199 related articles for article (PubMed ID: 18687346)
21. Regional and cellular expression of CYP2D6 in human brain: higher levels in alcoholics.
Miksys S; Rao Y; Hoffmann E; Mash DC; Tyndale RF
J Neurochem; 2002 Sep; 82(6):1376-87. PubMed ID: 12354285
[TBL] [Abstract][Full Text] [Related]
22. Rat brain CYP2D enzymatic metabolism alters acute and chronic haloperidol side-effects by different mechanisms.
Miksys S; Wadji FB; Tolledo EC; Remington G; Nobrega JN; Tyndale RF
Prog Neuropsychopharmacol Biol Psychiatry; 2017 Aug; 78():140-148. PubMed ID: 28454738
[TBL] [Abstract][Full Text] [Related]
23. Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver.
Howard LA; Micu AL; Sellers EM; Tyndale RF
J Pharmacol Exp Ther; 2001 Nov; 299(2):542-50. PubMed ID: 11602665
[TBL] [Abstract][Full Text] [Related]
24. The endogenous substrates of brain CYP2D.
Wang X; Li J; Dong G; Yue J
Eur J Pharmacol; 2014 Feb; 724():211-8. PubMed ID: 24374199
[TBL] [Abstract][Full Text] [Related]
25. Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics.
Howard LA; Miksys S; Hoffmann E; Mash D; Tyndale RF
Br J Pharmacol; 2003 Apr; 138(7):1376-86. PubMed ID: 12711639
[TBL] [Abstract][Full Text] [Related]
26. The Atypical Antipsychotic Lurasidone Affects Brain but Not Liver Cytochrome P450 2D (CYP2D) Activity. A Comparison with Other Novel Neuroleptics and Significance for Drug Treatment of Schizophrenia.
Danek PJ; Daniel WA
Cells; 2022 Nov; 11(21):. PubMed ID: 36359909
[TBL] [Abstract][Full Text] [Related]
27. Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates.
Quik M; Parameswaran N; McCallum SE; Bordia T; Bao S; McCormack A; Kim A; Tyndale RF; Langston JW; Di Monte DA
J Neurochem; 2006 Sep; 98(6):1866-75. PubMed ID: 16882311
[TBL] [Abstract][Full Text] [Related]
28. Regional distribution of cytochrome P450 2D1 in the rat central nervous system.
Norris PJ; Hardwick JP; Emson PC
J Comp Neurol; 1996 Mar; 366(2):244-58. PubMed ID: 8698885
[TBL] [Abstract][Full Text] [Related]
29. Down-regulation of hepatic nicotine metabolism and a CYP2A6-like enzyme in African green monkeys after long-term nicotine administration.
Schoedel KA; Sellers EM; Palmour R; Tyndale RF
Mol Pharmacol; 2003 Jan; 63(1):96-104. PubMed ID: 12488541
[TBL] [Abstract][Full Text] [Related]
30. Constitutive expression and localization of the major drug metabolizing enzyme, cytochrome P4502D in human brain.
Chinta SJ; Pai HV; Upadhya SC; Boyd MR; Ravindranath V
Brain Res Mol Brain Res; 2002 Jun; 103(1-2):49-61. PubMed ID: 12106691
[TBL] [Abstract][Full Text] [Related]
31. Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism.
Micu AL; Miksys S; Sellers EM; Koop DR; Tyndale RF
J Pharmacol Exp Ther; 2003 Sep; 306(3):941-7. PubMed ID: 12750430
[TBL] [Abstract][Full Text] [Related]
32. Chronic nicotine treatment increases nAChRs and microglial expression in monkey substantia nigra after nigrostriatal damage.
Quik M; Campos C; Parameswaran N; Langston JW; McIntosh JM; Yeluashvili M
J Mol Neurosci; 2010 Jan; 40(1-2):105-13. PubMed ID: 19685015
[TBL] [Abstract][Full Text] [Related]
33. Human CYP2D6 Is Functional in Brain In Vivo: Evidence from Humanized CYP2D6 Transgenic Mice.
Tolledo C; Stocco MR; Miksys S; Gonzalez FJ; Tyndale RF
Mol Neurobiol; 2020 Jun; 57(6):2509-2520. PubMed ID: 32189192
[TBL] [Abstract][Full Text] [Related]
34. Human CYP2D6 in the Brain Is Protective Against Harmine-Induced Neurotoxicity: Evidence from Humanized CYP2D6 Transgenic Mice.
Stocco MR; Tolledo C; Wadji FB; Gonzalez FJ; Miksys S; Tyndale RF
Mol Neurobiol; 2020 Nov; 57(11):4608-4621. PubMed ID: 32761352
[TBL] [Abstract][Full Text] [Related]
35. Long-Term Treatment with Atypical Antipsychotic Iloperidone Modulates Cytochrome P450 2D (CYP2D) Expression and Activity in the Liver and Brain via Different Mechanisms.
Danek PJ; Daniel WA
Cells; 2021 Dec; 10(12):. PubMed ID: 34943983
[No Abstract] [Full Text] [Related]
36. First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo.
Zhou K; Khokhar JY; Zhao B; Tyndale RF
Biochem Pharmacol; 2013 Jun; 85(12):1848-55. PubMed ID: 23623752
[TBL] [Abstract][Full Text] [Related]
37. The activity of brain and liver cytochrome P450 2D (CYP2D) is differently affected by antidepressants in the chronic mild stress (CMS) model of depression in the rat.
Haduch A; Rysz M; Papp M; Daniel WA
Biochem Pharmacol; 2018 Oct; 156():398-405. PubMed ID: 30195732
[TBL] [Abstract][Full Text] [Related]
38. Nicotine and caffeine-mediated modulation in the expression of toxicant responsive genes and vesicular monoamine transporter-2 in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype in mouse.
Singh S; Singh K; Patel S; Patel DK; Singh C; Nath C; Singh MP
Brain Res; 2008 May; 1207():193-206. PubMed ID: 18374908
[TBL] [Abstract][Full Text] [Related]
39. Molecular cloning and expression of cytochrome P450 2D6 in the livers of domestic cats.
Komatsu T; Honda K; Kubota A; Kitazawa T; Hiraga T; Teraoka H
J Vet Med Sci; 2010 Dec; 72(12):1633-6. PubMed ID: 20661004
[TBL] [Abstract][Full Text] [Related]
40. Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain.
Schoedel KA; Sellers EM; Tyndale RF
Biochem Pharmacol; 2001 Oct; 62(8):1025-36. PubMed ID: 11597571
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
