BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 18680316)

  • 1. Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes.
    Grillo MP; Hua F
    Chem Res Toxicol; 2008 Sep; 21(9):1749-59. PubMed ID: 18680316
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanistic studies on the bioactivation of diclofenac: identification of diclofenac-S-acyl-glutathione in vitro in incubations with rat and human hepatocytes.
    Grillo MP; Hua F; Knutson CG; Ware JA; Li C
    Chem Res Toxicol; 2003 Nov; 16(11):1410-7. PubMed ID: 14615966
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes.
    Grillo MP; Wait JC; Tadano Lohr M; Khera S; Benet LZ
    Drug Metab Dispos; 2010 Jan; 38(1):133-42. PubMed ID: 19786506
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of zomepirac-S-acyl-glutathione in vitro in incubations with rat hepatocytes and in vivo in rat bile.
    Grillo MP; Hua F
    Drug Metab Dispos; 2003 Nov; 31(11):1429-36. PubMed ID: 14570776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of enantioselective metabolism and inversion of ibuprofen by xenobiotics in isolated rat hepatocytes.
    Xiaotao Q; Hall SD
    J Pharmacol Exp Ther; 1993 Aug; 266(2):845-51. PubMed ID: 8355212
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic inversion of (R)-ibuprofen. Formation of ibuprofenyl-coenzyme A.
    Tracy TS; Wirthwein DP; Hall SD
    Drug Metab Dispos; 1993; 21(1):114-20. PubMed ID: 8095203
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enantioselective covalent binding of 2-phenylpropionic Acid to protein in vitro in rat hepatocytes.
    Li C; Benet LZ; Grillo MP
    Chem Res Toxicol; 2002 Nov; 15(11):1480-7. PubMed ID: 12437340
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Studies on the chemical reactivity of 2-phenylpropionic acid 1-O-acyl glucuronide and S-acyl-CoA thioester metabolites.
    Li C; Benet LZ; Grillo MP
    Chem Res Toxicol; 2002 Oct; 15(10):1309-17. PubMed ID: 12387630
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of alpha-fluorination of valproic acid on valproyl-S-acyl-CoA formation in vivo in rats.
    Grillo MP; Chiellini G; Tonelli M; Benet LZ
    Drug Metab Dispos; 2001 Sep; 29(9):1210-5. PubMed ID: 11502730
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Studies on the reactivity of clofibryl-S-acyl-CoA thioester with glutathione in vitro.
    Grillo MP; Benet LZ
    Drug Metab Dispos; 2002 Jan; 30(1):55-62. PubMed ID: 11744612
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Taurine conjugation of ibuprofen in humans and in rat liver in vitro. Relationship to metabolic chiral inversion.
    Shirley MA; Guan X; Kaiser DG; Halstead GW; Baillie TA
    J Pharmacol Exp Ther; 1994 Jun; 269(3):1166-75. PubMed ID: 8014860
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bioactivation of a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, via glucuronidation. LC/MS/MS characterization of the GSH-glucuronide diconjugates.
    Tang W; Abbott FS
    Chem Res Toxicol; 1996 Mar; 9(2):517-26. PubMed ID: 8839057
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Studies on the chemical reactivity of diclofenac acyl glucuronide with glutathione: identification of diclofenac-S-acyl-glutathione in rat bile.
    Grillo MP; Knutson CG; Sanders PE; Waldon DJ; Hua F; Ware JA
    Drug Metab Dispos; 2003 Nov; 31(11):1327-36. PubMed ID: 14570764
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Studies on the metabolism and chiral inversion of ibuprofen in isolated rat hepatocytes.
    Sanins SM; Adams WJ; Kaiser DG; Halstead GW; Baillie TA
    Drug Metab Dispos; 1990; 18(4):527-33. PubMed ID: 1976078
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Formation of protein-glutathione mixed disulfides in the developing rat conceptus following diamide treatment in vitro.
    Hiranruengchok R; Harris C
    Teratology; 1995 Oct; 52(4):196-204. PubMed ID: 8838289
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enantioselective effects of experimental diabetes mellitus on the metabolism of ibuprofen.
    Oian X; Hall SD
    J Pharmacol Exp Ther; 1995 Sep; 274(3):1192-8. PubMed ID: 7562487
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro studies on the chemical reactivity of 2,4-dichlorophenoxyacetyl-S-acyl-CoA thioester.
    Li C; Grillo MP; Benet LZ
    Toxicol Appl Pharmacol; 2003 Mar; 187(2):101-9. PubMed ID: 12649042
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Formation of glycine conjugate and (-)-(R)-enantiomer from (+)-(S)-2-phenylpropionic acid suggesting the formation of the CoA thioester intermediate of (+)-(S)-enantiomer in dogs.
    Tanaka Y; Shimomura Y; Hirota T; Nozaki A; Ebata M; Takasaki W; Shigehara E; Hayashi R; Caldwell J
    Chirality; 1992; 4(6):342-8. PubMed ID: 1449948
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization and formation of the glutathione conjugate of clofibric acid.
    Shore LJ; Fenselau C; King AR; Dickinson RG
    Drug Metab Dispos; 1995 Jan; 23(1):119-23. PubMed ID: 7720514
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanistic studies on the metabolic chiral inversion of R-ibuprofen in the rat.
    Sanins SM; Adams WJ; Kaiser DG; Halstead GW; Hosley J; Barnes H; Baillie TA
    Drug Metab Dispos; 1991; 19(2):405-10. PubMed ID: 1676645
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.