin cleavage and sequential degradation to N-terminally truncated hepcidin isoforms.
Schranz M; Bakry R; Creus M; Bonn G; Vogel W; Zoller H
Blood Cells Mol Dis; 2009; 43(2):169-79. PubMed ID: 19423366
[TBL] [Abstract][Full Text] [Related]
4. Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7.
Lissitzky JC; Luis J; Munzer JS; Benjannet S; Parat F; Chrétien M; Marvaldi J; Seidah NG
Biochem J; 2000 Feb; 346 Pt 1(Pt 1):133-8. PubMed ID: 10657249
[TBL] [Abstract][Full Text] [Related]
5. Engineering of α1-antitrypsin variants with improved specificity for the proprotein convertase furin using site-directed random mutagenesis.
Hada K; Isshiki K; Matsuda S; Yuasa K; Tsuji A
Protein Eng Des Sel; 2013 Feb; 26(2):123-31. PubMed ID: 23155057
[TBL] [Abstract][Full Text] [Related]
6. Subtilisin-like proprotein convertase paired basic amino acid-cleaving enzyme 4 is required for chondrogenic differentiation in ATDC5 cells.
Yuasa K; Futamatsu G; Kawano T; Muroshita M; Kageyama Y; Taichi H; Ishikawa H; Nagahama M; Matsuda Y; Tsuji A
FEBS J; 2012 Nov; 279(21):3997-4009. PubMed ID: 22925071
[TBL] [Abstract][Full Text] [Related]
7. Thrombin activation of protein C requires prior processing by a liver proprotein convertase.
Essalmani R; Susan-Resiga D; Guillemot J; Kim W; Sachan V; Awan Z; Chamberland A; Asselin MC; Ly K; Desjardins R; Day R; Prat A; Seidah NG
J Biol Chem; 2017 Jun; 292(25):10564-10573. PubMed ID: 28468828
[TBL] [Abstract][Full Text] [Related]
8. The proprotein convertases furin and PACE4 play a significant role in tumor progression.
Bassi DE; Mahloogi H; Klein-Szanto AJ
Mol Carcinog; 2000 Jun; 28(2):63-9. PubMed ID: 10900462
[TBL] [Abstract][Full Text] [Related]
9. Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage.
Bergeron E; Basak A; Decroly E; Seidah NG
Biochem J; 2003 Jul; 373(Pt 2):475-84. PubMed ID: 12691605
[TBL] [Abstract][Full Text] [Related]
10. Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells' malignant phenotypes: role of tissue inhibitors of metalloproteinase-1.
Lapierre M; Siegfried G; Scamuffa N; Bontemps Y; Calvo F; Seidah NG; Khatib AM
Cancer Res; 2007 Oct; 67(19):9030-4. PubMed ID: 17909005
[TBL] [Abstract][Full Text] [Related]
11. Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder.
Kim W; Zekas E; Lodge R; Susan-Resiga D; Marcinkiewicz E; Essalmani R; Mihara K; Ramachandran R; Asahchop E; Gelman B; Cohen ÉA; Power C; Hollenberg MD; Seidah NG
Mol Cell Biol; 2015 Nov; 35(21):3684-700. PubMed ID: 26283733
[TBL] [Abstract][Full Text] [Related]
12. The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates.
Mayer G; Hamelin J; Asselin MC; Pasquato A; Marcinkiewicz E; Tang M; Tabibzadeh S; Seidah NG
J Biol Chem; 2008 Jan; 283(4):2373-84. PubMed ID: 18039650
[TBL] [Abstract][Full Text] [Related]
13. Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases.
Siegfried G; Basak A; Prichett-Pejic W; Scamuffa N; Ma L; Benjannet S; Veinot JP; Calvo F; Seidah N; Khatib AM
Oncogene; 2005 Oct; 24(46):6925-35. PubMed ID: 16007151
[TBL] [Abstract][Full Text] [Related]
14. Pro-protein convertases (PCs) other than PC6 are not tightly regulated for implantation in the human endometrium.
Freyer C; Kilpatrick LM; Salamonsen LA; Nie G
Reproduction; 2007 Jun; 133(6):1189-97. PubMed ID: 17636173
[TBL] [Abstract][Full Text] [Related]
15.
Al Rifai O; Susan-Resiga D; Essalmani R; Creemers JWM; Seidah NG; Ferron M
Front Endocrinol (Lausanne); 2021; 12():690681. PubMed ID: 34149625
[TBL] [Abstract][Full Text] [Related]
16. Comparative study of the binding pockets of mammalian proprotein convertases and its implications for the design of specific small molecule inhibitors.
Tian S; Jianhua W
Int J Biol Sci; 2010 Feb; 6(1):89-95. PubMed ID: 20151049
[TBL] [Abstract][Full Text] [Related]
17. Human lactase-phlorizin hydrolase is not processed by furin, PC1/PC3, PC2, PACE4 and PC5/PC6A of the family of subtilisin-like proprotein processing proteases.
Wüthrich M; Creemers JW; van de Ven WJ; Sterchi EE
Biochim Biophys Acta; 1996 May; 1311(3):199-203. PubMed ID: 8664347
[TBL] [Abstract][Full Text] [Related]
18. The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis.
Siegfried G; Basak A; Cromlish JA; Benjannet S; Marcinkiewicz J; Chrétien M; Seidah NG; Khatib AM
J Clin Invest; 2003 Jun; 111(11):1723-32. PubMed ID: 12782675
[TBL] [Abstract][Full Text] [Related]
19. Development of selectivity of alpha1-antitrypsin variant by mutagenesis in its reactive site loop against proprotein convertase. A crucial role of the P4 arginine in PACE4 inhibition.
Tsuji A; Ikoma T; Hashimoto E; Matsuda Y
Protein Eng; 2002 Feb; 15(2):123-30. PubMed ID: 11917148
[TBL] [Abstract][Full Text] [Related]
20. Increased proteolytic processing of protein tyrosine phosphatase mu in confluent vascular endothelial cells: the role of PC5, a member of the subtilisin family.
Campan M; Yoshizumi M; Seidah NG; Lee ME; Bianchi C; Haber E
Biochemistry; 1996 Mar; 35(12):3797-802. PubMed ID: 8620001
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
