BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

461 related articles for article (PubMed ID: 18691555)

  • 1. D77, one benzoic acid derivative, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75.
    Du L; Zhao Y; Chen J; Yang L; Zheng Y; Tang Y; Shen X; Jiang H
    Biochem Biophys Res Commun; 2008 Oct; 375(1):139-44. PubMed ID: 18691555
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitors of the interactions between HIV-1 IN and the cofactor LEDGF/p75.
    De Luca L; Ferro S; Morreale F; De Grazia S; Chimirri A
    ChemMedChem; 2011 Jul; 6(7):1184-91. PubMed ID: 21506277
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 1,4-Bis(5-(naphthalen-1-yl)thiophen-2-yl)naphthalene, a small molecule, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular Lens epithelium-derived growth factor.
    Gu WG; Ip DT; Liu SJ; Chan JH; Wang Y; Zhang X; Zheng YT; Wan DC
    Chem Biol Interact; 2014 Apr; 213():21-7. PubMed ID: 24480521
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus.
    Vandekerckhove L; Christ F; Van Maele B; De Rijck J; Gijsbers R; Van den Haute C; Witvrouw M; Debyser Z
    J Virol; 2006 Feb; 80(4):1886-96. PubMed ID: 16439544
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75.
    Bartholomeeusen K; De Rijck J; Busschots K; Desender L; Gijsbers R; Emiliani S; Benarous R; Debyser Z; Christ F
    J Mol Biol; 2007 Sep; 372(2):407-21. PubMed ID: 17669426
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.
    De Luca L; Barreca ML; Ferro S; Christ F; Iraci N; Gitto R; Monforte AM; Debyser Z; Chimirri A
    ChemMedChem; 2009 Aug; 4(8):1311-6. PubMed ID: 19565598
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insight into the inhibitory mechanism and binding mode between D77 and HIV-1 integrase by molecular modeling methods.
    Li P; Tan JJ; Liu M; Zhang XY; Chen WZ; Wang CX
    J Biomol Struct Dyn; 2011 Oct; 29(2):311-23. PubMed ID: 21875151
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of the LEDGF/p75 binding site in HIV-1 integrase.
    Busschots K; Voet A; De Maeyer M; Rain JC; Emiliani S; Benarous R; Desender L; Debyser Z; Christ F
    J Mol Biol; 2007 Feb; 365(5):1480-92. PubMed ID: 17137594
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: insight into integrase-DNA complex formation and catalysis.
    Al-Mawsawi LQ; Christ F; Dayam R; Debyser Z; Neamati N
    FEBS Lett; 2008 Apr; 582(10):1425-30. PubMed ID: 18331842
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.
    Hombrouck A; De Rijck J; Hendrix J; Vandekerckhove L; Voet A; De Maeyer M; Witvrouw M; Engelborghs Y; Christ F; Gijsbers R; Debyser Z
    PLoS Pathog; 2007 Mar; 3(3):e47. PubMed ID: 17397262
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy.
    Christ F; Debyser Z
    Virology; 2013 Jan; 435(1):102-9. PubMed ID: 23217620
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 1,2,3,4-Tetrahydroisoquinolines as inhibitors of HIV-1 integrase and human LEDGF/p75 interaction.
    George A; Gopi Krishna Reddy A; Satyanarayana G; Raghavendra NK
    Chem Biol Drug Des; 2018 Jun; 91(6):1133-1140. PubMed ID: 29405651
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insights into the interactions between HIV-1 integrase and human LEDGF/p75 by molecular dynamics simulation and free energy calculation.
    Zhao Y; Li W; Zeng J; Liu G; Tang Y
    Proteins; 2008 Aug; 72(2):635-45. PubMed ID: 18247352
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An essential role for LEDGF/p75 in HIV integration.
    Llano M; Saenz DT; Meehan A; Wongthida P; Peretz M; Walker WH; Teo W; Poeschla EM
    Science; 2006 Oct; 314(5798):461-4. PubMed ID: 16959972
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of inhibitors to block interactions of HIV-1 integrase with human LEDGF/p75 via structure-based virtual screening and bioassays.
    Hu G; Li X; Zhang X; Li Y; Ma L; Yang LM; Liu G; Li W; Huang J; Shen X; Hu L; Zheng YT; Tang Y
    J Med Chem; 2012 Nov; 55(22):10108-17. PubMed ID: 23046280
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Screening for antiviral inhibitors of the HIV integrase-LEDGF/p75 interaction using the AlphaScreen luminescent proximity assay.
    Hou Y; McGuinness DE; Prongay AJ; Feld B; Ingravallo P; Ogert RA; Lunn CA; Howe JA
    J Biomol Screen; 2008 Jun; 13(5):406-14. PubMed ID: 18480474
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-based mutagenesis of the integrase-LEDGF/p75 interface uncouples a strict correlation between in vitro protein binding and HIV-1 fitness.
    Rahman S; Lu R; Vandegraaff N; Cherepanov P; Engelman A
    Virology; 2007 Jan; 357(1):79-90. PubMed ID: 16959283
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization and structural analysis of HIV-1 integrase conservation.
    Ceccherini-Silberstein F; Malet I; D'Arrigo R; Antinori A; Marcelin AG; Perno CF
    AIDS Rev; 2009; 11(1):17-29. PubMed ID: 19290031
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-based virtual screening toward the discovery of novel inhibitors for impeding the protein-protein interaction between HIV-1 integrase and human lens epithelium-derived growth factor (LEDGF/p75).
    Panwar U; Singh SK
    J Biomol Struct Dyn; 2018 Sep; 36(12):3199-3217. PubMed ID: 28948865
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication.
    Vandegraaff N; Devroe E; Turlure F; Silver PA; Engelman A
    Virology; 2006 Mar; 346(2):415-26. PubMed ID: 16337983
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.