These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 18682569)

  • 1. Use of acetylcholine mustard to study allosteric interactions at the M(2) muscarinic receptor.
    Suga H; Figueroa KW; Ehlert FJ
    J Pharmacol Exp Ther; 2008 Nov; 327(2):518-28. PubMed ID: 18682569
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Investigating the interaction of McN-A-343 with the M2 muscarinic receptor using its nitrogen mustard derivative.
    Suga H; Ehlert FJ
    Biochem Pharmacol; 2010 Apr; 79(7):1025-35. PubMed ID: 19913516
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigating the interaction of McN-A-343 with the M muscarinic receptor using its nitrogen mustard derivative and ACh mustard.
    Figueroa KW; Suga H; Ehlert FJ
    Br J Pharmacol; 2010 Jul; 160(6):1534-49. PubMed ID: 20590642
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutagenesis of nucleophilic residues near the orthosteric binding pocket of M1 and M2 muscarinic receptors: effect on the binding of nitrogen mustard analogs of acetylcholine and McN-A-343.
    Suga H; Sawyer GW; Ehlert FJ
    Mol Pharmacol; 2010 Oct; 78(4):745-55. PubMed ID: 20643905
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interaction studies of multiple binding sites on m4 muscarinic acetylcholine receptors.
    Lanzafame AA; Sexton PM; Christopoulos A
    Mol Pharmacol; 2006 Aug; 70(2):736-46. PubMed ID: 16709648
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors.
    May LT; Avlani VA; Langmead CJ; Herdon HJ; Wood MD; Sexton PM; Christopoulos A
    Mol Pharmacol; 2007 Aug; 72(2):463-76. PubMed ID: 17525129
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of asparagine mutagenesis of conserved aspartic acids in helix 2 (D2.50) and 3 (D3.32) of M1-M4 muscarinic receptors on the irreversible binding of nitrogen mustard analogs of acetylcholine and McN-A-343.
    Suga H; Ehlert FJ
    Biochemistry; 2013 Jul; 52(29):4914-28. PubMed ID: 23826889
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist.
    Grossmüller M; Antony J; Tränkle C; Holzgrabe U; Mohr K
    Naunyn Schmiedebergs Arch Pharmacol; 2006 Jan; 372(4):267-76. PubMed ID: 16362429
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modes of allosteric interactions with free and [3H]N-methylscopolamine-occupied muscarinic M2 receptors as deduced from buffer-dependent potency shifts.
    Schröter A; Tränkle C; Mohr K
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Dec; 362(6):512-9. PubMed ID: 11138843
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors.
    Lazareno S; Popham A; Birdsall NJ
    Mol Pharmacol; 2002 Dec; 62(6):1492-505. PubMed ID: 12435818
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of a radioligand, [(3)H]LY2119620, to probe the human M(2) and M(4) muscarinic receptor allosteric binding sites.
    Schober DA; Croy CH; Xiao H; Christopoulos A; Felder CC
    Mol Pharmacol; 2014 Jul; 86(1):116-23. PubMed ID: 24807966
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Allosteric regulation of the binding of [3H]acetylcholine to m2 muscarinic receptors.
    Gnagey A; Ellis J
    Biochem Pharmacol; 1996 Dec; 52(11):1767-75. PubMed ID: 8986140
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric interaction of the neuromuscular blockers vecuronium and pancuronium with recombinant human muscarinic M2 receptors.
    Cembala TM; Forde SC; Appadu BL; Lambert DG
    Eur J Pharmacol; 2007 Aug; 569(1-2):37-40. PubMed ID: 17588565
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Muscarinic allosteric modulation: M2/M3 subtype selectivity of gallamine is independent of G-protein coupling specificity.
    Tränkle C; Kostenis E; Mohr K
    Naunyn Schmiedebergs Arch Pharmacol; 2001 Aug; 364(2):172-8. PubMed ID: 11534857
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of M2 muscarinic acetylcholine receptor expression and signaling by prolonged exposure to allosteric modulators.
    May LT; Lin Y; Sexton PM; Christopoulos A
    J Pharmacol Exp Ther; 2005 Jan; 312(1):382-90. PubMed ID: 15333678
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Using a radioalloster to test predictions of the cooperativity model for gallamine binding to the allosteric site of muscarinic acetylcholine M(2) receptors.
    Tränkle C; Weyand O; Schröter A; Mohr K
    Mol Pharmacol; 1999 Nov; 56(5):962-5. PubMed ID: 10531401
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The binding of a 2-chloroethylamine derivative of oxotremorine (BM 123) to muscarinic receptors in the rat cerebral cortex.
    Ehlert FJ; Jenden DJ
    Mol Pharmacol; 1985 Aug; 28(2):107-19. PubMed ID: 3839562
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the M2 muscarinic receptor.
    Steinfeld T; Mammen M; Smith JA; Wilson RD; Jasper JR
    Mol Pharmacol; 2007 Aug; 72(2):291-302. PubMed ID: 17478612
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Conversion of N-(2-chloroethyl)-4-piperidinyl diphenylacetate (4-DAMP mustard) to an aziridinium ion and its interaction with muscarinic receptors in various tissues.
    Thomas EA; Hsu HH; Griffin MT; Hunter AL; Luong T; Ehlert FJ
    Mol Pharmacol; 1992 Apr; 41(4):718-26. PubMed ID: 1569923
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Testing the specificity of allosteric modulators of muscarinic receptors in phylogenetically closely related histamine H1-receptors.
    Franken C; Tränkle C; Mohr K
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Feb; 361(2):107-12. PubMed ID: 10685864
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.