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4. A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin. Omura T; Kaneko M; Okuma Y; Orba Y; Nagashima K; Takahashi R; Fujitani N; Matsumura S; Hata A; Kubota K; Murahashi K; Uehara T; Nomura Y J Neurochem; 2006 Dec; 99(6):1456-69. PubMed ID: 17059562 [TBL] [Abstract][Full Text] [Related]
5. Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease. Dusonchet J; Bensadoun JC; Schneider BL; Aebischer P Neurobiol Dis; 2009 Jul; 35(1):32-41. PubMed ID: 19348945 [TBL] [Abstract][Full Text] [Related]
6. [Neurodegeneration caused by ER stress?--the pathogenetic mechanisms underlying AR-JP]. Takahashi R Nihon Yakurigaku Zasshi; 2004 Dec; 124(6):375-82. PubMed ID: 15572841 [TBL] [Abstract][Full Text] [Related]
7. MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity. Thomas B; von Coelln R; Mandir AS; Trinkaus DB; Farah MH; Leong Lim K; Calingasan NY; Flint Beal M; Dawson VL; Dawson TM Neurobiol Dis; 2007 May; 26(2):312-22. PubMed ID: 17336077 [TBL] [Abstract][Full Text] [Related]
8. Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Kitao Y; Imai Y; Ozawa K; Kataoka A; Ikeda T; Soda M; Nakimawa K; Kiyama H; Stern DM; Hori O; Wakamatsu K; Ito S; Itohara S; Takahashi R; Ogawa S Hum Mol Genet; 2007 Jan; 16(1):50-60. PubMed ID: 17116640 [TBL] [Abstract][Full Text] [Related]
9. Parkin and endoplasmic reticulum stress. Takahashi R; Imai Y; Hattori N; Mizuno Y Ann N Y Acad Sci; 2003 Jun; 991():101-6. PubMed ID: 12846978 [TBL] [Abstract][Full Text] [Related]
10. Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress. Kubota K; Niinuma Y; Kaneko M; Okuma Y; Sugai M; Omura T; Uesugi M; Uehara T; Hosoi T; Nomura Y J Neurochem; 2006 Jun; 97(5):1259-68. PubMed ID: 16539653 [TBL] [Abstract][Full Text] [Related]
11. [Etiology and pathogenesis of Parkinson's disease: from mitochondrial dysfunctions to familial Parkinson's disease]. Hattori N Rinsho Shinkeigaku; 2004; 44(4-5):241-62. PubMed ID: 15287506 [TBL] [Abstract][Full Text] [Related]
12. CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Imai Y; Soda M; Hatakeyama S; Akagi T; Hashikawa T; Nakayama KI; Takahashi R Mol Cell; 2002 Jul; 10(1):55-67. PubMed ID: 12150907 [TBL] [Abstract][Full Text] [Related]
13. Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults. Hyun DH; Lee M; Halliwell B; Jenner P J Neurosci Res; 2005 Oct; 82(2):232-44. PubMed ID: 16130151 [TBL] [Abstract][Full Text] [Related]
14. Parkin is linked to the ubiquitin pathway. Tanaka K; Suzuki T; Chiba T; Shimura H; Hattori N; Mizuno Y J Mol Med (Berl); 2001 Sep; 79(9):482-94. PubMed ID: 11692161 [TBL] [Abstract][Full Text] [Related]
15. Parkin is protective for substantia nigra dopamine neurons in a tau gene transfer neurodegeneration model. Klein RL; Dayton RD; Henderson KM; Petrucelli L Neurosci Lett; 2006 Jun; 401(1-2):130-5. PubMed ID: 16554120 [TBL] [Abstract][Full Text] [Related]
16. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Imai Y; Soda M; Inoue H; Hattori N; Mizuno Y; Takahashi R Cell; 2001 Jun; 105(7):891-902. PubMed ID: 11439185 [TBL] [Abstract][Full Text] [Related]
17. Autosomal recessive juvenile parkinsonism: a key to understanding nigral degeneration in sporadic Parkinson's disease. Hattori N; Shimura H; Kubo S; Kitada T; Wang M; Asakawa S; Minashima S; Shimizu N; Suzuki T; Tanaka K; Mizuno Y Neuropathology; 2000 Sep; 20 Suppl():S85-90. PubMed ID: 11037196 [TBL] [Abstract][Full Text] [Related]
18. Immunohistochemical localization of a ubiquitin ligase HRD1 in murine brain. Omura T; Kaneko M; Tabei N; Okuma Y; Nomura Y J Neurosci Res; 2008 May; 86(7):1577-87. PubMed ID: 18241051 [TBL] [Abstract][Full Text] [Related]
19. Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Yang Y; Nishimura I; Imai Y; Takahashi R; Lu B Neuron; 2003 Mar; 37(6):911-24. PubMed ID: 12670421 [TBL] [Abstract][Full Text] [Related]
20. Pael-R is accumulated in Lewy bodies of Parkinson's disease. Murakami T; Shoji M; Imai Y; Inoue H; Kawarabayashi T; Matsubara E; Harigaya Y; Sasaki A; Takahashi R; Abe K Ann Neurol; 2004 Mar; 55(3):439-42. PubMed ID: 14991825 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]