253 related articles for article (PubMed ID: 18666033)
1. Signaling cascades as drug targets in model and pathogenic fungi.
Bastidas RJ; Reedy JL; Morales-Johansson H; Heitman J; Cardenas ME
Curr Opin Investig Drugs; 2008 Aug; 9(8):856-64. PubMed ID: 18666033
[TBL] [Abstract][Full Text] [Related]
2. Heat shock protein inhibitors for the treatment of fungal infections.
Wirk B
Recent Pat Antiinfect Drug Discov; 2011 Jan; 6(1):38-44. PubMed ID: 21192778
[TBL] [Abstract][Full Text] [Related]
3. Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach.
Juvvadi PR; Lee SC; Heitman J; Steinbach WJ
Virulence; 2017 Feb; 8(2):186-197. PubMed ID: 27325145
[TBL] [Abstract][Full Text] [Related]
4. Signal-transduction cascades as targets for therapeutic intervention by natural products.
Cardenas ME; Sanfridson A; Cutler NS; Heitman J
Trends Biotechnol; 1998 Oct; 16(10):427-33. PubMed ID: 9807840
[TBL] [Abstract][Full Text] [Related]
5. Nonapoptotic death of Saccharomyces cerevisiae cells that is stimulated by Hsp90 and inhibited by calcineurin and Cmk2 in response to endoplasmic reticulum stresses.
Dudgeon DD; Zhang N; Ositelu OO; Kim H; Cunningham KW
Eukaryot Cell; 2008 Dec; 7(12):2037-51. PubMed ID: 18806210
[TBL] [Abstract][Full Text] [Related]
6. Dual action antifungal small molecule modulates multidrug efflux and TOR signaling.
Shekhar-Guturja T; Gunaherath GM; Wijeratne EM; Lambert JP; Averette AF; Lee SC; Kim T; Bahn YS; Tripodi F; Ammar R; Döhl K; Niewola-Staszkowska K; Schmitt L; Loewith RJ; Roth FP; Sanglard D; Andes D; Nislow C; Coccetti P; Gingras AC; Heitman J; Gunatilaka AA; Cowen LE
Nat Chem Biol; 2016 Oct; 12(10):867-75. PubMed ID: 27571477
[TBL] [Abstract][Full Text] [Related]
7. Echinocandin resistance in human pathogenic fungi.
Munro CA
Expert Rev Anti Infect Ther; 2012 Feb; 10(2):115-6. PubMed ID: 22339184
[No Abstract] [Full Text] [Related]
8. A novel calcineurin-independent activity of cyclosporin A in Saccharomyces cerevisiae.
Singh-Babak SD; Shekhar T; Smith AM; Giaever G; Nislow C; Cowen LE
Mol Biosyst; 2012 Oct; 8(10):2575-84. PubMed ID: 22751784
[TBL] [Abstract][Full Text] [Related]
9. Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species.
Lamoth F; Alexander BD; Juvvadi PR; Steinbach WJ
J Antimicrob Chemother; 2015 May; 70(5):1408-11. PubMed ID: 25558076
[TBL] [Abstract][Full Text] [Related]
10. Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans.
Arndt C; Cruz MC; Cardenas ME; Heitman J
Microbiology (Reading); 1999 Aug; 145 ( Pt 8)():1989-2000. PubMed ID: 10463165
[TBL] [Abstract][Full Text] [Related]
11. Metabolic control of antifungal drug resistance.
Robbins N; Collins C; Morhayim J; Cowen LE
Fungal Genet Biol; 2010 Feb; 47(2):81-93. PubMed ID: 19595784
[TBL] [Abstract][Full Text] [Related]
12. Structure-guided approaches to targeting stress responses in human fungal pathogens.
LeBlanc EV; Polvi EJ; Veri AO; Privé GG; Cowen LE
J Biol Chem; 2020 Oct; 295(42):14458-14472. PubMed ID: 32796038
[TBL] [Abstract][Full Text] [Related]
13. Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans.
Del Poeta M; Cruz MC; Cardenas ME; Perfect JR; Heitman J
Antimicrob Agents Chemother; 2000 Mar; 44(3):739-46. PubMed ID: 10681348
[TBL] [Abstract][Full Text] [Related]
14. Genetic architecture of Hsp90-dependent drug resistance.
Cowen LE; Carpenter AE; Matangkasombut O; Fink GR; Lindquist S
Eukaryot Cell; 2006 Dec; 5(12):2184-8. PubMed ID: 17056742
[TBL] [Abstract][Full Text] [Related]
15. Targeting the fungal calcium-calcineurin signaling network in overcoming drug resistance.
Li X; Sun S
Future Med Chem; 2016 Aug; 8(12):1379-81. PubMed ID: 27463738
[No Abstract] [Full Text] [Related]
16. Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease.
Cowen LE; Singh SD; Köhler JR; Collins C; Zaas AK; Schell WA; Aziz H; Mylonakis E; Perfect JR; Whitesell L; Lindquist S
Proc Natl Acad Sci U S A; 2009 Feb; 106(8):2818-23. PubMed ID: 19196973
[TBL] [Abstract][Full Text] [Related]
17. Heat shock protein 90 (Hsp90): A novel antifungal target against Aspergillus fumigatus.
Lamoth F; Juvvadi PR; Steinbach WJ
Crit Rev Microbiol; 2016; 42(2):310-21. PubMed ID: 25243616
[TBL] [Abstract][Full Text] [Related]
18. Roles of the Hsp90-Calcineurin Pathway in the Antifungal Activity of Honokiol.
Liao K; Sun L
J Microbiol Biotechnol; 2018 Jul; 28(7):1086-1093. PubMed ID: 29913547
[TBL] [Abstract][Full Text] [Related]
19. Teaching old drugs new tricks: reincarnating immunosuppressants as antifungal drugs.
Blankenship JR; Steinbach WJ; Perfect JR; Heitman J
Curr Opin Investig Drugs; 2003 Feb; 4(2):192-9. PubMed ID: 12669381
[TBL] [Abstract][Full Text] [Related]
20. Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections.
Steinbach WJ; Reedy JL; Cramer RA; Perfect JR; Heitman J
Nat Rev Microbiol; 2007 Jun; 5(6):418-30. PubMed ID: 17505522
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
