BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

499 related articles for article (PubMed ID: 18667150)

  • 1. Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks.
    Kuchibhotla KV; Goldman ST; Lattarulo CR; Wu HY; Hyman BT; Bacskai BJ
    Neuron; 2008 Jul; 59(2):214-25. PubMed ID: 18667150
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease.
    Knowles RB; Wyart C; Buldyrev SV; Cruz L; Urbanc B; Hasselmo ME; Stanley HE; Hyman BT
    Proc Natl Acad Sci U S A; 1999 Apr; 96(9):5274-9. PubMed ID: 10220456
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Immunotherapy with Aducanumab Restores Calcium Homeostasis in Tg2576 Mice.
    Kastanenka KV; Bussiere T; Shakerdge N; Qian F; Weinreb PH; Rhodes K; Bacskai BJ
    J Neurosci; 2016 Dec; 36(50):12549-12558. PubMed ID: 27810931
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel botanical drug DA-9803 prevents deficits in Alzheimer's mouse models.
    Pagnier GJ; Kastanenka KV; Sohn M; Choi S; Choi SH; Soh H; Bacskai BJ
    Alzheimers Res Ther; 2018 Jan; 10(1):11. PubMed ID: 29378621
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease.
    Collins JM; King AE; Woodhouse A; Kirkcaldie MT; Vickers JC
    Exp Neurol; 2015 May; 267():219-29. PubMed ID: 25747037
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease.
    Sadleir KR; Kandalepas PC; Buggia-Prévot V; Nicholson DA; Thinakaran G; Vassar R
    Acta Neuropathol; 2016 Aug; 132(2):235-256. PubMed ID: 26993139
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease.
    Meyer-Luehmann M; Spires-Jones TL; Prada C; Garcia-Alloza M; de Calignon A; Rozkalne A; Koenigsknecht-Talboo J; Holtzman DM; Bacskai BJ; Hyman BT
    Nature; 2008 Feb; 451(7179):720-4. PubMed ID: 18256671
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice.
    Kuchibhotla KV; Lattarulo CR; Hyman BT; Bacskai BJ
    Science; 2009 Feb; 323(5918):1211-5. PubMed ID: 19251629
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models.
    Hsia AY; Masliah E; McConlogue L; Yu GQ; Tatsuno G; Hu K; Kholodenko D; Malenka RC; Nicoll RA; Mucke L
    Proc Natl Acad Sci U S A; 1999 Mar; 96(6):3228-33. PubMed ID: 10077666
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cerebellar amyloid-β plaques: disturbed cortical circuitry in AβPP/PS1 transgenic mice as a model of familial Alzheimer's disease.
    Lomoio S; López-González I; Aso E; Carmona M; Torrejón-Escribano B; Scherini E; Ferrer I
    J Alzheimers Dis; 2012; 31(2):285-300. PubMed ID: 22561329
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease.
    Sosna J; Philipp S; Albay R; Reyes-Ruiz JM; Baglietto-Vargas D; LaFerla FM; Glabe CG
    Mol Neurodegener; 2018 Mar; 13(1):11. PubMed ID: 29490706
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Calsyntenin-3 C-terminal fragment accumulates in dystrophic neurites surrounding aβ plaques in tg2576 mouse and Alzheimer disease brains: its neurotoxic role in mediating dystrophic neurite formation.
    Uchida Y; Gomi F; Murayama S; Takahashi H
    Am J Pathol; 2013 May; 182(5):1718-26. PubMed ID: 23499467
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease.
    Jackson RJ; Rudinskiy N; Herrmann AG; Croft S; Kim JM; Petrova V; Ramos-Rodriguez JJ; Pitstick R; Wegmann S; Garcia-Alloza M; Carlson GA; Hyman BT; Spires-Jones TL
    Eur J Neurosci; 2016 Dec; 44(12):3056-3066. PubMed ID: 27748574
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Potential involvement of abnormal increased SUMO-1 in modulation of the formation of Alzheimer's disease senile plaques and neuritic dystrophy in APP/PS1 transgenic mice].
    Zhao XY; Wang DD; Shan Y; Zhu CQ
    Sheng Li Xue Bao; 2013 Jun; 65(3):253-62. PubMed ID: 23788181
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Alzheimer disease: cellular and molecular aspects].
    Octave JN
    Bull Mem Acad R Med Belg; 2005; 160(10-12):445-9; discussion 450-1. PubMed ID: 16768248
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.
    Yamamoto M; Kiyota T; Horiba M; Buescher JL; Walsh SM; Gendelman HE; Ikezu T
    Am J Pathol; 2007 Feb; 170(2):680-92. PubMed ID: 17255335
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.
    Oakley H; Cole SL; Logan S; Maus E; Shao P; Craft J; Guillozet-Bongaarts A; Ohno M; Disterhoft J; Van Eldik L; Berry R; Vassar R
    J Neurosci; 2006 Oct; 26(40):10129-40. PubMed ID: 17021169
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An early dysregulation of FAK and MEK/ERK signaling pathways precedes the β-amyloid deposition in the olfactory bulb of APP/PS1 mouse model of Alzheimer's disease.
    Lachén-Montes M; González-Morales A; de Morentin XM; Pérez-Valderrama E; Ausín K; Zelaya MV; Serna A; Aso E; Ferrer I; Fernández-Irigoyen J; Santamaría E
    J Proteomics; 2016 Oct; 148():149-58. PubMed ID: 27498392
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.
    Sebastian Monasor L; Müller SA; Colombo AV; Tanrioever G; König J; Roth S; Liesz A; Berghofer A; Piechotta A; Prestel M; Saito T; Saido TC; Herms J; Willem M; Haass C; Lichtenthaler SF; Tahirovic S
    Elife; 2020 Jun; 9():. PubMed ID: 32510331
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model.
    Karuppagounder SS; Xu H; Shi Q; Chen LH; Pedrini S; Pechman D; Baker H; Beal MF; Gandy SE; Gibson GE
    Neurobiol Aging; 2009 Oct; 30(10):1587-600. PubMed ID: 18406011
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.