BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 18689426)

  • 1. Cleavage of the IPS-1/Cardif/MAVS/VISA does not inhibit T cell-mediated elimination of hepatitis C virus non-structural 3/4A-expressing hepatocytes.
    Ahlén G; Derk E; Weiland M; Jiao J; Rahbin N; Aleman S; Peterson DL; Pokrovskaja K; Grandér D; Frelin L; Sällberg M
    Gut; 2009 Apr; 58(4):560-9. PubMed ID: 18689426
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense.
    Johnson CL; Owen DM; Gale M
    J Biol Chem; 2007 Apr; 282(14):10792-803. PubMed ID: 17289677
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression.
    Kaukinen P; Sillanpää M; Kotenko S; Lin R; Hiscott J; Melén K; Julkunen I
    Virol J; 2006 Sep; 3():66. PubMed ID: 16945160
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cleavage of the T cell protein tyrosine phosphatase by the hepatitis C virus nonstructural 3/4A protease induces a Th1 to Th2 shift reversible by ribavirin therapy.
    Brenndörfer ED; Brass A; Karthe J; Ahlén G; Bode JG; Sällberg M
    J Immunol; 2014 Feb; 192(4):1671-80. PubMed ID: 24442435
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hepatitis C virus variants resistant to macrocyclic NS3-4A inhibitors subvert IFN-β induction by efficient MAVS cleavage.
    Welsch C; Haselow K; Gouttenoire J; Schneider M; Morikawa K; Martinez Y; Susser S; Sarrazin C; Zeuzem S; Antes I; Moradpour D; Lange CM
    J Hepatol; 2015 Apr; 62(4):779-84. PubMed ID: 25463536
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage.
    Lin R; Lacoste J; Nakhaei P; Sun Q; Yang L; Paz S; Wilkinson P; Julkunen I; Vitour D; Meurs E; Hiscott J
    J Virol; 2006 Jun; 80(12):6072-83. PubMed ID: 16731946
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential, type I interferon-mediated autophagic trafficking of hepatitis C virus proteins in mouse liver.
    Desai MM; Gong B; Chan T; Davey RA; Soong L; Kolokoltsov AA; Sun J
    Gastroenterology; 2011 Aug; 141(2):674-85, 685.e1-6. PubMed ID: 21683701
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS.
    Chen Z; Benureau Y; Rijnbrand R; Yi J; Wang T; Warter L; Lanford RE; Weinman SA; Lemon SM; Martin A; Li K
    J Virol; 2007 Jan; 81(2):964-76. PubMed ID: 17093192
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: disruption by hepatitis C virus NS3-4A protease.
    Hiscott J; Lacoste J; Lin R
    Biochem Pharmacol; 2006 Nov; 72(11):1477-84. PubMed ID: 16876765
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Control of hepatitis C virus replication in mouse liver-derived cells by MAVS-dependent production of type I and type III interferons.
    Anggakusuma ; Frentzen A; Gürlevik E; Yuan Q; Steinmann E; Ott M; Staeheli P; Schmid-Burgk J; Schmidt T; Hornung V; Kuehnel F; Pietschmann T
    J Virol; 2015 Apr; 89(7):3833-45. PubMed ID: 25609814
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Restoration of the activated Rig-I pathway in hepatitis C virus (HCV) replicon cells by HCV protease, polymerase, and NS5A inhibitors in vitro at clinically relevant concentrations.
    Kalkeri G; Lin C; Gopilan J; Sloan K; Rijnbrand R; Kwong AD
    Antimicrob Agents Chemother; 2013 Sep; 57(9):4417-26. PubMed ID: 23836176
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepacivirus NS3/4A Proteases Interfere with MAVS Signaling in both Their Cognate Animal Hosts and Humans: Implications for Zoonotic Transmission.
    Anggakusuma ; Brown RJP; Banda DH; Todt D; Vieyres G; Steinmann E; Pietschmann T
    J Virol; 2016 Dec; 90(23):10670-10681. PubMed ID: 27654291
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MDA5 plays a critical role in interferon response during hepatitis C virus infection.
    Cao X; Ding Q; Lu J; Tao W; Huang B; Zhao Y; Niu J; Liu YJ; Zhong J
    J Hepatol; 2015 Apr; 62(4):771-8. PubMed ID: 25463548
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Double-stranded RNA-induced interferon-beta and inflammatory cytokine production modulated by hepatitis C virus serine proteases derived from patients with hepatic diseases.
    Dansako H; Ikeda M; Ariumi Y; Wakita T; Kato N
    Arch Virol; 2009; 154(5):801-10. PubMed ID: 19353241
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hepatitis C virus non-structural 3/4A protein interferes with intrahepatic interferon-γ production.
    Brenndörfer ED; Brass A; Söderholm J; Frelin L; Aleman S; Bode JG; Sällberg M
    Gut; 2012 Apr; 61(4):589-96. PubMed ID: 21813471
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hepatitis C Virus Nonstructural 3/4A Protein Dampens Inflammation and Contributes to Slow Fibrosis Progression during Chronic Fibrosis In Vivo.
    Bansal R; Frelin L; Brenndörfer ED; Storm G; Prakash J; Sällberg M
    PLoS One; 2015; 10(6):e0128466. PubMed ID: 26030283
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antiviral suppression vs restoration of RIG-I signaling by hepatitis C protease and polymerase inhibitors.
    Liang Y; Ishida H; Lenz O; Lin TI; Nyanguile O; Simmen K; Pyles RB; Bourne N; Yi M; Li K; Lemon SM
    Gastroenterology; 2008 Nov; 135(5):1710-1718.e2. PubMed ID: 18725224
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Distinct antiviral signaling pathways in primary human hepatocytes and their differential disruption by HCV NS3 protease.
    Jouan L; Melançon P; Rodrigue-Gervais IG; Raymond VA; Selliah S; Boucher G; Bilodeau M; Grandvaux N; Lamarre D
    J Hepatol; 2010 Feb; 52(2):167-75. PubMed ID: 20006398
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity.
    Nitta S; Sakamoto N; Nakagawa M; Kakinuma S; Mishima K; Kusano-Kitazume A; Kiyohashi K; Murakawa M; Nishimura-Sakurai Y; Azuma S; Tasaka-Fujita M; Asahina Y; Yoneyama M; Fujita T; Watanabe M
    Hepatology; 2013 Jan; 57(1):46-58. PubMed ID: 22911572
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anti-tumor necrosis factor α treatment promotes apoptosis and prevents liver regeneration in a transgenic mouse model of chronic hepatitis C.
    Brenndörfer ED; Weiland M; Frelin L; Derk E; Ahlén G; Jiao J; Bode JG; Sällberg M
    Hepatology; 2010 Nov; 52(5):1553-63. PubMed ID: 20886569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.