313 related articles for article (PubMed ID: 18665319)
1. Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice.
Gutknecht L; Waider J; Kraft S; Kriegebaum C; Holtmann B; Reif A; Schmitt A; Lesch KP
J Neural Transm (Vienna); 2008 Aug; 115(8):1127-32. PubMed ID: 18665319
[TBL] [Abstract][Full Text] [Related]
2. Brain-specific conditional and time-specific inducible Tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life.
Kriegebaum C; Song NN; Gutknecht L; Huang Y; Schmitt A; Reif A; Ding YQ; Lesch KP
Neurochem Int; 2010 Nov; 57(5):512-7. PubMed ID: 20599453
[TBL] [Abstract][Full Text] [Related]
3. Impacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification.
Gutknecht L; Araragi N; Merker S; Waider J; Sommerlandt FM; Mlinar B; Baccini G; Mayer U; Proft F; Hamon M; Schmitt AG; Corradetti R; Lanfumey L; Lesch KP
PLoS One; 2012; 7(8):e43157. PubMed ID: 22912815
[TBL] [Abstract][Full Text] [Related]
4. Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels.
Nakamura K; Sugawara Y; Sawabe K; Ohashi A; Tsurui H; Xiu Y; Ohtsuji M; Lin QS; Nishimura H; Hasegawa H; Hirose S
J Neurosci; 2006 Jan; 26(2):530-4. PubMed ID: 16407550
[TBL] [Abstract][Full Text] [Related]
5. Robust and tissue-specific expression of TPH2 versus TPH1 in rat raphe and pineal gland.
Patel PD; Pontrello C; Burke S
Biol Psychiatry; 2004 Feb; 55(4):428-33. PubMed ID: 14960297
[TBL] [Abstract][Full Text] [Related]
6. Deficiency of Serotonin in Raphe Neurons and Altered Behavioral Responses in Tryptophan Hydroxylase 2-Knockout Medaka (Oryzias latipes).
Ansai S; Hosokawa H; Maegawa S; Naruse K; Washio Y; Sato K; Kinoshita M
Zebrafish; 2017 Dec; 14(6):495-507. PubMed ID: 28933662
[TBL] [Abstract][Full Text] [Related]
7. Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice.
Lieb MW; Weidner M; Arnold MR; Loupy KM; Nguyen KT; Hassell JE; Schnabel KS; Kern R; Day HEW; Lesch KP; Waider J; Lowry CA
Behav Brain Res; 2019 Nov; 373():112086. PubMed ID: 31319134
[TBL] [Abstract][Full Text] [Related]
8. Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice.
Waider J; Popp S; Lange MD; Kern R; Kolter JF; Kobler J; Donner NC; Lowe KR; Malzbender JH; Brazell CJ; Arnold MR; Aboagye B; Schmitt-Böhrer A; Lowry CA; Pape HC; Lesch KP
Transl Psychiatry; 2017 Oct; 7(10):e1246. PubMed ID: 28972592
[TBL] [Abstract][Full Text] [Related]
9. Neuronal tryptophan hydroxylase expression in BALB/cJ and C57Bl/6J mice.
Bach H; Arango V; Huang YY; Leong S; Mann JJ; Underwood MD
J Neurochem; 2011 Sep; 118(6):1067-74. PubMed ID: 21740442
[TBL] [Abstract][Full Text] [Related]
10. Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.
Gutknecht L; Kriegebaum C; Waider J; Schmitt A; Lesch KP
Eur Neuropsychopharmacol; 2009 Apr; 19(4):266-82. PubMed ID: 19181488
[TBL] [Abstract][Full Text] [Related]
11. Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice.
Jacobsen JP; Siesser WB; Sachs BD; Peterson S; Cools MJ; Setola V; Folgering JH; Flik G; Caron MG
Mol Psychiatry; 2012 Jul; 17(7):694-704. PubMed ID: 21537332
[TBL] [Abstract][Full Text] [Related]
12. Endogenous Deficiency of Brain-Derived Neurotrophic Factor Induces the Downregulation of Tryptophan Hydroxylase-2 Expression in Raphe Nuclei of Rapid Ejaculator Rats.
Huang Y; Peng D; Geng H; Dai Y; Jiang H; Zhang X
J Sex Med; 2021 Sep; 18(9):1491-1499. PubMed ID: 34384732
[TBL] [Abstract][Full Text] [Related]
13. Altered expression of neuronal tryptophan hydroxylase-2 mRNA in the dorsal and median raphe nuclei of three genetically modified mouse models relevant to depression and anxiety.
Jahanshahi A; Le Maitre E; Temel Y; Lanfumey L; Hamon M; Lesch KP; Tordera RM; Del Río J; Aso E; Maldonado R; Hökfelt T; Steinbusch HW
J Chem Neuroanat; 2011 Jul; 41(4):227-33. PubMed ID: 21704153
[TBL] [Abstract][Full Text] [Related]
14. Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin.
Pelosi B; Pratelli M; Migliarini S; Pacini G; Pasqualetti M
PLoS One; 2015; 10(8):e0136422. PubMed ID: 26291320
[TBL] [Abstract][Full Text] [Related]
15. Lithium modulates tryptophan hydroxylase 2 gene expression and serotonin release in primary cultures of serotonergic raphe neurons.
Scheuch K; Höltje M; Budde H; Lautenschlager M; Heinz A; Ahnert-Hilger G; Priller J
Brain Res; 2010 Jan; 1307():14-21. PubMed ID: 19840776
[TBL] [Abstract][Full Text] [Related]
16. Targeted Manipulation of Brain Serotonin: RNAi-Mediated Knockdown of Tryptophan Hydroxylase 2 in Rats.
Matthes S; Mosienko V; Popova E; Rivalan M; Bader M; Alenina N
ACS Chem Neurosci; 2019 Jul; 10(7):3207-3217. PubMed ID: 30977636
[TBL] [Abstract][Full Text] [Related]
17. Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice.
Gutknecht L; Popp S; Waider J; Sommerlandt FM; Göppner C; Post A; Reif A; van den Hove D; Strekalova T; Schmitt A; Colaςo MB; Sommer C; Palme R; Lesch KP
Psychopharmacology (Berl); 2015 Jul; 232(14):2429-41. PubMed ID: 25716307
[TBL] [Abstract][Full Text] [Related]
18. Serotonin (5-HT) in the regulation of depression-related emotionality: insight from 5-HT transporter and tryptophan hydroxylase-2 knockout mouse models.
Araragi N; Lesch KP
Curr Drug Targets; 2013 May; 14(5):549-70. PubMed ID: 23547810
[TBL] [Abstract][Full Text] [Related]
19. Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.
Savelieva KV; Zhao S; Pogorelov VM; Rajan I; Yang Q; Cullinan E; Lanthorn TH
PLoS One; 2008; 3(10):e3301. PubMed ID: 18923670
[TBL] [Abstract][Full Text] [Related]
20. Chronic central serotonin depletion attenuates ventilation and body temperature in young but not adult Tph2 knockout rats.
Kaplan K; Echert AE; Massat B; Puissant MM; Palygin O; Geurts AM; Hodges MR
J Appl Physiol (1985); 2016 May; 120(9):1070-81. PubMed ID: 26869713
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]