BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 18680471)

  • 1. Arylamine N-acetyltransferases in mycobacteria.
    Sim E; Sandy J; Evangelopoulos D; Fullam E; Bhakta S; Westwood I; Krylova A; Lack N; Noble M
    Curr Drug Metab; 2008 Jul; 9(6):510-9. PubMed ID: 18680471
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arylamine N-acetyltransferases: from structure to function.
    Sim E; Walters K; Boukouvala S
    Drug Metab Rev; 2008; 40(3):479-510. PubMed ID: 18642144
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Arylamine N-acetyltransferases: a pharmacogenomic approach to drug metabolism and endogenous function.
    Sim E; Pinter K; Mushtaq A; Upton A; Sandy J; Bhakta S; Noble M
    Biochem Soc Trans; 2003 Jun; 31(Pt 3):615-9. PubMed ID: 12773167
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Divergence of cofactor recognition across evolution: coenzyme A binding in a prokaryotic arylamine N-acetyltransferase.
    Fullam E; Westwood IM; Anderton MC; Lowe ED; Sim E; Noble ME
    J Mol Biol; 2008 Jan; 375(1):178-91. PubMed ID: 18005984
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery.
    Sim E; Abuhammad A; Ryan A
    Br J Pharmacol; 2014 Jun; 171(11):2705-25. PubMed ID: 24467436
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arylamine N-acetyltransferases - of mice, men and microorganisms.
    Upton A; Johnson N; Sandy J; Sim E
    Trends Pharmacol Sci; 2001 Mar; 22(3):140-6. PubMed ID: 11239577
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid.
    Sandy J; Mushtaq A; Kawamura A; Sinclair J; Sim E; Noble M
    J Mol Biol; 2002 May; 318(4):1071-83. PubMed ID: 12054803
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
    Sim E; Lack N; Wang CJ; Long H; Westwood I; Fullam E; Kawamura A
    Toxicology; 2008 Dec; 254(3):170-83. PubMed ID: 18852012
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Arylamine N-acetyltransferase of Mycobacterium tuberculosis is a polymorphic enzyme and a site of isoniazid metabolism.
    Upton AM; Mushtaq A; Victor TC; Sampson SL; Sandy J; Smith DM; van Helden PV; Sim E
    Mol Microbiol; 2001 Oct; 42(2):309-17. PubMed ID: 11703656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cloning and characterization of arylamine N-acetyltransferase genes from Mycobacterium smegmatis and Mycobacterium tuberculosis: increased expression results in isoniazid resistance.
    Payton M; Auty R; Delgoda R; Everett M; Sim E
    J Bacteriol; 1999 Feb; 181(4):1343-7. PubMed ID: 9973365
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Arylamine N-acetyltransferases: what we learn from genes and genomes.
    Boukouvala S; Fakis G
    Drug Metab Rev; 2005; 37(3):511-64. PubMed ID: 16257833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site.
    Abuhammad AM; Lowe ED; Fullam E; Noble M; Garman EF; Sim E
    Protein Cell; 2010 Apr; 1(4):384-392. PubMed ID: 21203950
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages.
    Abuhammad A; Fullam E; Lowe ED; Staunton D; Kawamura A; Westwood IM; Bhakta S; Garner AC; Wilson DL; Seden PT; Davies SG; Russell AJ; Garman EF; Sim E
    PLoS One; 2012; 7(12):e52790. PubMed ID: 23285185
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis.
    Sandy J; Holton S; Fullam E; Sim E; Noble M
    Protein Sci; 2005 Mar; 14(3):775-82. PubMed ID: 15722451
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence towards the role of arylamine N-acetyltransferase in Mycobacterium smegmatis and development of a specific antiserum against the homologous enzyme of Mycobacterium tuberculosis.
    Payton M; Gifford C; Schartau P; Hagemeier C; Mushtaq A; Lucas S; Pinter K; Sim E
    Microbiology (Reading); 2001 Dec; 147(Pt 12):3295-302. PubMed ID: 11739761
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.
    Fullam E; Kawamura A; Wilkinson H; Abuhammad A; Westwood I; Sim E
    Protein J; 2009 Aug; 28(6):281-93. PubMed ID: 19636684
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target.
    Bhakta S; Besra GS; Upton AM; Parish T; Sholto-Douglas-Vernon C; Gibson KJ; Knutton S; Gordon S; DaSilva RP; Anderton MC; Sim E
    J Exp Med; 2004 May; 199(9):1191-9. PubMed ID: 15117974
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The pharmacogenetics of NAT: structural aspects.
    Pompeo F; Brooke E; Kawamura A; Mushtaq A; Sim E
    Pharmacogenomics; 2002 Jan; 3(1):19-30. PubMed ID: 11966400
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The COOH terminus of arylamine N-acetyltransferase from Salmonella typhimurium controls enzymic activity.
    Mushtaq A; Payton M; Sim E
    J Biol Chem; 2002 Apr; 277(14):12175-81. PubMed ID: 11799105
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines.
    Sandy J; Mushtaq A; Holton SJ; Schartau P; Noble ME; Sim E
    Biochem J; 2005 Aug; 390(Pt 1):115-23. PubMed ID: 15869465
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.