BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 18667782)

  • 1. A new post-PKS modification process in the carbamoyltransferase gene inactivation strain of Streptomyces hygroscopicus 17997.
    Li Y; He W; Wang Y; Wang Y; Shao R
    J Antibiot (Tokyo); 2008 Jun; 61(6):347-55. PubMed ID: 18667782
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivation of the carbamoyltransferase gene refines post-polyketide synthase modification steps in the biosynthesis of the antitumor agent geldanamycin.
    Hong YS; Lee D; Kim W; Jeong JK; Kim CG; Sohng JK; Lee JH; Paik SG; Lee JJ
    J Am Chem Soc; 2004 Sep; 126(36):11142-3. PubMed ID: 15355082
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inactivation of putative PKS genes can double geldanamycin yield in Streptomyces hygroscopicus 17997.
    Li YH; Li M; He WQ; Wang YG; Shao RG
    Genet Mol Res; 2013 Jun; 12(2):2076-85. PubMed ID: 23913387
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.
    Shin JC; Na Z; Lee DH; Kim WC; Lee K; Shen YM; Paik SG; Hong YS; Lee JJ
    J Microbiol Biotechnol; 2008 Jun; 18(6):1101-8. PubMed ID: 18600054
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rational biosynthetic engineering for optimization of geldanamycin analogues.
    Kim W; Lee D; Hong SS; Na Z; Shin JC; Roh SH; Wu CZ; Choi O; Lee K; Shen YM; Paik SG; Lee JJ; Hong YS
    Chembiochem; 2009 May; 10(7):1243-51. PubMed ID: 19308924
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Roles of geldanamycin biosynthetic genes in Streptomyces hygroscopicus 17997].
    He W; Liu Y; Sun G; Wang Y
    Sheng Wu Gong Cheng Xue Bao; 2008 Jul; 24(7):1133-9. PubMed ID: 18837385
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Establishment of gene transduction system in geldanamycin producer - Streptomyces hygroscopicus 17997 and its application for gene disruption experiment].
    Gao HY; Wang YG; Gao QJ; Shang GD; Sun GZ; Yang Y
    Sheng Wu Gong Cheng Xue Bao; 2003 Jul; 19(4):407-11. PubMed ID: 15969055
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997.
    He W; Lei J; Liu Y; Wang Y
    Arch Microbiol; 2008 May; 189(5):501-10. PubMed ID: 18214443
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Cloning and analysis of geldanamycin partial biosynthetic gene cluster of Streptomyces hygroscopicus 17997].
    He WQ; Wang YG
    Sheng Wu Gong Cheng Xue Bao; 2006 Nov; 22(6):902-6. PubMed ID: 17168310
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 7-O-descarbamoyl-7-hydroxygeldanamycin, a minor component from the gdmN disruption mutant of Streptomyces hygroscopicus 17997.
    Ni S; Wu L; Wang H; Wang Y; He W; Li Y; Jia C; Li S; Wang Y
    J Antibiot (Tokyo); 2010 Oct; 63(10):623-5. PubMed ID: 20683449
    [No Abstract]   [Full Text] [Related]  

  • 11. Production of 8-demethylgeldanamycin and 4,5-epoxy-8-demethylgeldanamycin from a recombinant strain of Streptomyces hygroscopicus.
    Buchanan GO; Regentin R; Piagentini M; Rascher A; McDaniel R; Galazzo JL; Licari PJ
    J Nat Prod; 2005 Apr; 68(4):607-10. PubMed ID: 15844961
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel 4,5-dihydro-thiazinogeldanamycin in a gdmP mutant strain of Streptomyces hygroscopicus 17997.
    Lin L; Ni S; Wu L; Wang Y; Wang Y; Tao P; He W; Wang X
    Biosci Biotechnol Biochem; 2011; 75(10):2042-5. PubMed ID: 21979086
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus.
    Wu CZ; Moon AN; Jang JH; Lee D; Kang SY; Park JT; Ahn JS; Hwang BY; Kim YH; Lee HS; Hong YS
    J Antibiot (Tokyo); 2011 Jun; 64(6):461-3. PubMed ID: 21448187
    [No Abstract]   [Full Text] [Related]  

  • 14. Thiazinogeldanamycin, a new geldanamycin derivative produced by Streptomyces hygroscopicus 17997.
    Ni S; Wu L; Wang H; Gan M; Wang Y; He W; Wang Y
    J Microbiol Biotechnol; 2011 Jun; 21(6):599-603. PubMed ID: 21715966
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The missing C-17 O-methyltransferase in geldanamycin biosynthesis.
    Yin M; Lu T; Zhao LX; Chen Y; Huang SX; Lohman JR; Xu LH; Jiang CL; Shen B
    Org Lett; 2011 Jul; 13(14):3726-9. PubMed ID: 21682254
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of 4,5-dihydro-4-hydroxygeldanamycins as shunt products of geldanamycin biosynthesis.
    Li T; Ni S; Jia C; Wang H; Sun G; Wu L; Gan M; Shan G; He W; Lin L; Zhou H; Wang Y
    J Nat Prod; 2012 Aug; 75(8):1480-4. PubMed ID: 22849774
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New, highly active nonbenzoquinone geldanamycin derivatives by using mutasynthesis.
    Eichner S; Floss HG; Sasse F; Kirschning A
    Chembiochem; 2009 Jul; 10(11):1801-5. PubMed ID: 19554593
    [No Abstract]   [Full Text] [Related]  

  • 18. 19-[(1'S,4'R)-4'-Hydroxy-1'-methoxy-2'-oxopentyl]geldanamycin, a natural geldanamycin analogue from Streptomyces hygroscopicus 17997.
    Li S; Ni S; Wu L; Li L; Jiang B; Wang H; Sun G; Gan M; Li J; He W; Lin L; Wang Y; Bai S; Si S
    J Nat Prod; 2013 May; 76(5):969-73. PubMed ID: 23656556
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.
    Seo JW; Ma M; Kwong T; Ju J; Lim SK; Jiang H; Lohman JR; Yang C; Cleveland J; Zazopoulos E; Farnet CM; Shen B
    Biochemistry; 2014 Dec; 53(49):7854-65. PubMed ID: 25405956
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of 6-demethoxy-6-methylgeldanamycin and its implication of geldanamycin biosynthesis.
    Ni S; Jiang B; Wu L; Wang Y; Zhou H; He W; Wang H; Zhu J; Li S; Li T; Zhang K
    J Antibiot (Tokyo); 2014 Feb; 67(2):183-5. PubMed ID: 24105607
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 12.