BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 18677410)

  • 21. Aberrant expression of RasGRP1 cooperates with gain-of-function NOTCH1 mutations in T-cell leukemogenesis.
    Oki T; Kitaura J; Watanabe-Okochi N; Nishimura K; Maehara A; Uchida T; Komeno Y; Nakahara F; Harada Y; Sonoki T; Harada H; Kitamura T
    Leukemia; 2012 May; 26(5):1038-45. PubMed ID: 22116551
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.
    Lee SH; Jeong EG; Yoo NJ; Lee SH
    APMIS; 2007 Dec; 115(12):1357-63. PubMed ID: 18184405
    [TBL] [Abstract][Full Text] [Related]  

  • 23. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
    Weng AP; Millholland JM; Yashiro-Ohtani Y; Arcangeli ML; Lau A; Wai C; Del Bianco C; Rodriguez CG; Sai H; Tobias J; Li Y; Wolfe MS; Shachaf C; Felsher D; Blacklow SC; Pear WS; Aster JC
    Genes Dev; 2006 Aug; 20(15):2096-109. PubMed ID: 16847353
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia.
    Mendes RD; Canté-Barrett K; Pieters R; Meijerink JP
    Haematologica; 2016 Sep; 101(9):1010-7. PubMed ID: 27582570
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia.
    Durinck K; Wallaert A; Van de Walle I; Van Loocke W; Volders PJ; Vanhauwaert S; Geerdens E; Benoit Y; Van Roy N; Poppe B; Soulier J; Cools J; Mestdagh P; Vandesompele J; Rondou P; Van Vlierberghe P; Taghon T; Speleman F
    Haematologica; 2014 Dec; 99(12):1808-16. PubMed ID: 25344525
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors.
    Yuan JS; Tan JB; Visan I; Matei IR; Urbanellis P; Xu K; Danska JS; Egan SE; Guidos CJ
    Blood; 2011 Jan; 117(4):1184-95. PubMed ID: 21097675
    [TBL] [Abstract][Full Text] [Related]  

  • 27. IL-7R is essential for leukemia-initiating cell activity of T-cell acute lymphoblastic leukemia.
    González-García S; Mosquera M; Fuentes P; Palumbo T; Escudero A; Pérez-Martínez A; Ramírez M; Corcoran AE; Toribio ML
    Blood; 2019 Dec; 134(24):2171-2182. PubMed ID: 31530562
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.
    Gómez-del Arco P; Kashiwagi M; Jackson AF; Naito T; Zhang J; Liu F; Kee B; Vooijs M; Radtke F; Redondo JM; Georgopoulos K
    Immunity; 2010 Nov; 33(5):685-98. PubMed ID: 21093322
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.
    Malyukova A; Dohda T; von der Lehr N; Akhoondi S; Corcoran M; Heyman M; Spruck C; Grandér D; Lendahl U; Sangfelt O
    Cancer Res; 2007 Jun; 67(12):5611-6. PubMed ID: 17575125
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc.
    Sharma VM; Calvo JA; Draheim KM; Cunningham LA; Hermance N; Beverly L; Krishnamoorthy V; Bhasin M; Capobianco AJ; Kelliher MA
    Mol Cell Biol; 2006 Nov; 26(21):8022-31. PubMed ID: 16954387
    [TBL] [Abstract][Full Text] [Related]  

  • 31. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
    Hales EC; Taub JW; Matherly LH
    Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
    [TBL] [Abstract][Full Text] [Related]  

  • 32. β-Catenin is required for T-cell leukemia initiation and MYC transcription downstream of Notch1.
    Gekas C; D'Altri T; Aligué R; González J; Espinosa L; Bigas A
    Leukemia; 2016 Oct; 30(10):2002-2010. PubMed ID: 27125305
    [TBL] [Abstract][Full Text] [Related]  

  • 33. miR-22-3p Negatively Affects Tumor Progression in T-Cell Acute Lymphoblastic Leukemia.
    Saccomani V; Grassi A; Piovan E; Bongiovanni D; Di Martino L; Minuzzo S; Tosello V; Zanovello P
    Cells; 2020 Jul; 9(7):. PubMed ID: 32708470
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The NOTCH1/CD44 axis drives pathogenesis in a T cell acute lymphoblastic leukemia model.
    García-Peydró M; Fuentes P; Mosquera M; García-León MJ; Alcain J; Rodríguez A; García de Miguel P; Menéndez P; Weijer K; Spits H; Scadden DT; Cuesta-Mateos C; Muñoz-Calleja C; Sánchez-Madrid F; Toribio ML
    J Clin Invest; 2018 Jul; 128(7):2802-2818. PubMed ID: 29781813
    [TBL] [Abstract][Full Text] [Related]  

  • 35. NOTCH1-Induced T-Cell Acute Lymphoblastic Leukemia In Vivo Models.
    Campagnari A; Belver L
    Methods Mol Biol; 2024; 2773():9-24. PubMed ID: 38236532
    [TBL] [Abstract][Full Text] [Related]  

  • 36. CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors.
    Palomero T; Barnes KC; Real PJ; Glade Bender JL; Sulis ML; Murty VV; Colovai AI; Balbin M; Ferrando AA
    Leukemia; 2006 Jul; 20(7):1279-87. PubMed ID: 16688224
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia.
    Palomero T; Dominguez M; Ferrando AA
    Cell Cycle; 2008 Apr; 7(8):965-70. PubMed ID: 18414037
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Notch protection against apoptosis in T-ALL cells mediated by GIMAP5.
    Chadwick N; Zeef L; Portillo V; Boros J; Hoyle S; van Doesburg JC; Buckle AM
    Blood Cells Mol Dis; 2010 Oct; 45(3):201-9. PubMed ID: 20817506
    [TBL] [Abstract][Full Text] [Related]  

  • 39. High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling.
    Medyouf H; Gusscott S; Wang H; Tseng JC; Wai C; Nemirovsky O; Trumpp A; Pflumio F; Carboni J; Gottardis M; Pollak M; Kung AL; Aster JC; Holzenberger M; Weng AP
    J Exp Med; 2011 Aug; 208(9):1809-22. PubMed ID: 21807868
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
    Vilimas T; Mascarenhas J; Palomero T; Mandal M; Buonamici S; Meng F; Thompson B; Spaulding C; Macaroun S; Alegre ML; Kee BL; Ferrando A; Miele L; Aifantis I
    Nat Med; 2007 Jan; 13(1):70-7. PubMed ID: 17173050
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.