These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 18687690)

  • 1. AML1/RUNX1 works as a negative regulator of c-Mpl in hematopoietic stem cells.
    Satoh Y; Matsumura I; Tanaka H; Ezoe S; Fukushima K; Tokunaga M; Yasumi M; Shibayama H; Mizuki M; Era T; Okuda T; Kanakura Y
    J Biol Chem; 2008 Oct; 283(44):30045-56. PubMed ID: 18687690
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Low Mpl receptor expression in a pedigree with familial platelet disorder with predisposition to acute myelogenous leukemia and a novel AML1 mutation.
    Heller PG; Glembotsky AC; Gandhi MJ; Cummings CL; Pirola CJ; Marta RF; Kornblihtt LI; Drachman JG; Molinas FC
    Blood; 2005 Jun; 105(12):4664-70. PubMed ID: 15741216
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO.
    Chou FS; Griesinger A; Wunderlich M; Lin S; Link KA; Shrestha M; Goyama S; Mizukawa B; Shen S; Marcucci G; Mulloy JC
    Blood; 2012 Jul; 120(4):709-19. PubMed ID: 22337712
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thrombopoietin does not induce lineage-restricted commitment of Mpl-R expressing pluripotent progenitors but permits their complete erythroid and megakaryocytic differentiation.
    Goncalves F; Lacout C; Villeval JL; Wendling F; Vainchenker W; Dumenil D
    Blood; 1997 May; 89(10):3544-53. PubMed ID: 9160659
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis.
    Ichikawa M; Goyama S; Asai T; Kawazu M; Nakagawa M; Takeshita M; Chiba S; Ogawa S; Kurokawa M
    J Immunol; 2008 Apr; 180(7):4402-8. PubMed ID: 18354160
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lentiviral gene transfer regenerates hematopoietic stem cells in a mouse model for Mpl-deficient aplastic anemia.
    Heckl D; Wicke DC; Brugman MH; Meyer J; Schambach A; Büsche G; Ballmaier M; Baum C; Modlich U
    Blood; 2011 Apr; 117(14):3737-47. PubMed ID: 21289307
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis.
    Fleury M; Petit-Cocault L; Clay D; Souyri M
    Int J Dev Biol; 2010; 54(6-7):1067-74. PubMed ID: 20711984
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Top-down motif engineering of a cytokine receptor for directing ex vivo expansion of hematopoietic stem cells.
    Saka K; Kawahara M; Teng J; Otsu M; Nakauchi H; Nagamune T
    J Biotechnol; 2013 Dec; 168(4):659-65. PubMed ID: 24070902
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Embryonic stem cell differentiation to hematopoietic cells: A model to study the function of various regions of the intracytoplasmic domain of cytokine receptors in vitro.
    Filippi MD; Porteu F; Le Pesteur F; Rameau P; Nogueira MM; Debili N; Vainchenker W; de Sauvage FJ; Kupperschmitt AD; Sainteny F
    Exp Hematol; 2000 Dec; 28(12):1363-72. PubMed ID: 11146158
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Incomplete restoration of Mpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis.
    Lannutti BJ; Epp A; Roy J; Chen J; Josephson NC
    Blood; 2009 Feb; 113(8):1778-85. PubMed ID: 18796624
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Endothelial protein C receptor supports hematopoietic stem cell engraftment and expansion in Mpl-deficient mice.
    Kohlscheen S; Schenk F; Rommel MGE; Cullmann K; Modlich U
    Blood; 2019 Mar; 133(13):1465-1478. PubMed ID: 30683655
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular pathways mediating MDS/AML with focus on AML1/RUNX1 point mutations.
    Harada Y; Harada H
    J Cell Physiol; 2009 Jul; 220(1):16-20. PubMed ID: 19334039
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells.
    Mulloy JC; Cammenga J; MacKenzie KL; Berguido FJ; Moore MA; Nimer SD
    Blood; 2002 Jan; 99(1):15-23. PubMed ID: 11756147
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes.
    Tiedt R; Coers J; Ziegler S; Wiestner A; Hao-Shen H; Bornmann C; Schenkel J; Karakhanova S; de Sauvage FJ; Jackson CW; Skoda RC
    Blood; 2009 Feb; 113(8):1768-77. PubMed ID: 18845793
    [TBL] [Abstract][Full Text] [Related]  

  • 15. AML1/ETO trans-activates c-KIT expression through the long range interaction between promoter and intronic enhancer.
    Tian Y; Wang G; Hu Q; Xiao X; Chen S
    J Cell Biochem; 2018 Apr; 119(4):3706-3715. PubMed ID: 29236325
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl.
    Alexander WS; Roberts AW; Nicola NA; Li R; Metcalf D
    Blood; 1996 Mar; 87(6):2162-70. PubMed ID: 8630375
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thrombopoietin regulates IEX-1 gene expression through ERK-induced AML1 phosphorylation.
    Hamelin V; Letourneux C; Romeo PH; Porteu F; Gaudry M
    Blood; 2006 Apr; 107(8):3106-13. PubMed ID: 16368886
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells.
    Landrette SF; Madera D; He F; Castilla LH
    Leukemia; 2011 Apr; 25(4):655-62. PubMed ID: 21263445
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo.
    Webber BR; Iacovino M; Choi SH; Tolar J; Kyba M; Blazar BR
    Blood; 2013 Oct; 122(17):2978-86. PubMed ID: 24030384
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs.
    Mandoli A; Singh AA; Prange KHM; Tijchon E; Oerlemans M; Dirks R; Ter Huurne M; Wierenga ATJ; Janssen-Megens EM; Berentsen K; Sharifi N; Kim B; Matarese F; Nguyen LN; Hubner NC; Rao NA; van den Akker E; Altucci L; Vellenga E; Stunnenberg HG; Martens JHA
    Cell Rep; 2016 Nov; 17(8):2087-2100. PubMed ID: 27851970
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.