BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 18680359)

  • 1. Inhibitors of Src homology-2 domain containing protein tyrosine phosphatase-2 (Shp2) based on oxindole scaffolds.
    Lawrence HR; Pireddu R; Chen L; Luo Y; Sung SS; Szymanski AM; Yip ML; Guida WC; Sebti SM; Wu J; Lawrence NJ
    J Med Chem; 2008 Aug; 51(16):4948-56. PubMed ID: 18680359
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Benzo[c][1,2,5]thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors.
    Wang WL; Chen XY; Gao Y; Gao LX; Sheng L; Zhu J; Xu L; Ding ZZ; Zhang C; Li JY; Li J; Zhou YB
    Bioorg Med Chem Lett; 2017 Dec; 27(23):5154-5157. PubMed ID: 29100798
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors.
    Satheeshkumar R; Zhu R; Feng B; Huang C; Gao Y; Gao LX; Shen C; Hou TJ; Xu L; Li J; Zhu YL; Zhou YB; Wang WL
    Bioorg Med Chem Lett; 2020 Jun; 30(11):127170. PubMed ID: 32273218
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of small peptide compounds, molecular docking, and inhibitory activity evaluation against phosphatases PTP1B and SHP2.
    Kostrzewa T; Sahu KK; Gorska-Ponikowska M; Tuszynski JA; Kuban-Jankowska A
    Drug Des Devel Ther; 2018; 12():4139-4147. PubMed ID: 30584278
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polyphyllin D Shows Anticancer Effect through a Selective Inhibition of Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP2).
    Kwon SJ; Ahn D; Yang HM; Kang HJ; Chung SJ
    Molecules; 2021 Feb; 26(4):. PubMed ID: 33562835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
    Zhang X; He Y; Liu S; Yu Z; Jiang ZX; Yang Z; Dong Y; Nabinger SC; Wu L; Gunawan AM; Wang L; Chan RJ; Zhang ZY
    J Med Chem; 2010 Mar; 53(6):2482-93. PubMed ID: 20170098
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112.
    Chen L; Pernazza D; Scott LM; Lawrence HR; Ren Y; Luo Y; Wu X; Sung SS; Guida WC; Sebti SM; Lawrence NJ; Wu J
    Biochem Pharmacol; 2010 Sep; 80(6):801-10. PubMed ID: 20510203
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors.
    Meng XD; Gao LX; Wang ZJ; Feng B; Zhang C; Satheeshkumar R; Li J; Zhu YL; Zhou YB; Wang WL
    Bioorg Chem; 2021 Nov; 116():105384. PubMed ID: 34601294
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting Oncogenic Src Homology 2 Domain-Containing Phosphatase 2 (SHP2) by Inhibiting Its Protein-Protein Interactions.
    Bobone S; Pannone L; Biondi B; Solman M; Flex E; Canale VC; Calligari P; De Faveri C; Gandini T; Quercioli A; Torini G; Venditti M; Lauri A; Fasano G; Hoeksma J; Santucci V; Cattani G; Bocedi A; Carpentieri G; Tirelli V; Sanchez M; Peggion C; Formaggio F; den Hertog J; Martinelli S; Bocchinfuso G; Tartaglia M; Stella L
    J Med Chem; 2021 Nov; 64(21):15973-15990. PubMed ID: 34714648
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dinuclear copper complexes of organic claw: potent inhibition of protein tyrosine phosphatases.
    Ma L; Lu L; Zhu M; Wang Q; Gao F; Yuan C; Wu Y; Xing S; Fu X; Mei Y; Gao X
    J Inorg Biochem; 2011 Sep; 105(9):1138-47. PubMed ID: 21708098
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis.
    Geer MJ; van Geffen JP; Gopalasingam P; Vögtle T; Smith CW; Heising S; Kuijpers MJE; Tullemans BME; Jarvis GE; Eble JA; Jeeves M; Overduin M; Heemskerk JWM; Mazharian A; Senis YA
    Blood; 2018 Sep; 132(13):1413-1425. PubMed ID: 29891536
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of a novel shp2 protein tyrosine phosphatase inhibitor.
    Chen L; Sung SS; Yip ML; Lawrence HR; Ren Y; Guida WC; Sebti SM; Lawrence NJ; Wu J
    Mol Pharmacol; 2006 Aug; 70(2):562-70. PubMed ID: 16717135
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting protein tyrosine phosphatase SHP2 for the treatment of PTPN11-associated malignancies.
    Yu B; Liu W; Yu WM; Loh ML; Alter S; Guvench O; Mackerell AD; Tang LD; Qu CK
    Mol Cancer Ther; 2013 Sep; 12(9):1738-48. PubMed ID: 23825065
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A procedure combining molecular docking and semiempirical method PM7 for identification of selective Shp2 inhibitors.
    Rocha SFLS; Sant'Anna CMR
    Biopolymers; 2019 Nov; 110(11):e23320. PubMed ID: 31268558
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors.
    Klopfenstein SR; Evdokimov AG; Colson AO; Fairweather NT; Neuman JJ; Maier MB; Gray JL; Gerwe GS; Stake GE; Howard BW; Farmer JA; Pokross ME; Downs TR; Kasibhatla B; Peters KG
    Bioorg Med Chem Lett; 2006 Mar; 16(6):1574-8. PubMed ID: 16386905
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Y-shaped bis-arylethenesulfonic acid esters: Potential potent and membrane permeable protein tyrosine phosphatase 1B inhibitors.
    Yang F; Xie F; Zhang Y; Xia Y; Liu W; Jiang F; Lam C; Qiao Y; Xie D; Li J; Fu L
    Bioorg Med Chem Lett; 2017 May; 27(10):2166-2170. PubMed ID: 28372909
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening.
    Yu ZH; Chen L; Wu L; Liu S; Wang L; Zhang ZY
    Bioorg Med Chem Lett; 2011 Jul; 21(14):4238-42. PubMed ID: 21669525
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A multifunctional cross-validation high-throughput screening protocol enabling the discovery of new SHP2 inhibitors.
    Song Y; Zhao M; Wu Y; Yu B; Liu HM
    Acta Pharm Sin B; 2021 Mar; 11(3):750-762. PubMed ID: 33777680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Marine alkaloid rigidin analogues as potential selective inhibitors of SHP1, a new strategy for cancer immunotherapeutics.
    Bhasin S; Das A
    J Biomol Struct Dyn; 2024 Jul; 42(11):5590-5606. PubMed ID: 37349914
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SHP1 and SHP2 protein-tyrosine phosphatases associate with betac after interleukin-3-induced receptor tyrosine phosphorylation. Identification of potential binding sites and substrates.
    Bone H; Dechert U; Jirik F; Schrader JW; Welham MJ
    J Biol Chem; 1997 May; 272(22):14470-6. PubMed ID: 9162089
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.