291 related articles for article (PubMed ID: 18675375)
1. Tryptophan synthase, an allosteric molecular factory.
Barends TR; Dunn MF; Schlichting I
Curr Opin Chem Biol; 2008 Oct; 12(5):593-600. PubMed ID: 18675375
[TBL] [Abstract][Full Text] [Related]
2. Allosteric regulation of substrate channeling in tryptophan synthase: modulation of the L-serine reaction in stage I of the beta-reaction by alpha-site ligands.
Ngo H; Kimmich N; Harris R; Niks D; Blumenstein L; Kulik V; Barends TR; Schlichting I; Dunn MF
Biochemistry; 2007 Jul; 46(26):7740-53. PubMed ID: 17559232
[TBL] [Abstract][Full Text] [Related]
3. The reaction of indole with the aminoacrylate intermediate of Salmonella typhimurium tryptophan synthase: observation of a primary kinetic isotope effect with 3-[(2)H]indole.
Cash MT; Miles EW; Phillips RS
Arch Biochem Biophys; 2004 Dec; 432(2):233-43. PubMed ID: 15542062
[TBL] [Abstract][Full Text] [Related]
4. Cooperative fluctuations and subunit communication in tryptophan synthase.
Bahar I; Jernigan RL
Biochemistry; 1999 Mar; 38(12):3478-90. PubMed ID: 10090734
[TBL] [Abstract][Full Text] [Related]
5. Tryptophan synthase: the workings of a channeling nanomachine.
Dunn MF; Niks D; Ngo H; Barends TR; Schlichting I
Trends Biochem Sci; 2008 Jun; 33(6):254-64. PubMed ID: 18486479
[TBL] [Abstract][Full Text] [Related]
6. Allosteric regulation of tryptophan synthase channeling: the internal aldimine probed by trans-3-indole-3'-acrylate binding.
Casino P; Niks D; Ngo H; Pan P; Brzovic P; Blumenstein L; Barends TR; Schlichting I; Dunn MF
Biochemistry; 2007 Jul; 46(26):7728-39. PubMed ID: 17559231
[TBL] [Abstract][Full Text] [Related]
7. On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
Kulik V; Hartmann E; Weyand M; Frey M; Gierl A; Niks D; Dunn MF; Schlichting I
J Mol Biol; 2005 Sep; 352(3):608-20. PubMed ID: 16120446
[TBL] [Abstract][Full Text] [Related]
8. Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Rhee S; Parris KD; Hyde CC; Ahmed SA; Miles EW; Davies DR
Biochemistry; 1997 Jun; 36(25):7664-80. PubMed ID: 9201907
[TBL] [Abstract][Full Text] [Related]
9. Allosteric regulation of tryptophan synthase: effects of pH, temperature, and alpha-subunit ligands on the equilibrium distribution of pyridoxal 5'-phosphate-L-serine intermediates.
Peracchi A; Bettati S; Mozzarelli A; Rossi GL; Miles EW; Dunn MF
Biochemistry; 1996 Feb; 35(6):1872-80. PubMed ID: 8639669
[TBL] [Abstract][Full Text] [Related]
10. Loop closure and intersubunit communication in tryptophan synthase.
Schneider TR; Gerhardt E; Lee M; Liang PH; Anderson KS; Schlichting I
Biochemistry; 1998 Apr; 37(16):5394-406. PubMed ID: 9548921
[TBL] [Abstract][Full Text] [Related]
11. Allosteric regulation of substrate channeling and catalysis in the tryptophan synthase bienzyme complex.
Dunn MF
Arch Biochem Biophys; 2012 Mar; 519(2):154-66. PubMed ID: 22310642
[TBL] [Abstract][Full Text] [Related]
12. beta-Site covalent reactions trigger transitions between open and closed conformations of the tryptophan synthase bienzyme complex.
Pan P; Dunn MF
Biochemistry; 1996 Apr; 35(15):5002-13. PubMed ID: 8664293
[TBL] [Abstract][Full Text] [Related]
13. Control of ionizable residues in the catalytic mechanism of tryptophan synthase from Salmonella typhimurium.
Raboni S; Mozzarelli A; Cook PF
Biochemistry; 2007 Nov; 46(45):13223-34. PubMed ID: 17927213
[TBL] [Abstract][Full Text] [Related]
14. Cryocrystallography and microspectrophotometry of a mutant (alpha D60N) tryptophan synthase alpha 2 beta 2 complex reveals allosteric roles of alpha Asp60.
Rhee S; Miles EW; Mozzarelli A; Davies DR
Biochemistry; 1998 Jul; 37(30):10653-9. PubMed ID: 9692955
[TBL] [Abstract][Full Text] [Related]
15. Large conformational changes in the Escherichia coli tryptophan synthase beta(2) subunit upon pyridoxal 5'-phosphate binding.
Nishio K; Ogasahara K; Morimoto Y; Tsukihara T; Lee SJ; Yutani K
FEBS J; 2010 May; 277(9):2157-70. PubMed ID: 20370823
[TBL] [Abstract][Full Text] [Related]
16. Allosteric communication in the tryptophan synthase bienzyme complex: roles of the beta-subunit aspartate 305-arginine 141 salt bridge.
Ferrari D; Niks D; Yang LH; Miles EW; Dunn MF
Biochemistry; 2003 Jul; 42(25):7807-18. PubMed ID: 12820890
[TBL] [Abstract][Full Text] [Related]
17. BetaQ114N and betaT110V mutations reveal a critically important role of the substrate alpha-carboxylate site in the reaction specificity of tryptophan synthase.
Blumenstein L; Domratcheva T; Niks D; Ngo H; Seidel R; Dunn MF; Schlichting I
Biochemistry; 2007 Dec; 46(49):14100-16. PubMed ID: 18004874
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and characterization of allosteric probes of substrate channeling in the tryptophan synthase bienzyme complex.
Ngo H; Harris R; Kimmich N; Casino P; Niks D; Blumenstein L; Barends TR; Kulik V; Weyand M; Schlichting I; Dunn MF
Biochemistry; 2007 Jul; 46(26):7713-27. PubMed ID: 17559195
[TBL] [Abstract][Full Text] [Related]
19. Mechanisms of monovalent cation action in enzyme catalysis: the first stage of the tryptophan synthase beta-reaction.
Woehl E; Dunn MF
Biochemistry; 1999 Jun; 38(22):7118-30. PubMed ID: 10353822
[TBL] [Abstract][Full Text] [Related]
20. Synergistic regulation and ligand-induced conformational changes of tryptophan synthase.
Fatmi MQ; Ai R; Chang CE
Biochemistry; 2009 Oct; 48(41):9921-31. PubMed ID: 19764814
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]